Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan B. Koenderink"'
Autor:
Jeroen J. M. W. van den Heuvel, Galvin Vredenburg, Frans G. M. Russel, Ab Bilos, Nico P. E. Vermeulen, Jan B. Koenderink
Publikováno v:
Koenderink, J B, van den Heuvel, J J M W, Bilos, A, Vredenburg, G, Vermeulen, N P E & Russel, F G M 2020, ' Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates ', Archives of Toxicology, vol. 94, no. 9, pp. 3027-3032 . https://doi.org/10.1007/s00204-020-02793-4
Archives of Toxicology, 94, 9, pp. 3027-3032
Archives of Toxicology, 94(9), 3027-3032. Springer Verlag
Archives of Toxicology, 94, 3027-3032
Archives of Toxicology
Archives of Toxicology, 94, 9, pp. 3027-3032
Archives of Toxicology, 94(9), 3027-3032. Springer Verlag
Archives of Toxicology, 94, 3027-3032
Archives of Toxicology
Paracetamol (acetaminophen, APAP) overdose is a leading cause of acute drug-induced liver failure. APAP hepatotoxicity is mediated by the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI). NAPQI is inactivated by conjugation with glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a43eb8d3c857f5efff355c65e2a5f3
https://research.vu.nl/en/publications/3a712037-5c16-4ed9-a07a-645cade77b67
https://research.vu.nl/en/publications/3a712037-5c16-4ed9-a07a-645cade77b67
Publikováno v:
Basic & Clinical Pharmacology & Toxicology, 125, 6, pp. 490-498
Basic & Clinical Pharmacology & Toxicology, 125, 490-498
Basic & Clinical Pharmacology & Toxicology, 125, 490-498
Contains fulltext : 215788.pdf (Publisher’s version ) (Closed access) Nicotine is the addiction causing alkaloid in tobacco, and it is used in smoking cessation therapies. Although the metabolic pathways of nicotine are well known and mainly occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e2c59afd9449ffbb36c417688db9b8
https://doi.org/10.1111/bcpt.13281
https://doi.org/10.1111/bcpt.13281
Autor:
Jeroen J. M. W. van den Heuvel, David M. Burger, Roger J. M. Brüggemann, Rob E. Aarnoutse, Vincent J. Lempers, Frans G. M. Russel, Jan B. Koenderink
Publikováno v:
Antimicrobial Agents and Chemotherapy, 60, 3372-9
Antimicrobial Agents and Chemotherapy, 60, 6, pp. 3372-9
Antimicrobial Agents and Chemotherapy, 60, 6, pp. 3372-9
Inhibition of ABC transporters is a common mechanism underlying drug-drug interactions (DDIs). We determined the inhibitory potential of antifungal drugs currently used for invasive fungal infections on ABC transporters P-glycoprotein (P-gp), MRP1 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b4375520f81fc3b81e1c7a48fcf51f
https://doi.org/10.1128/AAC.02931-15
https://doi.org/10.1128/AAC.02931-15
Autor:
Heike Dinter-Heidorn, Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel, Hanneke G. M. Wittgen, Rick Greupink, Petra H.H. van den Broek
Publikováno v:
Molecular Pharmaceutics, 9, 5, pp. 1351-60
Molecular Pharmaceutics, 9, 1351-60
Molecular Pharmaceutics, 9, 1351-60
Contains fulltext : 107834.pdf (Publisher’s version ) (Closed access) Although the CB1 receptor antagonist/inverse agonist rimonabant has positive effects on weight loss and cardiometabolic risk factors, neuropsychiatric side effects have prompted
Autor:
Jurriaan E. M. de Steenwinkel, Gerjo J. de Knegt, Jan B. Koenderink, David M. Burger, Frans G. M. Russel, Lindsey H.M. te Brake, Jeroen J. M. W. van den Heuvel, Rob E. Aarnoutse
Publikováno v:
Tuberculosis, 96, 150-157. Churchill Livingstone
Tuberculosis, 96, 150-7
Tuberculosis, 96, pp. 150-7
Tuberculosis, 96, 150-7
Tuberculosis, 96, pp. 150-7
Contains fulltext : 167529.pdf (Publisher’s version ) (Closed access) BACKGROUND: Multiple-drug therapy for tuberculosis (TB) and TB-associated co-morbidity increase the likelihood of drug-drug interactions (DDIs). Inhibition of membrane transporte
Autor:
Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Sanna R. Rijpma, Robert W. Sauerwein, Maarten van der Velden, Frans G. M. Russel
Publikováno v:
Malaria Journal
Malaria Journal, 13, 359
Malaria Journal, 13, pp. 359
Malaria Journal, 13, 359
Malaria Journal, 13, pp. 359
Contains fulltext : 136792.pdf (Publisher’s version ) (Open Access) BACKGROUND: Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of ads