Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yohei Katoh"'
Publikováno v:
Molecular Biology of the Cell
Cilia sense and transduce extracellular signals via specific receptors. The intraflagellar transport (IFT) machinery mediates not only bidirectional protein trafficking within cilia but also the import/export of ciliary proteins across the ciliary ga
Autor:
Shuhei Chiba, Luxiaoxue Liang, Ryota Takei, Kazuhisa Nakayama, Yohei Katoh, Takuya Kobayashi, Misato Okazaki
Publikováno v:
Molecular Biology of the Cell
Cilia are plasma membrane protrusions that act as cellular antennae and propellers in eukaryotes. To achieve their sensory and motile functions, cilia maintain protein and lipid compositions that are distinct from those of the cell body. The transiti
Publikováno v:
Molecular Biology of the Cell
RABL2 interacts with the intraflagellar transport-B (IFT-B) complex and CEP19 in a mutually exclusive manner. A point mutation of RABL2 found in sperm motility–defective mice abolishes its binding to IFT-B but not to CEP19. A RABL2-defective Chlamy
Publikováno v:
Molecular Biology of the Cell
The ciliary kinesin KIF17 is a cargo, but not a motor, of the IFT-B complex. The ciliary entry of KIF17 through the transition zone depends on its binding to IFT-B, as well as on its nuclear localization signal.
Cilia function as cellular antenn
Cilia function as cellular antenn
Publikováno v:
Molecular Biology of the Cell
The IFT-A complex is divided into core and peripheral subcomplexes composed of IFT122/IFT140/IFT144 and IFT43/IFT121/IFT139, respectively. IFT139-KO and IFT144-KO cell analyses show that IFT139 is dispensable for IFT-A assembly but essential for retr
Autor:
Yoshiki Tanaka, Kazuhisa Nakayama, Hye-Won Shin, Gaku Tanaka, Yohei Katoh, Takahiro Shima, Hiroyuki Takatsu, Natsuki Ono
Publikováno v:
Molecular Biology of the Cell
ATP9A is localized to phosphatidylserine-positive early and recycling endosomes, but not late endosomes, in HeLa cells. ATP9A plays a crucial role in recycling of transferrin and glucose transporter 1 from endosomes to the plasma membrane.
Type
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Publikováno v:
Molecular Biology of the Cell
The dynein-2 complex drives retrograde ciliary protein trafficking by associating with the intraflagellar transport (IFT) machinery, containing IFT-A and IFT-B complexes. We recently showed that the dynein-2 complex, which comprises 11 subunits, can
Autor:
Hye-Won Shin, Hideaki Yamamoto, Hiroshi Koga, Kazuhisa Nakayama, Yohei Katoh, Senye Takahashi
Publikováno v:
Molecular Biology of the Cell
Rab14 binds in a GTP-dependent manner to RUFY1/Rabip4, which had been originally identified as a Rab4 effector. We suggest that Rab14 and Rab4 act sequentially; Rab14 is required for recruitment of RUFY1 onto endosomes and subsequent RUFY1 interactio