Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amrit Singh"'
Autor:
Nathan Rabinovitch, Meaghan J. Jones, Nicole Gladish, Anna V. Faino, Matthew Strand, Alexander M. Morin, Julie MacIsaac, David T. S. Lin, Paul R. Reynolds, Amrit Singh, Erwin W. Gelfand, Michael S. Kobor, Christopher Carlsten
Publikováno v:
Epigenetics, Vol 16, Iss 2, Pp 177-185 (2021)
Air pollution is associated with early declines in lung function and increased levels of asthma-related cysteinyl leukotrienes (CysLT) but a biological pathway linking this rapid response has not been delineated. In this randomized controlled diesel
Externí odkaz:
https://doaj.org/article/de69246eb7144191a962e43961d0a1b0
Autor:
Daniel He, Chen Xi Yang, Basak Sahin, Amrit Singh, Casey P. Shannon, John-Paul Oliveria, Gail M. Gauvreau, Scott J. Tebbutt
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-10 (2019)
Abstract Background Blood has proven to be a useful resource for molecular analysis in numerous biomedical studies, with peripheral blood mononuclear cells (PBMCs) and whole blood being the major specimen types. However, comparative analyses between
Externí odkaz:
https://doaj.org/article/60d462d4945546638e5e2d7741d0e84a
Autor:
Mohammad A. Alsayegh, Hanan Alshamali, Mousa Khadada, Amanda Ciccolini, Anne K. Ellis, Diana Quint, William Powley, Laurie Lee, Yahya Fiteih, Shairaz Baksh, Harissios Vliagoftis, Sebastien K. Gerega, Brad Millson, Katia Charland, Stephane Barakat, Xichun Sun, Ricardo Jimenez, Susan Waserman, Mark J. FitzGerald, Jacques Hébert, Josiane Cognet-Sicé, Kevin E. Renahan, Saiful Huq, Rishma Chooniedass, Scott Sawyer, Hans Pasterkamp, Allan Becker, Steven G. Smith, Shiyuan Zhang, Kavisha Jayasundara, Claire Tacon, Alex Simidchiev, Gilbert Nadeau, Necdet Gunsoy, Hana Mullerova, Frank Albers, Young Woong Kim, Casey P. Shannon, Amrit Singh, Helen Neighbour, Mark Larché, Scott J. Tebbutt, Annika Klopp, Lorena Vehling, Allan B. Becker, Padmaja Subbarao, Piushkumar J. Mandhane, Stuart E. Turvey, Malcolm R. Sears, Meghan B. Azad, and the Canadian Healthy Infant Longitudinal Development Study Investigators, Keely Loewen, Barret Monchka, Salaheddin M. Mahmud, Geert ‘t Jong, Cristina Longo, Gillian Bartlett, Francine M. Ducharme, Tibor Schuster, Brenda MacGibbon, Tracie Barnett, Michelle L. North, Jeff Brook, Elizabeth Lee, Vanessa Omana, Jenny Thiele, Lisa M. Steacy, Greg Evans, Miriam Diamond, Gordon L. Sussman, Yann Amistani, Kathy Abiteboul, Mark W. Tenn, ChenXi Yang, Christopher Carlsten, Edward M. Conway, Douglas Mack, Yasmin Othman, Colin M. Barber, Chrystyna Kalicinsky, Andrea E. Burke, Mary Messieh, Parameswaran Nair, Chun T. Che, Lindsay Douglas, Joel Liem, Lucy Duan, Charlotte Miller, Pascale Dupuis, Lori A. Connors, Michael N. Fein, Joseph Shuster, Hani Hadi, Brooke Polk, Nikita Raje, Roxane Labrosse, Philippe Bégin, Louis Paradis, Anne Des Roches, Jonathan Lacombe-Barrios, Sanju Mishra, Gina Lacuesta, Meredith Chiasson, Babar Haroon, Kara Robertson, Thomas Issekutz, Desmond Leddin, Stephen Couban, Lori Connors, Adrienne Roos, Amin Kanani, Edmond S. Chan, Robert Schellenberg, Lana Rosenfield, Anna Cvetkovic, Kevin Woodward, Jaclyn Quirt, Wade T. A. Watson, Edson Castilho, Jennifer A. Sullivan, Beverley Temple, Donna Martin, Victoria E. Cook, Christopher Mills, Elodie Portales-Casamar, Lisa W. Fu, Alexander Ho, Jeffrey Zaltzman, Lucy Chen, Peter Vadas, Sofianne Gabrielli, Ann Clarke, Harley Eisman, Judy Morris, Lawrence Joseph, Sebastien LaVieille, Moshe Ben-Shoshan, François Graham, Charles Barnes, Jay Portnoy, Vincent Stagg, Elinor Simons, Diana Lefebvre, David Dai, Piushkumar Mandhane, Malcolm Sears, Herman Tam, F. Estelle R. Simons, Dhaifallah Alotaibi, Bassel Dawod, Matthew C. Tunis, Jean Marshall, Marylin Desjardins, Marianne Béland, Duncan Lejtenyi, Jean-Phillipe Drolet, Martine Lemire, Christos Tsoukas, Francisco J.D. Noya, Reza Alizadehfar, Christine T. McCusker, Bruce D. Mazer, Danay Maestre-Batlle, Evelyn Gunawan, Christopher F. Rider, Anette K. Bølling, Olga M. Pena, Daniel Suez, Isaac Melamed, Iftikhar Hussain, Mark Stein, Sudhir Gupta, Kenneth Paris, Sandor Fritsch, Christelle Bourgeois, Heinz Leibl, Barbara McCoy, Martin Noel, Leman Yel, Ori Scott, Brenda Reid, Adelle Atkinson, Vy Hong-Diep Kim, Chaim M. Roifman, Eyal Grunebaum, Eiman AlSelahi, Fernando Aleman, Amber Oberle, Mike Trus, Gordon Sussman, Amin S. Kanani, Olivier Chambenoi, Sima Chiva-Razavi, Savannah Grodecki, Nikhil Joshi, Peter Menikefs, David Holt, Teresa Pun, Damian Tworek, Raphael Hanna, Delia Heroux, Elli Rosenberg, Leah Stiemsma, Stuart Turvey, Judah Denburg, Christopher Mill, Timothy Teoh, Preeti Zimmer, Vishal Avinashi, Mihaela Paina, Ahmed A. Darwish Hassan, John Paul Oliveria, Chris Olesovsky, Gail Gauvreau, Linda Pedder, Paul K. Keith, Greg Plunkett, Michelle Bolner, Persia Pourshahnazari, Donald Stark, Kateryna Vostretsova, Andrew Moses, Andrew Wakeman, Alexander Singer, Thomas Gerstner, Elissa Abrams, Sara F. Johnson, Roberta L. Woodgate
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 13, Iss S1, Pp 1-19 (2017)
Externí odkaz:
https://doaj.org/article/e2baf16d1cbe42078ca099b53c80d5dd
Autor:
Vivek D. Gandhi, Jacqueline-Yvonne Cephus, Allison E. Norlander, Nowrin U. Chowdhury, Jian Zhang, Zachary J. Ceneviva, Elie Tannous, Vasiliy V. Polosukhin, Nathan D. Putz, Nancy Wickersham, Amrit Singh, Lorraine B. Ware, Julie A. Bastarache, Ciara M. Shaver, Hong Wei Chu, R. Stokes Peebles, Dawn C. Newcomb
Publikováno v:
Journal of Clinical Investigation. 132
Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and IL-13 production and eosinophil infiltration. Foxp3+ Tregs suppress an
Autor:
Scott J. Tebbutt, Casey P. Shannon, Basak Sahin, Daniel He, John-Paul Oliveria, Gail M. Gauvreau, Amrit Singh, Chen Xi Yang
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-10 (2019)
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Background Blood has proven to be a useful resource for molecular analysis in numerous biomedical studies, with peripheral blood mononuclear cells (PBMCs) and whole blood being the major specimen types. However, comparative analyses between these two
Autor:
Nicole Gladish, Amrit Singh, Alexander M. Morin, David T.S. Lin, Erwin W Gelfand, Christopher Carlsten, Anna Faino, Paul R. Reynolds, J.L. MacIsaac, Matthew Strand, Meaghan J. Jones, Nathan Rabinovitch, Michael S. Kobor
Publikováno v:
Epigenetics
Air pollution is associated with early declines in lung function and increased levels of asthma-related cysteinyl leukotrienes (CysLT) but a biological pathway linking this rapid response has not been delineated. In this randomized controlled diesel
Autor:
Christopher Carlsten, Anna Faino, Nathan Rabinovitch, Amrit Singh, Michael S. Kobor, Paul R. Reynolds, Meaghan J. Jones, Julia L. MacIsaac, Alexander M. Morin, Matthew Strand, Erwin W. Gelfand
Rationale: Acute exposure to ambient particle matter is associated with increased levels of the cysteinyl leukotriene (CysLT) biomarker, urinary leukotriene E4 (uLTE(4)), in subjects with asthma. Objectives: The role of CysLTs in mediating asthma wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8467942716fba17724f0e0ff9c635c4
https://europepmc.org/articles/PMC5955031/
https://europepmc.org/articles/PMC5955031/
Autor:
Chen Xi Yang, Robert Balshaw, Young Woong Kim, Scott J. Tebbutt, Casey P. Shannon, J. Mark FitzGerald, Amrit Singh, Gabriela V. Cohen Freue, Paul M. O'Byrne, Gail M. Gauvreau, Louis-Philippe Boulet
Publikováno v:
Singh, A, Shannon, C P, Kim, Y W, Yang, C X, Balshaw, R, Cohen Freue, G V, Gauvreau, G M, FitzGerald, J M, Boulet, L-P, O'Byrne, P M & Tebbutt, S J 2018, ' Novel Blood-based Transcriptional Biomarker Panels Predict the Late-Phase Asthmatic Response ', American Journal of Respiratory and Critical Care Medicine, vol. 197, no. 4, pp. 450-462 . https://doi.org/10.1164/rccm.201701-0110OC
RATIONALE: The allergen inhalation challenge is used in clinical trials to test the efficacy of new treatments in attenuating the late-phase asthmatic response (LAR) and associated airway inflammation in subjects with allergic asthma. However, not al
Autor:
Young Woong Kim, Amrit Singh, Chen Xi Yang, Edward M. Conway, Christopher Carlsten, Scott J. Tebbutt
Publikováno v:
American journal of respiratory and critical care medicine. 196(12)
Western red cedar asthma is the most common form of occupational asthma in the Pacific Northwest region of North America and is caused by a low molecular weight molecule, plicatic acid, found in western red cedar wood. In the present study, periphera
Autor:
Duncan Lejtenyi, Vincent Stagg, Michael N. Fein, Young Woong Kim, Mark W. Tenn, Peter Vadas, Marylin Desjardins, David Dai, Allan B. Becker, Charlotte Miller, David Holt, Elissa M. Abrams, Jaclyn Quirt, Brenda Reid, Leman Yel, Roxane Labrosse, Daniel Suez, Dhaifallah Alotaibi, Helen Neighbour, Alex Simidchiev, Eiman Al-Selahi, Thomas V. Gerstner, Mary Messieh, Sanju Mishra, Edward M. Conway, Lucy Duan, Xichun Sun, Amin S. Kanani, Chaim M. Roifman, Mark Stein, Delia Heroux, ChenXi Yang, Chrystyna Kalicinsky, Chun T. Che, Barbara McCoy, Louis Paradis, Herman Tam, Martine Lemire, Donna Martin, Philippe Bégin, Linda Pedder, Jeffrey S. Zaltzman, Timothy Teoh, Greg J. Evans, Preeti Zimmer, Lucy Chen, Christopher Mill, Kateryna Vostretsova, Scott J. Tebbutt, Casey P. Shannon, Gillian Bartlett, Nikita Raje, Evelyn Gunawan, Bruce Mazer, Kevin E. Renahan, Stephane Barakat, Charles S. Barnes, Sudhir Gupta, Salaheddin M. Mahmud, Elli Rosenberg, Alexander Ho, Michael Trus, Meghan B. Azad, Harley Eisman, Ricardo Jimenez, Savannah Grodecki, Jean-Phillipe Drolet, Christelle Bourgeois, Lisa W. Fu, Gail M. Gauvreau, Cristina Longo, Shiyuan Zhang, Andrea E. Burke, Frank Albers, Heinz Leibl, Victoria E. Cook, Christopher Carlsten, Elinor Simons, Jenny Thiele, Amber Oberle, Padmaja Subbarao, Matthew C. Tunis, Ahmed A. Darwish Hassan, R. Robert Schellenberg, Alexander Singer, Jennifer A. Sullivan, Paul K. Keith, Isaac Melamed, Meredith D. Chiasson, Andrew Moses, Amin Kanani, Bassel Dawod, Danay Maestre-Batlle, Diana L. Lefebvre, Rishma Chooniedass, Jeffrey R. Brook, Gina Lacuesta, Adelle Atkinson, Lorena Vehling, Sofianne Gabrielli, Tracie A. Barnett, Judy Morris, Iftikhar Hussain, Tibor Schuster, Edson Castilho, Edmond S. Chan, Colin Barber, Mihaela Paina, Brooke I. Polk, Amrit Singh, Keely Loewen, Brenda MacGibbon, Lisa M. Steacy, Michelle L. North, Yasmin Othman, Gordon L. Sussman, Elodie Portales-Casamar, Yahya Fiteih, Joel Liem, Diana Quint, Sandor Fritsch, Yann Amistani, Hanan Alshamali, Kenneth Paris, Francisco J.D. Noya, Vanessa Omana, Jacques Hébert, Harissios Vliagoftis, Vishal Avinashi, Moshe Ben-Shoshan, Olga M. Pena, Lori A. Connors, Annika Klopp, Andrew Wakeman, Desmond Leddin, François Graham, Ori Scott, Lori Connors, Amanda Ciccolini, Hans Pasterkamp, Eyal Grunebaum, Stephen Couban, Sebastien LaVieille, Geert W. ‘t Jong, Claire Tacon, Kavisha Jayasundara, Anne K. Ellis, S.E. Turvey, Beverley Temple, Fernando Aleman, Jean S. Marshall, Malcolm R. Sears, Peter Menikefs, Kevin Woodward, Roberta L. Woodgate, Piushkumar J. Mandhane, Martin Noel, Marianne Beland, Necdet B Gunsoy, John-Paul Oliveria, Saiful Huq, Adrienne Roos, Josiane Cognet-Sicé, Lawrence Joseph, Mark Larché, Anne Des Roches, Katia Charland, Michelle Bolner, Anette Kocbach Bølling, Gordon Sussman, Teresa Pun, Olivier Chambenoi, Nikhil Joshi, Mark FitzGerald, Francine M. Ducharme, M.R. Sears, Vy Hong-Diep Kim, Raphael Hanna, Leah T. Stiemsma, Piushkumar Mandhane, Brad Millson, Donald Stark, Persia Pourshahnazari, Laurie Lee, Mohammad A. Alsayegh, Joseph Shuster, Hani Hadi, Thomas B. Issekutz, Anna Cvetkovic, Barret A. Monchka, Christos M. Tsoukas, Jonathan Lacombe-Barrios, Douglas P. Mack, Elizabeth A. Lee, Susan Waserman, Sebastien K. Gerega, Scott Sawyer, Parameswaran Nair, Shairaz Baksh, Miriam Diamond, Judah A. Denburg, Wade Watson, Ann E. Clarke, Christopher F. Rider, Christopher Mills, Kara Robertson, Jay M. Portnoy, Sima Chiva-Razavi, Lindsay Douglas, Kathy Abiteboul, Damian Tworek, Babar Haroon, F. Estelle R. Simons, Hana Müllerová, Pascale Dupuis, Sara F. Johnson, Gilbert Nadeau, William Powley, Lana Rosenfield, Stuart E. Turvey, Reza Alizadehfar, Greg Plunkett, Steven G. Smith, Chris Olesovsky, Christine McCusker, Mousa Khadada
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 13, Iss S1, Pp 1-19 (2017)
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology