Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Peter J. Murray"'
Autor:
Rebecca Rosenthal, Christopher P. Jones, Adrian R. Ferré-D'Amaré, Peter J. Murray, Jaba Mitra, Taekjip Ha, Boyang Hua
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
RNAs begin to fold and function during transcription. Riboswitches undergo cotranscriptional switching in the context of transcription elongation, RNA folding, and ligand binding. To investigate how these processes jointly modulate the function of th
Autor:
Manuela Iezzi, Katia Donadello, Zheng-Li Shi, Stefano Ugel, Stefania Canè, Ying Chen, Marco Chilosi, Ido Amit, Peter J. Murray, Vincenzo Bronte, Francesca Hofer, Enrico Polati, Evelina Tacconelli, Piera Amelia Iezzi, Andrea Capece, Francesco De Sanctis, Alessandra Fiore, Francesco Domenico Del Pizzo, Leonardo Gottin, Serena Zilio, Silvio Bicciato, Chiara Musiu, Simone Caligola, Roza Maria Barouni, Alessia Lamolinara, Domenico Angelucci, Ildo Polidoro, Paolo Serafini, Cristina Frusteri, Andrea Grilli, Annalisa Adamo, Domenico Girelli
Publikováno v:
Cell Death and Differentiation
Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS),
Autor:
David Finkelstein, Marion Russier, Armita Bahrami, E. Kaitlynn Allen, Stephane Pelletier, Clifford S. Guy, Paul G. Thomas, Peter J. Murray, Taylor L. Wilson, Lee-Ann Van de Velde, Jeremy Chase Crawford, Leonie Zeitler, Stacey Schultz-Cherry
Publikováno v:
Cancer Res
Cancer Research
Cancer Research
Immune cells regulate tumor growth by mirroring their function as tissue repair organizers in normal tissues. To understand the different facets of immune–tumor collaboration through genetics, spatial transcriptomics, and immunologic manipulation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d603640d646946fa166d6deca221c7ba
https://mediatum.ub.tum.de/1639604
https://mediatum.ub.tum.de/1639604
Autor:
George Hajishengallis, Triantafyllos Chavakis, Sevina Dietz, Peter Mirtschink, Peter J. Murray, Athanasios Ziogas, Marina Nati, Kyoung-Jin Chung, Ioannis Kourtzelis, Ben Wielockx, Eman Hagag, Panayotis Verginis, Ales Neuwirth, Mihai G. Netea, Jonas Schulte-Schrepping, Ian Henry, Pallavi Subramanian, Joachim L. Schultze, Tatyana Grinenko, Canan Has, Antonios Chatzigeorgiou, Sundary Sormendi, Anupam Sinha, Ioannis Mitroulis, Xiaofei Li, Lydia Kalafati, Aikaterini Hatzioannou, Andreas Dahl, António Miguel de Jesus Domingues, Mathias Lesche
Publikováno v:
Cell, 183, 3, pp. 771-785.e12
Cell, 183, 771-785.e12
Cell 183(3), 771-785.e12 (2020). doi:10.1016/j.cell.2020.09.058
Cell
Kalafati, L, Kourtzelis, I, Schulte-Schrepping, J, Li, X, Hatzioannou, A, Grinenko, T, Hagag, E, Sinha, A, Has, C, Dietz, S, de Jesus Domingues, A M, Nati, M, Sormendi, S, Neuwirth, A, Chatzigeorgiou, A, Ziogas, A, Lesche, M, Dahl, A, Henry, I, Subramanian, P, Wielockx, B, Murray, P, Mirtschink, P, Chung, K-J, Schultze, J L, Netea, M G, Hajishengallis, G, Verginis, P, Mitroulis, I & Chavakis, T 2020, ' Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity ', Cell, vol. 183, no. 3, pp. 771-785 . https://doi.org/10.1016/j.cell.2020.09.058
Cell, 183, 771-785.e12
Cell 183(3), 771-785.e12 (2020). doi:10.1016/j.cell.2020.09.058
Cell
Kalafati, L, Kourtzelis, I, Schulte-Schrepping, J, Li, X, Hatzioannou, A, Grinenko, T, Hagag, E, Sinha, A, Has, C, Dietz, S, de Jesus Domingues, A M, Nati, M, Sormendi, S, Neuwirth, A, Chatzigeorgiou, A, Ziogas, A, Lesche, M, Dahl, A, Henry, I, Subramanian, P, Wielockx, B, Murray, P, Mirtschink, P, Chung, K-J, Schultze, J L, Netea, M G, Hajishengallis, G, Verginis, P, Mitroulis, I & Chavakis, T 2020, ' Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity ', Cell, vol. 183, no. 3, pp. 771-785 . https://doi.org/10.1016/j.cell.2020.09.058
Summary Trained innate immunity, induced via modulation of mature myeloid cells or their bone marrow progenitors, mediates sustained increased responsiveness to secondary challenges. Here, we investigated whether anti-tumor immunity can be enhanced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c637a504dcda3e4fee30ef1cda9f210
https://hdl.handle.net/2066/228705
https://hdl.handle.net/2066/228705
Autor:
Peter J. Murray, Joseph E. Qualls
Publikováno v:
Seminars in Immunopathology. 38:139-152
Tuberculosis (TB) granulomas are compact, organized agglomerations of infected and uninfected macrophages, T cells, neutrophils, and other immune cells. Within the granuloma, several unique metabolic adaptations occur to modify the behavior of immune
Autor:
Franz Kratochvill, Geoffrey Neale, Jessica M. Haverkamp, Daisuke Kawauchi, Amber M. Smith, Lee Ann Van de Velde, Michael A. Dyer, Justina McEvoy, Martine F. Roussel, Joseph E. Qualls, Peter J. Murray
Publikováno v:
Cell Reports, Vol 12, Iss 11, Pp 1902-1914 (2015)
SummaryCancer can involve non-resolving, persistent inflammation where varying numbers of tumor-associated macrophages (TAMs) infiltrate and adopt different activation states between anti-tumor M1 and pro-tumor M2 phenotypes. Here, we resolve a casca
Autor:
Michael J. Korrer, Peter J. Murray, Young J. Kim, David L. Masica, Qi Zeng, Mikhail Gorbounov, Juan Fu, Drew M. Pardoll
Publikováno v:
Cancer Immunol Res
Immunosuppressive myeloid-derived suppressive cells (MDSCs) are characterized by their phenotypic and functional heterogeneity. To better define their T cell–independent functions within the tumor, sorted monocytic CD14+CD11b+HLA-DRlow/– MDSCs (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c63beeab6690a2a40cb538d7bce210
https://europepmc.org/articles/PMC9336537/
https://europepmc.org/articles/PMC9336537/
Autor:
Alessia Lamolinara, Davide Melisi, Peter J. Murray, Aldo Scarpa, Manuela Iezzi, Giulio Fracasso, Samantha Solito, Carmine Carbone, Fulvia Vascotto, Silvio Bicciato, Bruce R. Blazar, Francesco De Sanctis, Alessandra Fiore, Geny Piro, Ugur Sahin, Giada Mondanelli, Sara Sandri, Vincenzo Bronte, Matteo Fassan, Keli L. Hippen, Stefano Ugel, Rosalinda Trovato, Silvia Sartoris, Ursula Grohmann, Rita T. Lawlor, Susanna Mandruzzato
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Immunosuppression is a hallmark of tumor progression, and treatments that inhibit or deplete monocytic myeloid-derived suppressive cells could promote anti-tumor immunity. c-FLIP is a central regulator of caspase-8-mediated apoptosis and necroptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfd4cc18c28c69f032a589433baa975
http://hdl.handle.net/11577/3283867
http://hdl.handle.net/11577/3283867
Autor:
Nina Gratz, Franz Kratochvill, Pavel Kovarik, Hongbo Chi, Lee-Ann Van de Velde, Peter J. Murray, Joseph E. Qualls
Publikováno v:
Cancer Research. 75:3054-3064
Tristetraprolin (TTP) is an inducible zinc finger AU-rich RNA-binding protein essential for enforcing degradation of mRNAs encoding inflammatory chemokines and cytokines. Most studies on TTP center on the connection between mRNA half-life and inflamm
Autor:
Tiffany A. Reese, Gautam Goel, Maxim N. Artyomov, Stanley Ching-Cheng Huang, Samuel H. Speck, Catherine Y. Liu, Matthew M. Hufford, Andrew J. Jezewski, Xin Zhang, Michael D. Buck, Brian S. Wakeman, Mark H. Kaplan, Edward J. Pearce, Ramnik J. Xavier, Rolf Renne, Amal Kambal, Peter J. Murray, H.S. Choi, Herbert W. Virgin
Publikováno v:
Science
Parasites make it hard to fight viruses Microbial co-infections challenge the immune system—different pathogens often require different flavors of immune responses for their elimination or containment (see the Perspective by Maizels and Gause). Two