Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Yasmine, Belkaid"'
Autor:
Jia Nie, Andrea C. Carpenter, Laura B. Chopp, Ting Chen, Mariah Balmaceno-Criss, Thomas Ciucci, Qi Xiao, Michael C. Kelly, Dorian B. McGavern, Yasmine Belkaid, Rémy Bosselut
Publikováno v:
Nat Immunol
TCRαβ+ CD8α+ CD8β− intraepithelial lymphocytes (CD8αα IEL) differentiate from thymic IEL precursors (IELp) and contribute to gut homeostasis. However, their development remains poorly understood. Here we show that the zinc finger transcriptio
Autor:
Ivan Vujkovic-Cvijin, Hugh C. Welles, Connie W. Y. Ha, Lutfi Huq, Shreni Mistry, Jason M. Brenchley, Giorgio Trinchieri, Suzanne Devkota, Yasmine Belkaid
Publikováno v:
Science translational medicine, vol 14, iss 658
Sci Transl Med
Sci Transl Med
Unique gut microbiota compositions have been associated with inflammatory diseases, but identifying gut bacterial functions linked to immune activation in humans remains challenging. Translocation of pathogens from mucosal surfaces into peripheral ti
Autor:
Yasmine Belkaid, Michail S. Lionakis, Mukil Natarajan, Olle Kämpe, Åsa Hallgren, Ehsan Chitsaz, David E. Kleiner, Theo Heller, Rabab Ali, Elise M. N. Ferré, Sungyoung Auh, Yannis Hadjiyannis, David M. Chascsa, Jamie Marko, Thomas L. Simcox, Christopher Koh, Stacey R. Rose, Hawwa Alao, Mariam Quinones
Publikováno v:
Hepatology
Background and aims Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), caused by autoimmune regulator (AIRE) mutations, manifests with chronic mucocutaneous candidiasis (CMC) and multisystem autoimmunity, most often hypoparathyr
Autor:
Loki Natarajan, Jack Sklar, Rob Knight, Lingjing Jiang, Ivan Vujkovic-Cvijin, Yasmine Belkaid
Publikováno v:
Nature
Nature, vol 587, iss 7834
Nature, vol 587, iss 7834
Low concordance between studies that examine the role of microbiota in human diseases is a pervasive challenge that limits the capacity to identify causal relationships between host-associated microorganisms and pathology. The risk of obtaining false
Publikováno v:
Science
Atypical T cells take a different path Conventional T cells recognize peptides that are presented by polymorphic major histocompatibility complexes (MHCs). By contrast, many tissue-resident T cells, such as mucosal-associated invariant T cells, invar
Autor:
Yasmine Belkaid, Brian Sellers, Irini Sereti, Ornella Sortino, Neeltje A. Kootstra, Peter Reiss, J. Sklar, Ivan Vujkovic-Cvijin, Ferdinand W Wit, Eveline Verheij, J. Ananworanich, M. Schim van der Loeff, Jason M. Brenchley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, 11(1):2448. Nature Publishing Group
Nature Communications
Nature communications, 11(1):2448. Nature Publishing Group
Loss of gut mucosal integrity and an aberrant gut microbiota are proposed mechanisms contributing to chronic inflammation and increased morbidity and mortality during antiretroviral-treated HIV disease. Sexual practice has recently been uncovered as
Autor:
Heather D. Hickman, Chyi-Chia Richard Lee, Peter Olbrich, Jean K. Lim, Daniel Chauss, Vasileios Oikonomou, Daniel L. Barber, Philip M. Murphy, Monica M. Schmitt, Tilo Freiwald, Marc Swidergall, Stefania Pittaluga, Steven M. Holland, Daniel Martin, Luigi D. Notarangelo, Oliver J. Harrison, Scott G. Filler, Lindsey B. Rosen, Ian A. Myles, Wint Lwin, Sergio M. Pontejo, Behdad Afzali, Timothy J. Break, Niki M. Moutsopoulos, Vincent M. Bruno, Julie Alejo, Jigar V. Desai, Nicolas Bouladoux, Elise M. N. Ferré, Norma V. Solis, Mitsuru Matsumoto, David V. Serreze, Yasmine Belkaid, Andy Renteria, John P. Shannon, Nicolas Dutzan, Teresa Greenwell-Wild, Michail S. Lionakis, Drake W. Williams, Kevin W. Hoffman, Muthulekha Swamydas, Mark S. Anderson
Publikováno v:
Science
Puel and Casanova and Kisand et al . challenge our conclusions that interferonopathy and not IL-17/IL-22 autoantibodies promote candidiasis in autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy. We acknowledge that conclusive evidence
Autor:
Verena M. Link, Rose-Marie Karlsson, Jigar V. Desai, Han-Yu Shih, Ai Ing Lim, Oliver J. Harrison, Michail S. Lionakis, Heather A. Cameron, Seong-Ji Han, Taryn McFadden, Taylor K. Farley, Apollo Stacy, Djalma S. Lima-Junior, Yasmine Belkaid
Publikováno v:
Science
Mom’s IL-6 rewires baby’s gut immunity Most infections that occur during pregnancy are mild and transient. However, whether such pathogen encounters can shape the long-term trajectory of the offspring’s immune system remains unclear. Lim et al
Autor:
Julie Alejo, Jigar V. Desai, Ian A. Myles, Niki M. Moutsopoulos, Peter Olbrich, Michail S. Lionakis, Vasileios Oikonomou, Philip M. Murphy, Norma V. Solis, Tilo Freiwald, Scott G. Filler, Heather D. Hickman, Steven M. Holland, Stefania Pittaluga, Sergio M. Pontejo, Teresa Greenwell-Wild, Marc Swidergall, Lindsey B. Rosen, Kevin W. Hoffman, Mark S. Anderson, Timothy J. Break, Vincent M. Bruno, Daniel Chauss, Wint Lwin, Muthulekha Swamydas, Behdad Afzali, Chyi-Chia Richard Lee, David V. Serreze, Daniel Martin, Oliver J. Harrison, Yasmine Belkaid, Jean K. Lim, Andy Renteria, John P. Shannon, Nicolas Dutzan, Monica M. Schmitt, Daniel L. Barber, Luigi D. Notarangelo, Drake W. Williams, Elise M. N. Ferré, Mitsuru Matsumoto, Nicolas Bouladoux
Publikováno v:
Science
Science (New York, N.Y.), vol 371, iss 6526
Science (New York, N.Y.), vol 371, iss 6526
INTRODUCTION: Studies of monogenic diseases have uncovered the importance of immune pathways in human tissue-specific immunity and antimicrobial defense. In particular, human inborn errors of the interleukin-17 (IL-17) receptor signaling pathway and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9858aefc910c2c232d75d169c1c48067
https://hdl.handle.net/11391/1537575
https://hdl.handle.net/11391/1537575
Autor:
Brydie R. Huckestein, Oliver J. Harrison, Deyi Yang, Ansen H.P. Burr, Justin T. Tometich, Jason A. Hall, Sean P. Spencer, Elizabeth B. Norton, Jonathan L. Linehan, Yasmine Belkaid, Amrita Bhattacharjee, Denise Morais da Fonseca, Abigail E. Overacre-Delgoffe, Timothy W. Hand
Publikováno v:
Immunity
Summary Environmental enteric dysfunction (EED) is a gastrointestinal inflammatory disease caused by malnutrition and chronic infection. EED is associated with stunting in children and reduced efficacy of oral vaccines. To study the mechanisms of ora