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pro vyhledávání: '"Peter Vanderslice"'
Autor:
Peter Vanderslice, Darren G. Woodside
Publikováno v:
BioDrugs. 22:85-100
Chronic obstructive pulmonary disease (COPD) and asthma are inflammatory diseases of the lung where a hallmark feature is excessive leukocyte infiltration that leads to tissue injury. Cell adhesion molecules (e.g. selectins and integrins) play a key
Autor:
George W. Holland, Kurt L. Berens, Richard A. F. Dixon, Biediger Ronald J, Peter Vanderslice, Darren G. Woodside
Publikováno v:
Pulmonary pharmacologytherapeutics. 17(1)
Airway inflammation is a hallmark of respiratory diseases such as asthma and chronic obstructive pulmonary disease. Cell adhesion molecules play critical roles in the recruitment and migration of cells to sites of inflammation. Not surprisingly, thes
Autor:
Kathy L. McAbee, Scott Ian L, Timothy P. Kogan, Brian Dupre, Xin Hu, Kassir Jamal M, Peter Vanderslice, Richard A. F. Dixon, Huong Bui, Pamela J. Beck
Publikováno v:
Journal of medicinal chemistry. 41(7)
Reports of a high-affinity ligand for E-selectin, sialyl di-Lewis(x) (sLe(x)Le(x), 1), motivated us to incorporate modifications to previously reported biphenyl-based inhibitors that would provide additional interactions with the protein. These compo