Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Vibeke, Backer"'
Publikováno v:
Obling, N, Backer, V, Hurst, J R & Bodtger, U 2021, ' Upper airway symptoms associate with the eosinophilic phenotype of copd ', ERJ Open Research, vol. 7, no. 3, 00184-2021 . https://doi.org/10.1183/23120541.00184-2021
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 3 (2021)
Background There is growing evidence that upper airway symptoms coexist with lower airway symptoms in COPD. Still, the prevalence and impact of upper airway disease on the nature and course of COPD remain unclear. We aimed to describe this in a cross
Autor:
Casper Tidemandsen, Anne Vejen Hansen, Zarqa Ali, Elisabeth Juul Gade, Charlotte Suppli Ulrik, Vibeke Backer
Publikováno v:
Journal of Asthma and Allergy. 13:145-152
Background Asthma has been linked with prolonged time to pregnancy compared to healthy controls, also asthma has been linked to a higher need for fertility treatment. However, knowledge of the possible association between allergy and need for fertili
Autor:
Pal B. Szecsi, Kirsten Ohm Kyvik, Camilla Elmose, Vibeke Backer, Simon Francis Thomsen, Jacob P. Thyssen, Steen Stender
Publikováno v:
Thomsen, S F, Elmose, C, Szecsi, P B, Stender, S, Kyvik, K O, Backer, V & Thyssen, J P 2016, ' Filaggrin gene loss-of-function mutations explain discordance of atopic dermatitis within dizygotic twin pairs ', International Journal of Dermatology, vol. 55, no. 12, pp. 1341-1344 . https://doi.org/10.1111/ijd.13401
Objectives This study was designed to examine the association between loss-of-function mutations in the filaggrin gene (FLG) and atopic dermatitis (AD) and asthma in adult twins. Methods A previously well-characterized cohort of 575 adult twins were
Autor:
Vibeke Backer, Johanna Persson, Celeste Porsbjerg, Jonas S. Erjefält, Sangeetha Ramu, Cecilia Andersson, Simon Francis Thomsen, Lena Uller, Asger Sverrild, Sofia Tillgren, Sofia Mogren, Leif Bjermer
Publikováno v:
Allergy and immunology.
Background: Increased mast cell (MC) densities in the airway epithelium is a hallmark of asthma. However, little is known regarding the role and effect of MC mediators on epithelium damaged by respiratory viruses. Aim: To investigate the density of M
Autor:
Vibeke Backer, Celeste Porsbjerg, Pernille Bækgaard Udesen, Asger Sverrild, Anna Von Bülow, Simon Francis Thomsen, Christian Grabow Westergaard
Publikováno v:
Monitoring Airway Disease.
Introduction: Airway inflammation and airway hyperresponsiveness (AHR) in asthma represent two partly different immunological pathways in asthma. The value of adding measures of AHR to airway inflammation in phenotyping asthma is not known. Aim: To e
Autor:
Eric K. Moses, G Zhang, Vibeke Backer, Yong Song, Ingrid A. Laing, Siew-Kim Khoo, Celeste Porsbjerg, Peter LeSouëf, Jing Guo, Michelle J. Schwager
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Song, Y, Schwager, M J, Backer, V, Guo, J, Porsbjerg, C, Khoo, S-K, Laing, I A, Moses, E K, LeSouëf, P & Zhang, G B 2017, ' Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes ', Scientific Reports, vol. 7, 6342 . https://doi.org/10.1038/s41598-017-06791-y
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Song, Y, Schwager, M J, Backer, V, Guo, J, Porsbjerg, C, Khoo, S-K, Laing, I A, Moses, E K, LeSouëf, P & Zhang, G B 2017, ' Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes ', Scientific Reports, vol. 7, 6342 . https://doi.org/10.1038/s41598-017-06791-y
The prevalence of asthma and allergic diseases is disproportionately distributed among different populations, with an increasing trend observed in Western countries. Here we investigated how the environment affected genotype-phenotype association in
Publikováno v:
5.3 Allergy and Immunology.
Background: Although the genetics of overall atopy has been frequently explored, little is known about the influences of genetic factors on development of hypersensitivity to specific allergens. Objective: To study the influence of genetic and enviro
Autor:
Hans Jürgen Hoffmann, Vibeke Backer, Gitte Lund, Ronald Dahl, Inge Kortekaas Krohn, Asger Sverrild, Jonas S. Erjefält
Publikováno v:
Scandinavian Journal of Immunology. 78:352-356
The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with
Publikováno v:
5.2 Monitoring Airway Disease.
Sputum eosinophils (Sp-Eos) and exhaled nitric oxide (FeNO) are usually regarded as two markers of airway inflammation that offer similar information. However, these inflammatory pathways can be activated differently: eosinophils through IL-5 and NO
Publikováno v:
Paediatric and Perinatal Epidemiology. 26:140-145
We examined the risk of atopic diseases in twins born after assisted reproduction. Data on atopic diseases and assisted reproduction in 9694 twin pairs, 3-20 years of age, from the Danish Twin Registry were collected via multidisciplinary questionnai