Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yong J. Lee"'
Autor:
Kalishwaralal Kalimuthu, Chenicheri K. Keerthana, Manikandan Mohan, Jaison Arivalagan, Johnson Retnaraj Samuel Selvan Christyraj, Michael A. Firer, Mohammad Haroon Asif Choudry, Ruby John Anto, Yong J. Lee
Publikováno v:
J Cell Biochem
Selenium is incorporated into the body via the selenocysteine biosynthesis pathway, which is critical in the synthesis of selenoproteins such as glutathione peroxidases and thioredoxin reductases. Selenoproteins, which play a key role in several biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf9fd8fbcf1fd7c7a0d17649480dfd3
https://europepmc.org/articles/PMC8940641/
https://europepmc.org/articles/PMC8940641/
Autor:
Xu Luo, Yong Seok Park, Kalishwaralal Kalimuthu, M. Haroon A. Choudry, David L. Bartlett, Young Sun Lee, Yong J. Lee
Publikováno v:
Apoptosis
Ferroptosis is considered a distinctive form of cell death compared to other types of death such as apoptosis. It is known to result from iron-dependent accumulation of lipid peroxides rather than caspase activation. However, we reported recently tha
Autor:
Lesley M. Foley, Hima Makala, Haroon A. Choudry, Robin Frederick, Ashok K. Dilly, Jianxia Guo, David L. Bartlett, Jan H. Beumer, T. Kevin Hitchens, Yong J. Lee, Brendon D. Honick, Anuleka Elapavaluru, Lora H. Rigatti, Sachin Velankar
Publikováno v:
Transl Res
Abundant intraperitoneal (IP) accumulation of extracellular mucus in patients with appendiceal mucinous carcinoma peritonei (MCP) causes compressive organ dysfunction and prevents delivery of chemotherapeutic drugs to cancer cells. We hypothesized th
Autor:
Xinxin Song, Haroon A. Choudry, Yong J. Lee, Yong Tae Kwon, Young Sun Lee, David L. Bartlett, Ashok K. Dilly, Dae Hee Lee
Publikováno v:
Molecular Cancer Research. 16:1077-1091
Emerging evidence demonstrates that autophagy and apoptosis are interconnected and their interplay greatly affects cell death. However, the key regulators in this crosstalk remain elusive. Therefore, the role of N-terminal arginylated BiP (R-BiP)/Bec
Autor:
Hima Makala, Kalishwaralal Kalimuthu, Young Sun Lee, Yong Seok Park, Yong J. Lee, Simon C. Watkins, Yong Tae Kwon, M. Haroon A. Choudry, David L. Bartlett
Publikováno v:
J Cell Physiol
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Autor:
Lisa Bailey, David L. Bartlett, Xinxin Song, Se Hoon Hong, William T. Kwon, Yong J. Lee, Yong Tae Kwon, Per H. Basse
Publikováno v:
Molecular Cancer Therapeutics. 15:1591-1601
Since its discovery in 1995, TNF-related apoptosis-inducing ligand (TRAIL) has sparked growing interest among oncologists due to its remarkable ability to induce apoptosis in malignant human cells, but not in most normal cells. However, one major dra
Autor:
Ashok K. Dilly, Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Haroon A. Choudry, Xinxin Song
Publikováno v:
Molecular Cancer Research. 13:1533-1543
Colorectal peritoneal carcinomatosis (CPC) exhibits severe tumor hypoxia, leading to drug resistance and disease aggressiveness. This study demonstrates that the combination of the chemotherapeutic agent mitomycin C with the proteasome inhibitor bort
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Autor:
Dae Hee Lee, Jian Yu, David L. Bartlett, Yong Seok Park, Haroon A. Choudry, Yong J. Lee, Seong Hye Park, So Yeon Jeong, Young Sun Lee, Sang Cheul Oh
Publikováno v:
Journal of cellular biochemistry. 120(1)
Ferroptosis is considered genetically and biochemically distinct from other forms of cell death. In this study, we examined whether ferroptosis shares cell death pathways with other types of cell death. When human colon cancer HCT116, CX-1, and LS174
Publikováno v:
Molecular cancer research : MCR. 16(7)
Since its discovery in 2012, ferroptosis has been well characterized by the accumulation of lipid peroxides due to the failure of glutathione-dependent antioxidant defenses. It is known as an iron-dependent form of programmed cell death, which is dis
Publikováno v:
Molecular Cancer Research. 10:1567-1579
Colorectal cancer is the third leading cause of cancer-related mortality in the world. The main cause of death because of colorectal cancer is hepatic metastases, which can be treated using isolated hepatic perfusion (IHP), allowing treatment of colo