Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Peter K, Gregersen"'
Autor:
Kazuyoshi, Ishigaki, Saori, Sakaue, Chikashi, Terao, Yang, Luo, Kyuto, Sonehara, Kensuke, Yamaguchi, Tiffany, Amariuta, Chun Lai, Too, Vincent A, Laufer, Ian C, Scott, Sebastien, Viatte, Meiko, Takahashi, Koichiro, Ohmura, Akira, Murasawa, Motomu, Hashimoto, Hiromu, Ito, Mohammed, Hammoudeh, Samar Al, Emadi, Basel K, Masri, Hussein, Halabi, Humeira, Badsha, Imad W, Uthman, Xin, Wu, Li, Lin, Ting, Li, Darren, Plant, Anne, Barton, Gisela, Orozco, Suzanne M M, Verstappen, John, Bowes, Alexander J, MacGregor, Suguru, Honda, Masaru, Koido, Kohei, Tomizuka, Yoichiro, Kamatani, Hiroaki, Tanaka, Eiichi, Tanaka, Akari, Suzuki, Yuichi, Maeda, Kenichi, Yamamoto, Satoru, Miyawaki, Gang, Xie, Jinyi, Zhang, Christopher I, Amos, Edward, Keystone, Gertjan, Wolbink, Irene, van der Horst-Bruinsma, Jing, Cui, Katherine P, Liao, Robert J, Carroll, Hye-Soon, Lee, So-Young, Bang, Katherine A, Siminovitch, Niek, de Vries, Lars, Alfredsson, Solbritt, Rantapää-Dahlqvist, Elizabeth W, Karlson, Sang-Cheol, Bae, Robert P, Kimberly, Jeffrey C, Edberg, Xavier, Mariette, Tom, Huizinga, Philippe, Dieudé, Matthias, Schneider, Martin, Kerick, Joshua C, Denny, Koichi, Matsuda, Keitaro, Matsuo, Tsuneyo, Mimori, Fumihiko, Matsuda, Keishi, Fujio, Yoshiya, Tanaka, Atsushi, Kumanogoh, Matthew, Traylor, Cathryn M, Lewis, Stephen, Eyre, Huji, Xu, Richa, Saxena, Thurayya, Arayssi, Yuta, Kochi, Katsunori, Ikari, Masayoshi, Harigai, Peter K, Gregersen, Kazuhiko, Yamamoto, S, Louis Bridges, Leonid, Padyukov, Javier, Martin, Lars, Klareskog, Yukinori, Okada, Soumya, Raychaudhuri
Publikováno v:
Nature Genetics, 54, 1640-1651
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet
Multi-ancestry genome-wide association analyses identify 124 risk loci for rheumatoid arthritis, of which 34 are novel. A polygenic risk score based on multi-ancestry data showed comparable performance between populations of European and East Asian a
Autor:
Christine N. Metz, Xiangying Xue, Prodyot K Chatterjee, Robert Adelson, Michael Brines, Kevin J. Tracey, Peter K. Gregersen, Valentin A. Pavlov
Publikováno v:
bioRxiv
BackgroundOver 65% of American women are overweight or obese. Obesity and the closely related metabolic syndrome increase the probability for developing several diseases, including cardiovascular disease (CVD). Chronic low-grade inflammation has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af28501c4aacf9ca0a197a61ca2485e8
https://doi.org/10.1101/2023.05.18.540879
https://doi.org/10.1101/2023.05.18.540879
Autor:
Daniela, Matuozzo, Estelle, Talouarn, Astrid, Marchal, Jeremy, Manry, Yoann, Seeleuthner, Yu, Zhang, Alexandre, Bolze, Matthieu, Chaldebas, Baptiste, Milisavljevic, Peng, Zhang, Adrian, Gervais, Paul, Bastard, Takaki, Asano, Lucy, Bizien, Federica, Barzaghi, Hassan, Abolhassani, Ahmad Abou, Tayoun, Alessandro, Aiuti, Ilad Alavi, Darazam, Luis M, Allende, Rebeca, Alonso-Arias, Andrés Augusto, Arias, Gokhan, Aytekin, Peter, Bergman, Simone, Bondesan, Yenan T, Bryceson, Ingrid G, Bustos, Oscar, Cabrera-Marante, Sheila, Carcel, Paola, Carrera, Giorgio, Casari, Khalil, Chaïbi, Roger, Colobran, Antonio, Condino-Neto, Laura E, Covill, Loubna, El Zein, Carlos, Flores, Peter K, Gregersen, Marta, Gut, Filomeen, Haerynck, Rabih, Halwani, Selda, Hancerli, Lennart, Hammarström, Nevin, Hatipoğlu, Adem, Karbuz, Sevgi, Keles, Christèle, Kyheng, Rafael, Leon-Lopez, Jose Luis, Franco, Davood, Mansouri, Javier, Martinez-Picado, Ozge Metin, Akcan, Isabelle, Migeotte, Pierre-Emmanuel, Morange, Guillaume, Morelle, Andrea, Martin-Nalda, Giuseppe, Novelli, Antonio, Novelli, Tayfun, Ozcelik, Figen, Palabiyik, Qiang, Pan-Hammarström, Rebeca, Pérez de Diego, Laura, Planas-Serra, Daniel E, Pleguezuelo, Carolina, Prando, Aurora, Pujol, Luis Felipe, Reyes, Jacques G, Rivière, Carlos, Rodriguez-Gallego, Julian, Rojas, Patrizia, Rovere-Querini, Agatha, Schlüter, Mohammad, Shahrooei, Ali, Sobh, Pere, Soler-Palacin, Yacine, Tandjaoui-Lambiotte, Imran, Tipu, Cristina, Tresoldi, Jesus, Troya, Diederik, van de Beek, Mayana, Zatz, Pawel, Zawadzki, Saleh Zaid, Al-Muhsen, Hagit, Baris-Feldman, Manish J, Butte, Stefan N, Constantinescu, Megan A, Cooper, Clifton L, Dalgard, Jacques, Fellay, James R, Heath, Yu-Lung, Lau, Richard P, Lifton, Tom, Maniatis, Trine H, Mogensen, Horst, von Bernuth, Alban, Lermine, Michel, Vidaud, Anne, Boland, Jean-François, Deleuze, Robert, Nussbaum, Amanda, Kahn-Kirby, France, Mentre, Sarah, Tubiana, Guy, Gorochov, Florence, Tubach, Pierre, Hausfater, Isabelle, Meyts, Shen-Ying, Zhang, Anne, Puel, Luigi D, Notarangelo, Stephanie, Boisson-Dupuis, Helen C, Su, Bertrand, Boisson, Emmanuelle, Jouanguy, Jean-Laurent, Casanova, Qian, Zhang, Laurent, Abel, Aurélie, Cobat
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
medRxiv
Universidade de São Paulo (USP)
instacron:USP
medRxiv
BackgroundWe previously reported inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity in 1-5% of unvaccinated patients with life-threatening COVID-19, and auto-antibodies against type I IFN in another 15-20% of cases.MethodsWe r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2b2b888dfa2d32ea41a056674b1215
https://doi.org/10.1101/2022.10.22.22281221
https://doi.org/10.1101/2022.10.22.22281221
Autor:
Jill M. Norris, Marie L. Feser, Kevin D. Deane, V. Michael Holers, Fan Yang, Michael H. Weisman, M. Kristen Demoruelle, Peter K. Gregersen, Tessa L. Crume, Ted R. Mikuls, Jane H. Buckner, Elizabeth A. Bemis, Jennifer Seifert, Kristen J. Polinski, Richard M. Keating, Michael J. Clare-Salzler, James R. O'Dell, Nichole Reisdorph
Publikováno v:
Arthritis Rheumatol
OBJECTIVE To determine the association of polyunsaturated fatty acid (PUFA)-derived lipid mediators with progression from rheumatoid arthritis (RA)-related autoimmunity to inflammatory arthritis (IA). METHODS We conducted a prospective cohort study u
Autor:
James R. O'Dell, Christopher C. Striebich, Stacey Brake, Perry M. Nicassio, Kevin D. Deane, V. Michael Holers, Jill M. Norris, Jennifer Seifert, Peter K. Gregersen, Jane H. Buckner, Elizabeth A. Bemis, Michael H. Weisman, Richard M. Keating, M. Kristen Demoruelle, Marie L. Feser, Ted R. Mikuls, Kristen J. Polinski
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE The aim of this study was to determine the association of perceived stress with incident inflammatory arthritis (IA) defined as having at least 1 joint consistent with rheumatoid arthritis (RA)-like synovitis based on examination. METHODS W
Autor:
Maria Gutierrez-Arcelus, A. Helena Jonsson, Jatin Arora, Cristina Navarrete, Stephen S. Rich, Michael B. Brenner, Susan K. Hannes, Deepak A. Rao, Tõnu Esko, Jerome I. Rotter, Tiffany Amariuta, Yuriy Baglaenko, Peter K. Gregersen, Nikola Teslovich, Joerg Ermann, Soumya Raychaudhuri, Yang Luo, Kent D. Taylor
Publikováno v:
Nature genetics, vol 52, iss 3
Nature genetics
Nature Genetics
Nature genetics
Nature Genetics
Genetic studies have revealed that autoimmune susceptibility variants are over-represented in memory CD4+ T cell regulatory elements1–3. Understanding how genetic variation affects gene expression in different T cell physiological states is essenti
Autor:
V. Michael Holers, James R. O’Dell, Ashley Visser, Sonia Khatter, Kristen J. Polinski, Michael Mahler, Jill M. Norris, Ted R. Mikuls, Kevin D. Deane, Michael H. Weisman, M. Kristen Demoruelle, Heather M. Berens, Justin August, Jane H. Buckner, Richard M. Keating, Peter K. Gregersen
Publikováno v:
J Rheumatol
Objective.We investigated the association of age and anticyclic citrullinated peptide antibodies (anti-CCP) in subjects without rheumatoid arthritis (RA).Methods.Serum was tested for anti-CCP3.1 (IgG/IgA) in 678 first-degree relatives (FDR) of patien
Autor:
Patrick Concannon, Amy S. Shah, Linda S. Wicker, Suna Onengut-Gumuscu, Dana Dabelea, Chen W-M., Robert P. Kimberly, Jasmin Divers, David B. Dunger, Peter K. Gregersen, Jeffrey C. Edberg, Stephen S. Rich, Huan Yang, Santica M. Marcovina, Antony J. Cutler, S L Bridges, Marian Rewers, Carla J. Greenbaum, Flemming Pociot, Jorge R. Oksenberg, Jean M. Lawrence, Inshaw Jrj., D F Santa Cruz, Andrea K. Steck, Panagiotis Deloukas, Mark A. Atkinson, John A. Todd, Emily Farber, Crouch Djm., Jane H. Buckner, Catherine C. Robertson
Publikováno v:
Robertson, C C & Type 1 Diabetes Genetics Consortium 2021, ' Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes ', Nature Genetics, vol. 53, no. 7, pp. 962-971 . https://doi.org/10.1101/2020.06.19.158071, https://doi.org/10.1038/s41588-021-00880-5
Nature genetics
Nature genetics
We report the largest and most ancestrally diverse genetic study of type 1 diabetes (T1D) to date (61,427 participants), yielding 152 regions associated to false discovery rate < 0.01, including 36 regions associated to genome-wide significance for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a3f66533a4cf7a2a983554fd2421f8
https://curis.ku.dk/ws/files/284012839/2020.06.19.158071v1.full.pdf
https://curis.ku.dk/ws/files/284012839/2020.06.19.158071v1.full.pdf
Autor:
Meggan Mackay, Xinghao Wang, Richard Apps, Rishi R. Goel, Ashley Babyak, Valentina Giudice, Nathalia R Gazaniga, Betty Diamond, Ann Biehl, Martin P. Playford, Stephen R. Brooks, Katie Stagliano, Laura Vian, Peter K. Gregersen, Zerai Manna, Michael Davis, Shajia Lu, Elaine Poncio, Yinghui Shi, Nehal N. Mehta, Xiaobai Li, Yuri Kotliarov, Mohammad Naqi, Angelique Biancotto, Sarfaraz Hasni, Rongye Shi, Yenealem Temesgen-Oyelakin, Jinguo Chen, Donald E Thomas, Isabel Ochoa-Navas, Alan T. Remaley, Sarthak Gupta, Foo Cheung, Massimo Gadina, Huizhi Zhou, Wanxia Li Tsai, Philip M. Carlucci, John J. O'Shea, Mariana J. Kaplan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
Increased risk of premature cardiovascular disease (CVD) is well recognized in systemic lupus erythematosus (SLE). Aberrant type I-Interferon (IFN)-neutrophil interactions contribute to this enhanced CVD risk. In lupus animal models, the Janus kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee9ee9d9e4e4fc34a285087b8e0f4bc
http://hdl.handle.net/11386/4766268
http://hdl.handle.net/11386/4766268
Autor:
James R. O'Dell, V. Michael Holers, Kevin D. Deane, Jill M. Norris, Michael H. Weisman, M. Kristen Demoruelle, Kristen J. Polinski, Ted R. Mikuls, Jennifer Seifert, Jane H. Buckner, Elizabeth A. Bemis, Richard M. Keating, Peter K. Gregersen
Publikováno v:
Ann Rheum Dis
ObjectivesLittle is known about the likelihood of developing inflammatory arthritis (IA) in individuals who screen autoantibody positive (aAb+) in a non-clinical research setting.MethodsWe screened for serum cyclic citrullinated peptide antibody (ant