Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Michael, Gill"'
Autor:
Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., Holmans, P. A., Boland, A., Damotte, V., van der Lee, S. J., Costa, M. R., Kuulasmaa, T., Yang, Q., de Rojas, I., Bis, J. C., Yaqub, A., Prokic, I., Chapuis, J., Ahmad, S., Giedraitis, V., Aarsland, D., Garcia-Gonzalez, P., Abdelnour, C., Alarcón-Martín, E., Alcolea, D., Alegret, M., Alvarez, I., Álvarez, V., Armstrong, N. J., Tsolaki, A., Antúnez, C., Appollonio, I., Arcaro, M., Archetti, S., Pastor, A. A., Arosio, B., Athanasiu, L., Bailly, H., Banaj, N., Baquero, M., Barral, S., Beiser, A., Pastor, A. B., Below, J. E., Benchek, P., Benussi, L., Berr, C., Besse, C., Bessi, V., Binetti, G., Bizarro, A., Blesa, R., Boada, M., Boerwinkle, E., Borroni, B., Boschi, S., Bossù, P., Bråthen, G., Bressler, J., Bresner, C., Brodaty, H., Brookes, K. J., Brusco, L. I., Buiza-Rueda, D., Bûrger, K., Burholt, V., Bush, W. S., Calero, M., Cantwell, L. B., Chene, G., Chung, J., Cuccaro, M. L., Carracedo, Á., Cecchetti, R., Cervera-Carles, L., Charbonnier, C., Chen, H. -H., Chillotti, C., Ciccone, S., Claassen, J. A. H. R., Clark, C., Conti, E., Corma-Gómez, A., Costantini, E., Custodero, C., Daian, D., Dalmasso, M. C., Daniele, A., Dardiotis, E., Dartigues, J. -F., de Deyn, P. P., de Paiva Lopes, K., de Witte, L. D., Debette, S., Deckert, J., del Ser, T., Denning, N., Destefano, A., Dichgans, M., Diehl-Schmid, J., Diez-Fairen, M., Rossi, P. D., Djurovic, S., Duron, E., Düzel, E., Dufouil, C., Eiriksdottir, G., Engelborghs, S., Escott-Price, V., Espinosa, A., Ewers, M., Faber, K. M., Fabrizio, T., Nielsen, S. F., Fardo, D. W., Farotti, L., Fenoglio, C., Fernández-Fuertes, M., Ferrari, R., Ferreira, C. B., Ferri, E., Fin, B., Fischer, P., Fladby, T., Fließbach, K., Fongang, B., Fornage, M., Fortea, J., Foroud, T. M., Fostinelli, S., Fox, N. C., Franco-Macías, E., Bullido, M. J., Frank-García, A., Froelich, L., Fulton-Howard, B., Galimberti, D., García-Alberca, J. M., García-González, P., Garcia-Madrona, S., Garcia-Ribas, G., Ghidoni, R., Giegling, I., Giorgio, G., Goate, A. M., Goldhardt, O., Gomez-Fonseca, D., González-Pérez, A., Graff, C., Grande, G., Green, E., Grimmer, T., Grünblatt, E., Grunin, M., Gudnason, V., Guetta-Baranes, T., Haapasalo, A., Hadjigeorgiou, G., Haines, J. L., Hamilton-Nelson, K. L., Hampel, H., Hanon, O., Hardy, J., Hartmann, A. M., Hausner, L., Harwood, J., Heilmann-Heimbach, S., Helisalmi, S., Heneka, M. T., Hernández, I., Herrmann, M. J., Hoffmann, P., Holmes, C., Holstege, H., Vilas, R. H., Hulsman, M., Humphrey, J., Biessels, G. J., Jian, X., Johansson, C., Jun, G. R., Kastumata, Y., Kauwe, J., Kehoe, P. G., Kilander, L., Ståhlbom, A. K., Kivipelto, M., Koivisto, A., Kornhuber, J., Kosmidis, M. H., Kukull, W. A., Kuksa, P. P., Kunkle, B. W., Kuzma, A. B., Lage, C., Laukka, E. J., Launer, L., Lauria, A., Lee, C. -Y., Lehtisalo, J., Lerch, O., Lleó, A., Longstreth, W., Lopez, O., de Munain, A. L., Love, S., Löwemark, M., Luckcuck, L., Lunetta, K. L., Ma, Y., Macías, J., Macleod, C. A., Maier, W., Mangialasche, F., Spallazzi, M., Marquié, M., Marshall, R., Martin, E. R., Montes, A. M., Rodríguez, C. M., Masullo, C., Mayeux, R., Mead, S., Mecocci, P., Medina, M., Meggy, A., Mehrabian, S., Mendoza, S., Menéndez-González, M., Mir, P., Moebus, S., Mol, M., Molina-Porcel, L., Montrreal, L., Morelli, L., Moreno, F., Morgan, K., Mosley, T., Nöthen, M. M., Muchnik, C., Mukherjee, S., Nacmias, B., Ngandu, T., Nicolas, G., Nordestgaard, B. G., Olaso, R., Orellana, A., Orsini, M., Ortega, G., Padovani, A., Paolo, C., Papenberg, G., Parnetti, L., Pasquier, F., Pastor, P., Peloso, G., Pérez-Cordón, A., Pérez-Tur, J., Pericard, P., Peters, O., Pijnenburg, Y. A. L., Pineda, J. A., Piñol-Ripoll, G., Pisanu, C., Polak, T., Popp, J., Posthuma, D., Priller, J., Puerta, R., Quenez, O., Quintela, I., Thomassen, J. Q., Rábano, A., Rainero, I., Rajabli, F., Ramakers, I., Real, L. M., Reinders, M. J. T., Reitz, C., Reyes-Dumeyer, D., Ridge, P., Riedel-Heller, S., Riederer, P., Roberto, N., Rodriguez-Rodriguez, E., Rongve, A., Allende, I. R., Rosende-Roca, M., Royo, J. L., Rubino, E., Rujescu, D., Sáez, M. E., Sakka, P., Saltvedt, I., Sanabria, Á., Sánchez-Arjona, M. B., Sanchez-Garcia, F., Juan, P. S., Sánchez-Valle, R., Sando, S. B., Sarnowski, C., Satizabal, C. L., Scamosci, M., Scarmeas, N., Scarpini, E., Scheltens, P., Scherbaum, N., Scherer, M., Schmid, M., Schneider, A., Schott, J. M., Selbæk, G., Seripa, D., Serrano, M., Sha, J., Shadrin, A. A., Skrobot, O., Slifer, S., Snijders, G. J. L., Soininen, H., Solfrizzi, V., Solomon, A., Song, Y. E., Sorbi, S., Sotolongo-Grau, O., Spalletta, G., Spottke, A., Squassina, A., Stordal, E., Tartan, J. P., Tárraga, L., Tesí, N., Thalamuthu, A., Thomas, T., Tosto, G., Traykov, L., Tremolizzo, L., Tybjærg-Hansen, A., Uitterlinden, A., Ullgren, A., Ulstein, I., Valero, S., Valladares, O., Broeckhoven, C. V., Vance, J., Vardarajan, B. N., van der Lugt, A., Dongen, J. V., van Rooij, J., van Swieten, J., Vandenberghe, R., Verhey, F., Vidal, J. -S., Vogelgsang, J., Vyhnalek, M., Wagner, M., Wallon, D., Wang, L. -S., Wang, R., Weinhold, L., Wiltfang, J., Windle, G., Woods, B., Yannakoulia, M., Zare, H., Zhao, Y., Zhang, X., Zhu, C., Zulaica, M., Laczo, J., Matoska, V., Serpente, M., Assogna, F., Piras, F., Ciullo, V., Shofany, J., Ferrarese, C., Andreoni, S., Sala, G., Zoia, C. P., Zompo, M. D., Benussi, A., Bastiani, P., Takalo, M., Natunen, T., Laatikainen, T., Tuomilehto, J., Antikainen, R., Strandberg, T., Lindström, J., Peltonen, M., Abraham, R., Al-Chalabi, A., Bass, N. J., Brayne, C., Brown, K. S., Collinge, J., Craig, D., Deloukas, P., Fox, N., Gerrish, A., Gill, M., Gwilliam, R., Harold, D., Hollingworth, P., Johnston, J. A., Jones, L., Lawlor, B., Livingston, G., Lovestone, S., Lupton, M., Lynch, A., Mann, D., Mcguinness, B., Mcquillin, A., O’Donovan, M. C., Owen, M. J., Passmore, P., Powell, J. F., Proitsi, P., Rossor, M., Shaw, C. E., Smith, A. D., Gurling, H., Todd, S., Mummery, C., Ryan, N., Lacidogna, G., Adarmes-Gómez, A., Mauleón, A., Pancho, A., Gailhajenet, A., Lafuente, A., Macias-García, D., Martín, E., Pelejà, E., Carrillo, F., Merlín, I. S., Garrote-Espina, L., Vargas, L., Carrion-Claro, M., Marín, M., Labrador, M., Buendia, M., Alonso, M. D., Guitart, M., Moreno, M., Ibarria, M., Periñán, M., Aguilera, N., Gómez-Garre, P., Cañabate, P., Escuela, R., Pineda-Sánchez, R., Vigo-Ortega, R., Jesús, S., Preckler, S., Rodrigo-Herrero, S., Diego, S., Vacca, A., Roveta, F., Salvadori, N., Chipi, E., Boecker, H., Laske, C., Perneczky, R., Anastasiou, C., Janowitz, D., Malik, R., Anastasiou, A., Parveen, K., López-García, S., Antonell, A., Mihova, K. Y., Belezhanska, D., Weber, H., Kochen, S., Solis, P., Medel, N., Lisso, J., Sevillano, Z., Politis, D. G., Cores, V., Cuesta, C., Ortiz, C., Bacha, J. I., Rios, M., Saenz, A., Abalos, M. S., Kohler, E., Palacio, D. L., Etchepareborda, I., Kohler, M., Novack, G., Prestia, F. A., Galeano, P., Castaño, E. M., Germani, S., Toso, C. R., Rojo, M., Ingino, C., Mangone, C., Rubinsztein, D. C., Teipel, S., Fievet, N., Deramerourt, V., Forsell, C., Thonberg, H., Bjerke, M., Roeck, E. D., Martínez-Larrad, M. T., Olivar, N., Cano, A., Macias, J., Maroñas, O., Nuñez-Llaves, R., Olivé, C., Adarmes-Gómez, A. D., Amer-Ferrer, G., Antequera, M., Burguera, J. A., Casajeros, M. J., Martinez de Pancorbo, M., Hevilla, S., Espinosa, M. A. L., Legaz, A., Manzanares, S., Marín-Muñoz, J., Marín, T., Martínez, B., Martínez, V., Martínez-Lage Álvarez, P., Iriarte, M. M., Periñán-Tocino, M. T., Real de Asúa, D., Rodrigo, S., Sastre, I., Vicente, M. P., Vivancos, L., Epelbaum, J., Hannequin, D., Campion, D., Deramecourt, V., Tzourio, C., Brice, A., Dubois, B., Williams, A., Thomas, C., Davies, C., Nash, W., Dowzell, K., Morales, A. C., Bernardo-Harrington, M., Turton, J., Lord, J., Brown, K., Vardy, E., Fisher, E., Warren, J. D., Ryan, N. S., Guerreiro, R., Uphill, J., Bass, N., Heun, R., Kölsch, H., Schürmann, B., Lacour, A., Herold, C., Powell, J., Patel, Y., Hodges, A., Becker, T., Warden, D., Wilcock, G., Clarke, R., Ben-Shlomo, Y., Hooper, N. M., Pickering-Brown, S., Sussams, R., Warner, N., Bayer, A., Heuser, I., Drichel, D., Klopp, N., Mayhaus, M., Riemenschneider, M., Pinchler, S., Feulner, T., Gu, W., van den Bussche, H., Hüll, M., Frölich, L., Wichmann, H. -E., Jöckel, K. -H., O’Donovan, M., Owen, M., Bahrami, S., Bosnes, I., Selnes, P., Bergh, S., Palotie, A., Daly, M., Jacob, H., Matakidou, A., Runz, H., John, S., Plenge, R., Mccarthy, M., Hunkapiller, J., Ehm, M., Waterworth, D., Fox, C., Malarstig, A., Klinger, K., Call, K., Behrens, T., Loerch, P., Mäkelä, T., Kaprio, J., Virolainen, P., Pulkki, K., Kilpi, T., Perola, M., Partanen, J., Pitkäranta, A., Kaarteenaho, R., Vainio, S., Turpeinen, M., Serpi, R., Laitinen, T., Mäkelä, J., Kosma, V. -M., Kujala, U., Tuovila, O., Hendolin, M., Pakkanen, R., Waring, J., Riley-Gillis, B., Liu, J., Biswas, S., Diogo, D., Marshall, C., Hu, X., Gossel, M., Graham, R., Cummings, B., Ripatti, S., Schleutker, J., Arvas, M., Carpén, O., Hinttala, R., Kettunen, J., Mannermaa, A., Laukkanen, J., Julkunen, V., Remes, A., Kälviäinen, R., Peltola, J., Tienari, P., Rinne, J., Ziemann, A., Esmaeeli, S., Smaoui, N., Lehtonen, A., Eaton, S., Lahdenperä, S., van Adelsberg, J., Michon, J., Kerchner, G., Bowers, N., Teng, E., Eicher, J., Mehta, V., Gormley, P., Linden, K., Whelan, C., Xu, F., Pulford, D., Färkkilä, M., Pikkarainen, S., Jussila, A., Blomster, T., Kiviniemi, M., Voutilainen, M., Georgantas, B., Heap, G., Rahimov, F., Usiskin, K., Lu, T., Oh, D., Kalpala, K., Miller, M., Mccarthy, L., Eklund, K., Palomäki, A., Isomäki, P., Pirilä, L., Kaipiainen-Seppänen, O., Huhtakangas, J., Lertratanakul, A., Hochfeld, M., Bing, N., Gordillo, J. E., Mars, N., Pelkonen, M., Kauppi, P., Kankaanranta, H., Harju, T., Close, D., Greenberg, S., Chen, H., Betts, J., Ghosh, S., Salomaa, V., Niiranen, T., Juonala, M., Metsärinne, K., Kähönen, M., Junttila, J., Laakso, M., Pihlajamäki, J., Sinisalo, J., Taskinen, M. -R., Tuomi, T., Challis, B., Peterson, A., Chu, A., Parkkinen, J., Muslin, A., Joensuu, H., Meretoja, T., Aaltonen, L., Mattson, J., Auranen, A., Karihtala, P., Kauppila, S., Auvinen, P., Elenius, K., Popovic, R., Schutzman, J., Loboda, A., Chhibber, A., Lehtonen, H., Mcdonough, S., Crohns, M., Kulkarni, D., Kaarniranta, K., Turunen, J. A., Ollila, T., Seitsonen, S., Uusitalo, H., Aaltonen, V., Uusitalo-Järvinen, H., Luodonpää, M., Hautala, N., Loomis, S., Strauss, E., Podgornaia, A., Hoffman, J., Tasanen, K., Huilaja, L., Hannula-Jouppi, K., Salmi, T., Peltonen, S., Koulu, L., Harvima, I., Wu, Y., Choy, D., Pussinen, P., Salminen, A., Salo, T., Rice, D., Nieminen, P., Palotie, U., Siponen, M., Suominen, L., Mäntylä, P., Gursoy, U., Anttonen, V., Sipilä, K., Davis, J. W., Quarless, D., Petrovski, S., Wigmore, E., Chen, C. -Y., Bronson, P., Tsai, E., Huang, Y., Maranville, J., Shaikho, E., Mohammed, E., Wadhawan, S., Kvikstad, E., Caliskan, M., Chang, D., Bhangale, T., Pendergrass, S., Holzinger, E., Chen, X., Hedman, Å., King, K. S., Wang, C., Xu, E., Auge, F., Chatelain, C., Rajpal, D., Liu, D., Xia, T. -H., Brauer, M., Kurki, M., Karjalainen, J., Havulinna, A., Jalanko, A., Palta, P., della Briotta Parolo, P., Zhou, W., Lemmelä, S., Rivas, M., Harju, J., Lehisto, A., Ganna, A., Llorens, V., Laivuori, H., Rüeger, S., Niemi, M. E., Tukiainen, T., Reeve, M. P., Heyne, H., Palin, K., Garcia-Tabuenca, J., Siirtola, H., Kiiskinen, T., Lee, J., Tsuo, K., Elliott, A., Kristiansson, K., Hyvärinen, K., Ritari, J., Koskinen, M., Pylkäs, K., Kalaoja, M., Karjalainen, M., Mantere, T., Kangasniemi, E., Heikkinen, S., Laakkonen, E., Sipeky, C., Heron, S., Karlsson, A., Jambulingam, D., Rathinakannan, V. S., Kajanne, R., Aavikko, M., Jiménez, M. G., della Briotta Parola, P., Kanai, M., Kaunisto, M., Kilpeläinen, E., Sipilä, T. P., Brein, G., Awaisa, G., Shcherban, A., Donner, K., Loukola, A., Laiho, P., Sistonen, T., Kaiharju, E., Laukkanen, M., Järvensivu, E., Lähteenmäki, S., Männikkö, L., Wong, R., Mattsson, H., Hiekkalinna, T., Paajanen, T., Pärn, K., Gracia-Tabuenca, J., Abner, E., Adams, P. M., Aguirre, A., Albert, M. S., Albin, R. L., Allen, M., Alvarez, L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Ayres, G., Baldwin, C. T., Barber, R. C., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Benitez, B. A., Bennett, D., Bertelson, J., Margaret, F. E., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Brewer, J., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Chasse, S., Chesselet, M. -F., Chesi, A., Chin, N. A., Chui, H. C., Craft, S., Crane, P. K., Cribbs, D. H., Crocco, E. A., Cruchaga, C., Cullum, M., Darby, E., Davis, B., De Jager, P. L., Decarli, C., Detoledo, J., Dick, M., Dickson, D. W., Dombroski, B. A., Doody, R. S., Duara, R., Ertekin-Taner, N., Evans, D. A., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Farrell, J. J., Fernandez-Hernandez, V., Ferris, S., Frosch, M. P., Galasko, D. R., Gamboa, A., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Grabowski, T. J., Graff-Radford, N. R., Grant, S. F. A., Green, R. C., Growdon, J. H., Hakonarson, H., Hall, J., Hamilton, R. L., Harari, O., Harrell, L. E., Haut, J., Head, E., Henderson, V. W., Hernandez, M., Hohman, T., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Hynan, L. S., Ibanez, L., Jarvik, G. P., Jayadev, S., Jin, L. -W., Johnson, K., Johnson, L., Kamboh, M. I., Karydas, A. M., Katz, M. J., Kaye, J. A., Keene, C. D., Khaleeq, A., Kim, R., Knebl, J., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Larson, E. B., Lee, E. B., Lerner, A., Leung, Y. Y., Leverenz, J. B., Levey, A. I., Li, M., Lieberman, A. P., Lipton, R. B., Logue, M., Lyketsos, C. G., Malamon, J., Mains, D., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., Massman, P., Masurkar, A., Mccormick, W. C., Mccurry, S. M., Mcdavid, A. N., Mckee, A. C., Mesulam, M., Mez, J., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Monuki, E. S., Morris, J. C., Myers, A. J., Nguyen, T., O’Bryant, S., Olichney, J. M., Ory, M., Palmer, R., Parisi, J. E., Paulson, H. L., Pavlik, V., Paydarfar, D., Perez, V., Peskind, E., Petersen, R. C., Phillips-Cremins, J. E., Pierce, A., Polk, M., Poon, W. W., Potter, H., Qu, L., Quiceno, M., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reisch, J. S., Ringman, J. M., Roberson, E. D., Rodriguear, M., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Small, S., Smith, A. G., Smith, J. P., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Stevens, A. B., Strittmatter, S. M., Sultzer, D., Swerdlow, R. H., Tanzi, R. E., Tilson, J. L., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., van Eldik, L. J., Vassar, R., Vinters, H. V., Vonsattel, J. -P., Weintraub, S., Welsh-Bohmer, K. A., Whitehead, P. L., Wijsman, E. M., Wilhelmsen, K. C., Williams, B., Williamson, J., Wilms, H., Wingo, T. S., Wisniewski, T., Woltjer, R. L., Woon, M., Wright, C. B., C. -K., Wu, Younkin, S. G., C. -E., Yu, Yu, L., Zhang, Y., Zhu, X., Adams, H., Akinyemi, R. O., Ali, M., Armstrong, N., Aparicio, H. J., Bahadori, M., Breteler, M., Chasman, D., Chauhan, G., Comic, H., Cox, S., Cupples, A. L., Davies, G., Decarli, C. S., Duperron, M. -G., Dupuis, J., Evans, T., Fan, F., Fitzpatrick, A., Fohner, A. E., Ganguli, M., Geerlings, M., Glatt, S. J., Gonzalez, H. M., Goss, M., Grabe, H., Habes, M., Heckbert, S. R., Hofer, E., Hong, E., Hughes, T., Kautz, T. F., Knol, M., Kremen, W., Lacaze, P., Lahti, J., Grand, Q. L., Litkowski, E., Li, S., Liu, X., Loitfelder, M., Manning, A., Maillard, P., Marioni, R., Mazoyer, B., van Lent, D. M., Mei, H., Mishra, A., Nyquist, P., O’Connell, J., Paus, T., Pausova, Z., Raikkonen-Talvitie, K., Riaz, M., Rich, S., Rotter, J., Romero, J., Roshchupkin, G., Saba, Y., Sargurupremraj, M., Schmidt, H., Schmidt, R., Shulman, J. M., Smith, J., Sekhar, H., Rajula, R., Shin, J., Simino, J., Sliz, E., Teumer, A., Thomas, A., Tin, A., Tucker-Drob, E., Vojinovic, D., Wang, Y., Weinstein, G., Williams, D., Wittfeld, K., Yanek, L., Yang, Y., Farrer, L. A., Psaty, B. M., Ghanbari, M., Raj, T., Sachdev, P., Mather, K., Jessen, F., Ikram, M. A., de Mendonça, A., Hort, J., Tsolaki, M., Pericak-Vance, M. A., Amouyel, P., Williams, J., Frikke-Schmidt, R., Clarimon, J., Deleuze, J. -F., Rossi, G., Seshadri, S., Andreassen, O. A., Ingelsson, M., Hiltunen, M., Sleegers, K., Schellenberg, G. D., van Duijn, C. M., Sims, R., van der Flier, W. M., Ruiz, A., Ramirez, A., Lambert J., -C, Jan, Laczo, Vaclav, Matoska, Maria, Serpente, Francesca, Assogna, Fabrizio, Piras, Federica, Piras, Valentina, Ciullo, Jacob, Shofany, Carlo, Ferrarese, Simona, Andreoni, Gessica, Sala, Chiara Paola Zoia, Maria Del Zompo, Benussi, Alberto, Patrizia, Bastiani, Mari, Takalo, Teemu, Natunen, Tiina, Laatikainen, Jaakko, Tuomilehto, Riitta, Antikainen, Timo, Strandberg, Jaana, Lindström, Markku, Peltonen, Richard, Abraham, Ammar, Al-Chalabi, Nicholas, J Bass, Carol, Brayne, Kristelle, S Brown, John, Collinge, David, Craig, Pangiotis, Deloukas, Nick, Fox, Amy, Gerrish, Michael, Gill, Rhian, Gwilliam, Denise, Harold, Paul, Hollingworth, Jarret, A Johnston, Lesley, Jones, Brian, Lawlor, Gill, Livingston, Simon, Lovestone, Michelle, Lupton, Aoibhinn, Lynch, David, Mann, Bernadette, Mcguinness, Andrew, Mcquillin, Michael, C O'Donovan, Michael, J Owen, Peter, Passmore, John, F Powell, Petra, Proitsi, Martin, Rossor, Christopher, E Shaw, A David Smith, 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Publikováno v:
EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Nature Genetics, 54(4), 412-436. Nature Publishing Group
Nature Genetics, 54(4)
Nature genetics, 54(4), 412-436. Nature Publishing Group
Nature Genetics, 54, 4, pp. 412-436
Nature Genetics
Nature Genetics, 54, 412-436
NATURE GENETICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Digital.CSIC. Repositorio Institucional del CSIC
EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Nature genetics
2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature genetics 54(4), 412-436 (2022). doi:10.1038/s41588-022-01024-z
Bellenguez, C, Küçükali, F, Jansen, I E, Kleineidam, L, Moreno-Grau, S, Amin, N, Naj, A C, Campos-Martin, R, Grenier-Boley, B, Andrade, V, Holmans, P A, Boland, A, Damotte, V, van der Lee, S J, Costa, M R, Kuulasmaa, T, Yang, Q, de Rojas, I, Bis, J C, Yaqub, A, Prokic, I, Chapuis, J, Ahmad, S, Giedraitis, V, Aarsland, D, Garcia-Gonzalez, P, Abdelnour, C, Alarcón-Martín, E, Alcolea, D, Alegret, M, Alvarez, I, Álvarez, V, Armstrong, N J, Tsolaki, A, Antúnez, C, Appollonio, I, Arcaro, M, Archetti, S, Pastor, A A, Arosio, B, Athanasiu, L, Bailly, H, Banaj, N, Baquero, M, Barral, S, Beiser, A, Nielsen, S F, Nordestgaard, B G, Sáez, M E, Frikke-Schmidt, R, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Nature Genetics, 54(4), 412-436. Nature Publishing Group
Nature Genetics, 54(4)
Nature genetics, 54(4), 412-436. Nature Publishing Group
Nature Genetics, 54, 4, pp. 412-436
Nature Genetics
Nature Genetics, 54, 412-436
NATURE GENETICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Digital.CSIC. Repositorio Institucional del CSIC
EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Nature genetics
2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature genetics 54(4), 412-436 (2022). doi:10.1038/s41588-022-01024-z
Bellenguez, C, Küçükali, F, Jansen, I E, Kleineidam, L, Moreno-Grau, S, Amin, N, Naj, A C, Campos-Martin, R, Grenier-Boley, B, Andrade, V, Holmans, P A, Boland, A, Damotte, V, van der Lee, S J, Costa, M R, Kuulasmaa, T, Yang, Q, de Rojas, I, Bis, J C, Yaqub, A, Prokic, I, Chapuis, J, Ahmad, S, Giedraitis, V, Aarsland, D, Garcia-Gonzalez, P, Abdelnour, C, Alarcón-Martín, E, Alcolea, D, Alegret, M, Alvarez, I, Álvarez, V, Armstrong, N J, Tsolaki, A, Antúnez, C, Appollonio, I, Arcaro, M, Archetti, S, Pastor, A A, Arosio, B, Athanasiu, L, Bailly, H, Banaj, N, Baquero, M, Barral, S, Beiser, A, Nielsen, S F, Nordestgaard, B G, Sáez, M E, Frikke-Schmidt, R, EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE 2022, ' New insights into the genetic etiology of Alzheimer's disease and related dementias ', Nature Genetics, vol. 54, no. 4, pp. 412-436 . https://doi.org/10.1038/s41588-022-01024-z
25 páginas, 6 figuras, 2 tablas
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We perfor
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We perfor
Autor:
Gabriëlla A.M. Blokland, Jakob Grove, Chia-Yen Chen, Chris Cotsapas, Stuart Tobet, Robert Handa, David St Clair, Todd Lencz, Bryan J. Mowry, Sathish Periyasamy, Murray J. Cairns, Paul A. Tooney, Jing Qin Wu, Brian Kelly, George Kirov, Patrick F. Sullivan, Aiden Corvin, Brien P. Riley, Tõnu Esko, Lili Milani, Erik G. Jönsson, Aarno Palotie, Hannelore Ehrenreich, Martin Begemann, Agnes Steixner-Kumar, Pak C. Sham, Nakao Iwata, Daniel R. Weinberger, Pablo V. Gejman, Alan R. Sanders, Joseph D. Buxbaum, Dan Rujescu, Ina Giegling, Bettina Konte, Annette M. Hartmann, Elvira Bramon, Robin M. Murray, Michele T. Pato, Jimmy Lee, Ingrid Melle, Espen Molden, Roel A. Ophoff, Andrew McQuillin, Nicholas J. Bass, Rolf Adolfsson, Anil K. Malhotra, Nicholas G. Martin, Janice M. Fullerton, Philip B. Mitchell, Peter R. Schofield, Andreas J. Forstner, Franziska Degenhardt, Sabrina Schaupp, Ashley L. Comes, Manolis Kogevinas, José Guzman-Parra, Andreas Reif, Fabian Streit, Lea Sirignano, Sven Cichon, Maria Grigoroiu-Serbanescu, Joanna Hauser, Jolanta Lissowska, Fermin Mayoral, Bertram Müller-Myhsok, Beata Świątkowska, Thomas G. Schulze, Markus M. Nöthen, Marcella Rietschel, John Kelsoe, Marion Leboyer, Stéphane Jamain, Bruno Etain, Frank Bellivier, John B. Vincent, Martin Alda, Claire O’Donovan, Pablo Cervantes, Joanna M. Biernacka, Mark Frye, Susan L. McElroy, Laura J. Scott, Eli A. Stahl, Mikael Landén, Marian L. Hamshere, Olav B. Smeland, Srdjan Djurovic, Arne E. Vaaler, Ole A. Andreassen, Bernhard T. Baune, Tracy Air, Martin Preisig, Rudolf Uher, Douglas F. Levinson, Myrna M. Weissman, James B. Potash, Jianxin Shi, James A. Knowles, Roy H. Perlis, Susanne Lucae, Dorret I. Boomsma, Brenda W.J.H. Penninx, Jouke-Jan Hottenga, Eco J.C. de Geus, Gonneke Willemsen, Yuri Milaneschi, Henning Tiemeier, Hans J. Grabe, Alexander Teumer, Sandra Van der Auwera, Uwe Völker, Steven P. Hamilton, Patrik K.E. Magnusson, Alexander Viktorin, Divya Mehta, Niamh Mullins, Mark J. Adams, Gerome Breen, Andrew M. McIntosh, Cathryn M. Lewis, David M. Hougaard, Merete Nordentoft, Ole Mors, Preben B. Mortensen, Thomas Werge, Thomas D. Als, Anders D. Børglum, Tracey L. Petryshen, Jordan W. Smoller, Jill M. Goldstein, Stephan Ripke, Benjamin M. Neale, James T.R. Walters, Kai-How Farh, Peter A. Holmans, Phil Lee, Brendan Bulik-Sullivan, David A. Collier, Hailiang Huang, Tune H. Pers, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Silviu A. Bacanu, Richard A. Belliveau, Judit Bene, Sarah E. Bergen, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, William Byerley, Wiepke Cahn, Guiqing Cai, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberly D. Chambert, Raymond C.K. Chan, Ronald Y.L. Chen, Eric Y.H. Chen, Wei Cheng, Eric F.C. Cheung, Siow Ann Chong, C. Robert Cloninger, David Cohen, Nadine Cohen, Paul Cormican, Nick Craddock, James J. Crowley, David Curtis, Michael Davidson, Kenneth L. Davis, Jurgen Del Favero, Ditte Demontis, Dimitris Dikeos, Timothy Dinan, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Naser Durmishi, Peter Eichhammer, Johan Eriksson, Valentina Escott-Price, Laurent Essioux, Ayman H. Fanous, Martilias S. Farrell, Josef Frank, Lude Franke, Robert Freedman, Nelson B. Freimer, Marion Friedl, Joseph I. Friedman, Menachem Fromer, Giulio Genovese, Lyudmila Georgieva, Paola Giusti-Rodríguez, Stephanie Godard, Jacqueline I. Goldstein, Vera Golimbet, Srihari Gopal, Jacob Gratten, Lieuwe de Haan, Christian Hammer, Mark Hansen, Thomas Hansen, Vahram Haroutunian, Frans A. Henskens, Stefan Herms, Joel N. Hirschhorn, Per Hoffmann, Andrea Hofman, Mads V. Hollegaard, Masashi Ikeda, Inge Joa, Antonio Julià, René S. Kahn, Luba Kalaydjieva, Sena Karachanak-Yankova, Juha Karjalainen, David Kavanagh, Matthew C. Keller, James L. Kennedy, Andrey Khrunin, Yunjung Kim, Janis Klovins, Vaidutis Kucinskas, Zita Ausrele Kucinskiene, Hana Kuzelova-Ptackova, Anna K. Kähler, Claudine Laurent, Jimmy Lee Chee Keong, S. Hong Lee, Sophie E. Legge, Bernard Lerer, Miaoxin Li, Tao Li, Kung-Yee Liang, Jeffrey Lieberman, Svetlana Limborska, Carmel M. Loughland, Jan Lubinski, Jouko Lönnqvist, Milan Macek, Brion S. Maher, Wolfgang Maier, Jacques Mallet, Sara Marsal, Manuel Mattheisen, Morten Mattingsdal, Robert W. McCarley, Colm McDonald, Sandra Meier, Carin J. Meijer, Bela Melegh, Raquelle I. Mesholam-Gately, Andres Metspalu, Patricia T. Michie, Vihra Milanova, Younes Mokrab, Derek W. Morris, Kieran C. Murphy, Inez Myin-Germeys, Mari Nelis, Igor Nenadic, Deborah A. Nertney, Gerald Nestadt, Kristin K. Nicodemus, Liene Nikitina-Zake, Laura Nisenbaum, Annelie Nordin, Eadbhard O’Callaghan, Colm O’Dushlaine, F. Anthony O’Neill, Sang-Yun Oh, Ann Olincy, Line Olsen, Jim Van Os, Christos Pantelis, George N. Papadimitriou, Sergi Papiol, Elena Parkhomenko, Tiina Paunio, Milica Pejovic-Milovancevic, Diana O. Perkins, Olli Pietiläinen, Jonathan Pimm, Andrew J. Pocklington, John Powell, Alkes Price, Ann E. Pulver, Shaun M. Purcell, Digby Quested, Henrik B. Rasmussen, Abraham Reichenberg, Mark A. Reimers, Alexander L. Richards, Joshua L. Roffman, Panos Roussos, Douglas M. Ruderfer, Veikko Salomaa, Ulrich Schall, Christian R. Schubert, Sibylle G. Schwab, Edward M. Scolnick, Rodney J. Scott, Larry J. Seidman, Engilbert Sigurdsson, Teimuraz Silagadze, Jeremy M. Silverman, Kang Sim, Petr Slominsky, Hon-Cheong So, Chris C.A. Spencer, Hreinn Stefansson, Stacy Steinberg, Elisabeth Stogmann, Richard E. Straub, Eric Strengman, Jana Strohmaier, T. Scott Stroup, Mythily Subramaniam, Jaana Suvisaari, Dragan M. Svrakic, Jin P. Szatkiewicz, Erik Söderman, Srinivas Thirumalai, Draga Toncheva, Sarah Tosato, Juha Veijola, John Waddington, Dermot Walsh, Dai Wang, Qiang Wang, Bradley T. Webb, Mark Weiser, Dieter B. Wildenauer, Nigel M. Williams, Stephanie Williams, Stephanie H. Witt, Aaron R. Wolen, Emily H.M. Wong, Brandon K. Wormley, Hualin Simon Xi, Clement C. Zai, Xuebin Zheng, Fritz Zimprich, Naomi R. Wray, Kari Stefansson, Peter M. Visscher, Douglas H.R. Blackwood, Ariel Darvasi, Enrico Domenici, Michael Gill, Hugh Gurling, Christina M. Hultman, Assen V. Jablensky, Kenneth S. Kendler, Jo Knight, Qingqin S. Li, Jianjun Liu, Steven A. McCarroll, Jennifer L. Moran, Michael J. Owen, Carlos N. Pato, Danielle Posthuma, Pamela Sklar, Jens R. Wendland, Mark J. Daly, Michael C. O’Donovan, Peter Donnelly, Ines Barroso, Jenefer M. Blackwell, Matthew A. Brown, Juan P. Casas, Panos Deloukas, Audrey Duncanson, Janusz Jankowski, Hugh S. Markus, Christopher G. Mathew, Colin N.A. Palmer, Robert Plomin, Anna Rautanen, Stephen J. Sawcer, Richard C. Trembath, Ananth C. Viswanathan, Nicholas W. Wood, Gavin Band, Céline Bellenguez, Colin Freeman, Eleni Giannoulatou, Garrett Hellenthal, Richard Pearson, Matti Pirinen, Amy Strange, Zhan Su, Damjan Vukcevic, Cordelia Langford, Hannah Blackburn, Suzannah J. Bumpstead, Serge Dronov, Sarah Edkins, Matthew Gillman, Emma Gray, Rhian Gwilliam, Naomi Hammond, Sarah E. Hunt, Alagurevathi Jayakumar, Jennifer Liddle, Owen T. McCann, Simon C. Potter, Radhi Ravindrarajah, Michelle Ricketts, Avazeh Tashakkori-Ghanbaria, Matthew Waller, Paul Weston, Pamela Whittaker, Sara Widaa, Mark I. McCarthy, Maria J. Arranz, Steven Bakker, Stephan Bender, Benedicto Crespo-Facorro, Jeremy Hall, Conrad Iyegbe, Stephen Lawrie, Kuang Lin, Don H. Linszen, Ignacio Mata, Muriel Walshe, Matthias Weisbrod, Durk Wiersma, Vassily Trubetskoy, Yunpeng Wang, Jonathan R.I. Coleman, Héléna A. Gaspar, Christiaan A. de Leeuw, Jennifer M. Whitehead Pavlides, Maciej Trzaskowski, Enda M. Byrne, Liam Abbott, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Adebayo Anjorin, Verneri Antilla, Swapnil Awasthi, Judith A. Badner, Marie Bækvad-Hansen, Jack D. Barchas, Nicholas Bass, Michael Bauer, Richard Belliveau, Carsten Bøcker Pedersen, Erlend Bøen, Marco P. Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Jonas Bybjerg-Grauholm, Miquel Casas, Felecia Cerrato, Kimberly Chambert, Alexander W. Charney, Danfeng Chen, Claire Churchhouse, Toni-Kim Clarke, William Coryell, David W. Craig, Cristiana Cruceanu, Piotr M. Czerski, Anders M. Dale, Simone de Jong, Jurgen Del-Favero, J. Raymond DePaulo, Amanda L. Dobbyn, Ashley Dumont, Torbjørn Elvsåshagen, Chun Chieh Fan, Sascha B. Fischer, Matthew Flickinger, Tatiana M. Foroud, Liz Forty, Christine Fraser, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Marianne Giørtz Pedersen, Jaqueline Goldstein, Scott D. Gordon, Katherine Gordon-Smith, Elaine K. Green, Melissa J. Green, Tiffany A. Greenwood, Weihua Guan, Martin Hautzinger, Urs Heilbronner, Maria Hipolito, Dominic Holland, Laura Huckins, Jessica S. Johnson, Radhika Kandaswamy, Robert Karlsson, Sarah Kittel-Schneider, Anna C. Koller, Ralph Kupka, Catharina Lavebratt, Jacob Lawrence, William B. Lawson, Markus Leber, Phil H. Lee, Shawn E. Levy, Jun Z. Li, Chunyu Liu, Anna Maaser, Donald J. MacIntyre, Pamela B. Mahon, Lina Martinsson, Steve McCarroll, Peter McGuffin, Melvin G. McInnis, James D. McKay, Helena Medeiros, Sarah E. Medland, Fan Meng, Grant W. Montgomery, Thomas W. Mühleisen, Hoang Nguyen, Caroline M. Nievergelt, Annelie Nordin Adolfsson, Evaristus A. Nwulia, Claire O'Donovan, Loes M. Olde Loohuis, Anil P.S. Ori, Lilijana Oruc, Urban Ösby, Amy Perry, Andrea Pfennig, Eline J. Regeer, Céline S. Reinbold, John P. Rice, Fabio Rivas, Margarita Rivera, Euijung Ryu, Cristina Sánchez-Mora, Alan F. Schatzberg, William A. Scheftner, Nicholas J. Schork, Cynthia Shannon Weickert, Tatyana Shehktman, Paul D. Shilling, Claire Slaney, Janet L. Sobell, Christine Søholm Hansen, Anne T. Spijker, Michael Steffens, John S. Strauss, Szabolcs Szelinger, Robert C. Thompson, Thorgeir E. Thorgeirsson, Jens Treutlein, Helmut Vedder, Weiqing Wang, Stanley J. Watson, Thomas W. Weickert, Simon Xi, Wei Xu, Allan H. Young, Peter Zandi, Peng Zhang, Sebastian Zöllner, Abdel Abdellaoui, Tracy M. Air, Till F.M. Andlauer, Silviu-Alin Bacanu, Aartjan T.F. Beekman, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Lucía Colodro-Conde, Baptiste Couvy-Duchesne, Gregory E. Crawford, Gail Davies, Ian J. Deary, Eske M. Derks, Nese Direk, Conor V. Dolan, Erin C. Dunn, Thalia C. Eley, Farnush Farhadi Hassan Kiadeh, Hilary K. Finucane, Jerome C. Foo, Fernando S. Goes, Lynsey S. Hall, Thomas F. Hansen, Ian B. Hickie, Georg Homuth, Carsten Horn, David M. Howard, Marcus Ising, Rick Jansen, Ian Jones, Lisa A. Jones, Eric Jorgenson, Isaac S. Kohane, Julia Kraft, Warren W. Kretzschmar, Zoltán Kutalik, Yihan Li, Penelope A. Lind, Dean F. MacKinnon, Robert M. Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Christel M. Middeldorp, Evelin Mihailov, Francis M. Mondimore, Sara Mostafavi, Matthias Nauck, Bernard Ng, Michel G. Nivard, Dale R. Nyholt, Paul F. O'Reilly, Hogni Oskarsson, Jodie N. Painter, Roseann E. Peterson, Wouter J. Peyrot, Giorgio Pistis, Jorge A. Quiroz, Per Qvist, Saira Saeed Mirza, Robert Schoevers, Eva C. Schulte, Ling Shen, Stanley I. Shyn, Grant C.B. Sinnamon, Johannes H. Smit, Daniel J. Smith, Katherine E. Tansey, Henning Teismann, Wesley Thompson, Pippa A. Thomson, Matthew Traylor, André G. Uitterlinden, Daniel Umbricht, Albert M. van Hemert, Shantel Marie Weinsheimer, Jürgen Wellmann, Yang Wu, Hualin S. Xi, Jian Yang, Futao Zhang, Volker Arolt, Klaus Berger, Udo Dannlowski, Katharina Domschke, Caroline Hayward, Andrew C. Heath, Stefan Kloiber, Glyn Lewis, Pamela AF. Madden, Patrik K. Magnusson, Preben Bo Mortensen, Michael C. O'Donovan, Sara A. Paciga, Nancy L. Pedersen, David J. Porteous, Catherine Schaefer, Henry Völzke, Marco Bortolato, Janita Bralten, Cynthia M. Bulik, Christie L. Burton, Caitlin E. Carey, Lea K. Davis, Laramie E. Duncan, Howard J. Edenberg, Lauren Erdman, Stephen V. Faraone, Slavina B. Goleva, Wei Guo, Christopher Hübel, Laura M. Huckins, Ekaterina A. Khramtsova, Joanna Martin, Carol A. Mathews, Elise Robinson, Eli Stahl, Barbara E. Stranger, Michela Traglia, Raymond K. Walters, Lauren A. Weiss, Stacey J. Winham, Yin Yao, Kristjar Skajaa, Markus Nöthen, Michael Owen, Robert H. Yolken, Niels Plath, Jonathan Mill, Daniel Geschwind
Publikováno v:
Biological Psychiatry, 91(1), 102-117. Elsevier Science
Biological Psychiatry, 91(1), 102-117. Elsevier USA
Blokland, G A M, Grove, J, Chen, C Y, Cotsapas, C, Tobet, S, Handa, R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH 2022, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry, vol. 91, no. 1, pp. 102-117 . https://doi.org/10.1016/j.biopsych.2021.02.972
Biological Psychiatry, 91, 1, pp. 102-117
Biological Psychiatry
Biological Psychiatry, 91, 102-117
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH 2021, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2021.02.972
Biol Psychiatry
Biological psychiatry 91(1), 102-117 (2022). doi:10.1016/j.biopsych.2021.02.972
Biological Psychiatry. Elsevier USA
Biological Psychiatry, 91(1), 102-117. Elsevier Inc.
Biological psychiatry. Elsevier USA
Blokland, G A M, Grove, J, Chen, C, Cotsapas, C, Tobet, S, Sullivan, P F, Boomsma, D I, Penninx, B W J H, Hottenga, J-J, de Geus, E J C, Willemsen, G, Milaneschi, Y, Als, T D, Børglum, A D, Petryshen, T L, Smoller, J W, Goldstein, J M, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH 2022, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry, vol. 91, no. 1, pp. 102-117 . https://doi.org/10.1016/j.biopsych.2021.02.972
Biological Psychiatry, 91(1), 102-117. Elsevier USA
Blokland, G A M, Grove, J, Chen, C Y, Cotsapas, C, Tobet, S, Handa, R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH 2022, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry, vol. 91, no. 1, pp. 102-117 . https://doi.org/10.1016/j.biopsych.2021.02.972
Biological Psychiatry, 91, 1, pp. 102-117
Biological Psychiatry
Biological Psychiatry, 91, 102-117
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH 2021, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2021.02.972
Biol Psychiatry
Biological psychiatry 91(1), 102-117 (2022). doi:10.1016/j.biopsych.2021.02.972
Biological Psychiatry. Elsevier USA
Biological Psychiatry, 91(1), 102-117. Elsevier Inc.
Biological psychiatry. Elsevier USA
Blokland, G A M, Grove, J, Chen, C, Cotsapas, C, Tobet, S, Sullivan, P F, Boomsma, D I, Penninx, B W J H, Hottenga, J-J, de Geus, E J C, Willemsen, G, Milaneschi, Y, Als, T D, Børglum, A D, Petryshen, T L, Smoller, J W, Goldstein, J M, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH 2022, ' Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders ', Biological Psychiatry, vol. 91, no. 1, pp. 102-117 . https://doi.org/10.1016/j.biopsych.2021.02.972
Contains fulltext : 248656.pdf (Publisher’s version ) (Closed access) BACKGROUND: Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f533f1ee51f80e7e36bf1609dfb7ae
https://cris.maastrichtuniversity.nl/en/publications/9ef4e1d0-ea1a-49c3-b815-9c883eae4707
https://cris.maastrichtuniversity.nl/en/publications/9ef4e1d0-ea1a-49c3-b815-9c883eae4707
Autor:
Hilda Solanoy, Morgan Sheng, Gui-Qiu Yu, Jesse E. Hanson, Gauri Deshmukh, Benjamin D. Sellers, Tzu-Ming Wang, Yelin Chen, Justin Elstrott, Connie Chan, Zhiyu Jiang, Thomas A. Kim, David H. Hackos, Jacob Schwarz, Jorge J. Palop, T. Michael Gill, Matthew Volgraf, Keran Ma, Jeffrey Simms, Kimberly Scearce-Levie, Martin Weber, Bianca M. Liederer, Sandrine Saillet, Abdullah S. Khan, Robby M. Weimer, Benjamin Liu
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 381-396.e4 (2020)
Elsevier
Cell reports, vol 30, iss 2
Cell reports
Elsevier
Cell reports, vol 30, iss 2
Cell reports
SUMMARY NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR
Autor:
Evangelia K. Papachristou, Michael Gill, Martin L. Miller, Danish Memon, Pedro Beltrao, Clive D'Santos, David Ochoa
Publikováno v:
Cell Reports, 35 (7)
Cell Reports, Vol 35, Iss 7, Pp 109155-(2021)
Cell Reports
Cell Reports, Vol 35, Iss 7, Pp 109155-(2021)
Cell Reports
Summary Somatic DNA copy number variations (CNVs) are prevalent in cancer and can drive cancer progression, albeit with often uncharacterized roles in altering cell signaling states. Here, we integrate genomic and proteomic data for 5,598 tumor sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6320e5673accbc260087d519fabec3c5
Autor:
Jonathan R.I. Coleman, Héléna A. Gaspar, Julien Bryois, Gerome Breen, Enda M. Byrne, Andreas J. Forstner, Peter A. Holmans, Christiaan A. de Leeuw, Manuel Mattheisen, Andrew McQuillin, Jennifer M. Whitehead Pavlides, Tune H. Pers, Stephan Ripke, Eli A. Stahl, Stacy Steinberg, Vassily Trubetskoy, Maciej Trzaskowski, Yunpeng Wang, Liam Abbott, Abdel Abdellaoui, Mark J. Adams, Annelie Nordin Adolfsson, Esben Agerbo, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Thomas D. Als, Till F.M. Andlauer, Adebayo Anjorin, Verneri Antilla, Sandra Van der Auwera, Swapnil Awasthi, Silviu-Alin Bacanu, Judith A. Badner, Marie Bækvad-Hansen, Jack D. Barchas, Nicholas Bass, Michael Bauer, Aartjan T.F. Beekman, Richard Belliveau, Sarah E. Bergen, Tim B. Bigdeli, Elisabeth B. Binder, Erlend Bøen, Marco Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, William Byerley, Na Cai, Miquel Casas, Enrique Castelao, Felecia Cerrato, Pablo Cervantes, Kimberly Chambert, Alexander W. Charney, Danfeng Chen, Jane Hvarregaard Christensen, Claire Churchhouse, David St Clair, Toni-Kim Clarke, Lucía Colodro-Conde, William Coryell, Baptiste Couvy-Duchesne, David W. Craig, Gregory E. Crawford, Cristiana Cruceanu, Piotr M. Czerski, Anders M. Dale, Gail Davies, Ian J. Deary, Franziska Degenhardt, Jurgen Del-Favero, J Raymond DePaulo, Eske M. Derks, Nese Direk, Srdjan Djurovic, Amanda L. Dobbyn, Conor V. Dolan, Ashley Dumont, Erin C. Dunn, Thalia C. Eley, Torbjørn Elvsåshagen, Valentina Escott-Price, Chun Chieh Fan, Hilary K. Finucane, Sascha B. Fischer, Matthew Flickinger, Jerome C. Foo, Tatiana M. Foroud, Liz Forty, Josef Frank, Christine Fraser, Nelson B. Freimer, Louise Frisén, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Fernando S. Goes, Jaqueline Goldstein, Scott D. Gordon, Katherine Gordon-Smith, Elaine K. Green, Melissa J. Green, Tiffany A. Greenwood, Jakob Grove, Weihua Guan, Lynsey S. Hall, Marian L. Hamshere, Christine Søholm Hansen, Thomas F. Hansen, Martin Hautzinger, Urs Heilbronner, Albert M. van Hemert, Stefan Herms, Ian B. Hickie, Maria Hipolito, Per Hoffmann, Dominic Holland, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, Laura Huckins, Marcus Ising, Stéphane Jamain, Rick Jansen, Jessica S. Johnson, Simone de Jong, Eric Jorgenson, Anders Juréus, Radhika Kandaswamy, Robert Karlsson, James L. Kennedy, Farnush Farhadi Hassan Kiadeh, Sarah Kittel-Schneider, James A. Knowles, Manolis Kogevinas, Isaac S. Kohane, Anna C. Koller, Julia Kraft, Warren W. Kretzschmar, Jesper Krogh, Ralph Kupka, Zoltán Kutalik, Catharina Lavebratt, Jacob Lawrence, William B. Lawson, Markus Leber, Phil H. Lee, Shawn E. Levy, Jun Z. Li, Yihan Li, Penelope A. Lind, Chunyu Liu, Loes M. Olde Loohuis, Anna Maaser, Donald J. MacIntyre, Dean F. MacKinnon, Pamela B. Mahon, Wolfgang Maier, Robert M. Maier, Jonathan Marchini, Lina Martinsson, Hamdi Mbarek, Steve McCarroll, Patrick McGrath, Peter McGuffin, Melvin G. McInnis, James D. McKay, Helena Medeiros, Sarah E. Medland, Divya Mehta, Fan Meng, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Saira Saeed Mirza, Francis M. Mondimore, Grant W. Montgomery, Derek W. Morris, Sara Mostafavi, Thomas W. Mühleisen, Niamh Mullins, Matthias Nauck, Bernard Ng, Hoang Nguyen, Caroline M. Nievergelt, Michel G. Nivard, Evaristus A. Nwulia, Dale R. Nyholt, Claire O'Donovan, Paul F. O'Reilly, Anil P.S. Ori, Lilijana Oruc, Urban Ösby, Hogni Oskarsson, Jodie N. Painter, José Guzman Parra, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Amy Perry, Roseann E. Peterson, Erik Pettersson, Wouter J. Peyrot, Andrea Pfennig, Giorgio Pistis, Shaun M. Purcell, Jorge A. Quiroz, Per Qvist, Eline J. Regeer, Andreas Reif, Céline S. Reinbold, John P. Rice, Brien P. Riley, Fabio Rivas, Margarita Rivera, Panos Roussos, Douglas M. Ruderfer, Euijung Ryu, Cristina Sánchez-Mora, Alan F. Schatzberg, William A. Scheftner, Robert Schoevers, Nicholas J. Schork, Eva C. Schulte, Tatyana Shehktman, Ling Shen, Jianxin Shi, Paul D. Shilling, Stanley I. Shyn, Engilbert Sigurdsson, Claire Slaney, Olav B. Smeland, Johannes H. Smit, Daniel J. Smith, Janet L. Sobell, Anne T. Spijker, Michael Steffens, John S. Strauss, Fabian Streit, Jana Strohmaier, Szabolcs Szelinger, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Robert C. Thompson, Wesley Thompson, Pippa A. Thomson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, André G. Uitterlinden, Daniel Umbricht, Helmut Vedder, Alexander Viktorin, Peter M. Visscher, Weiqing Wang, Stanley J. Watson, Bradley T. Webb, Cynthia Shannon Weickert, Thomas W. Weickert, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Wei Xu, Jian Yang, Allan H. Young, Peter Zandi, Peng Zhang, Futao Zhang, Sebastian Zollner, Rolf Adolfsson, Ingrid Agartz, Martin Alda, Volker Arolt, Lena Backlund, Bernhard T. Baune, Frank Bellivier, Klaus Berger, Wade H. Berrettini, Joanna M. Biernacka, Douglas H.R. Blackwood, Michael Boehnke, Dorret I. Boomsma, Aiden Corvin, Nicholas Craddock, Mark J. Daly, Udo Dannlowski, Enrico Domenici, Katharina Domschke, Tõnu Esko, Bruno Etain, Mark Frye, Janice M. Fullerton, Elliot S. Gershon, E.J.C. de Geus, Michael Gill, Fernando Goes, Hans J. Grabe, Maria Grigoroiu-Serbanescu, Steven P. Hamilton, Joanna Hauser, Caroline Hayward, Andrew C. Heath, David M. Hougaard, Christina M. Hultman, Ian Jones, Lisa A. Jones, René S. Kahn, Kenneth S. Kendler, George Kirov, Stefan Kloiber, Mikael Landén, Marion Leboyer, Glyn Lewis, Qingqin S. Li, Jolanta Lissowska, Susanne Lucae, Pamela A.F. Madden, Patrik K. Magnusson, Nicholas G. Martin, Fermin Mayoral, Susan L. McElroy, Andrew M. McIntosh, Francis J. McMahon, Ingrid Melle, Andres Metspalu, Philip B. Mitchell, Gunnar Morken, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Richard M. Myers, Benjamin M. Neale, Vishwajit Nimgaonkar, Merete Nordentoft, Markus M. Nöthen, Michael C. O'Donovan, Ketil J. Oedegaard, Michael J. Owen, Sara A. Paciga, Carlos Pato, Michele T. Pato, Nancy L. Pedersen, Brenda W.J. H. Penninx, Roy H. Perlis, David J. Porteous, Danielle Posthuma, James B. Potash, Martin Preisig, Josep Antoni Ramos-Quiroga, Marta Ribasés, Marcella Rietschel, Guy A. Rouleau, Catherine Schaefer, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Alessandro Serretti, Jordan W. Smoller, Hreinn Stefansson, Kari Stefansson, Eystein Stordal, Henning Tiemeier, Gustavo Turecki, Rudolf Uher, Arne E. Vaaler, Eduard Vieta, John B. Vincent, Henry Völzke, Myrna M. Weissman, Thomas Werge, Ole A. Andreassen, Anders D. Børglum, Sven Cichon, Howard J. Edenberg, Arianna Di Florio, John Kelsoe, Douglas F. Levinson, Cathryn M. Lewis, John I. Nurnberger, Roel A. Ophoff, Laura J. Scott, Pamela Sklar, Patrick F. Sullivan, Naomi R. Wray
Publikováno v:
Biological Psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Willemsen, G, Boomsma, D I, de Geus, E J C, W J H Penninx, B & Posthuma, D 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry
Biol Psychiatry
Coleman, J R I, Gaspar, H A, Bryois, J, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J H 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Psychiatric Genomics Consortium 2019, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry 88(2), P169-184, (2020). doi:10.1016/j.biopsych.2019.10.015
Biological Psychiatry, 88(2), 169-184. Elsevier Inc.
Biological psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Gaspar, H A, Bryois, J & Breen, G 2020, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological psychiatry .
Coleman, J R I, Gaspar, H A, Bryois, J, Byrne, E M, Forstner, A J, Holmans, P A, de Leeuw, C A, Mattheisen, M, McQuillin, A, Whitehead Pavlides, J M, Pers, T H, Ripke, S, Stahl, E A, Steinberg, S, Trubetskoy, V, Trzaskowski, M, Wang, Y, Abbott, L, Abdellaoui, A, Adams, M J, Adolfsson, A N, Agerbo, E, Akil, H, Albani, D, Alliey-Rodriguez, N, Als, T D, Andlauer, T F M, Anjorin, A, Antilla, V, Van der Auwera, S, Awasthi, S, Bacanu, S A, Badner, J A, Bækvad-Hansen, M, Barchas, J D, Bass, N, Bauer, M, Beekman, A T F, Belliveau, R, Bergen, S E, Bigdeli, T B, Binder, E B, Bøen, E, Hansen, C S, Hansen, T F, Krogh, J, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Print: 0006-3223
2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological Psychiatry
Coleman, J R I, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Derks, E M, Dolan, C V, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Peyrot, W J, Willemsen, G, Boomsma, D I, de Geus, E J C, W J H Penninx, B & Posthuma, D 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry
Biol Psychiatry
Coleman, J R I, Gaspar, H A, Bryois, J, Breen, G, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Christensen, J H 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Psychiatric Genomics Consortium 2019, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological psychiatry 88(2), P169-184, (2020). doi:10.1016/j.biopsych.2019.10.015
Biological Psychiatry, 88(2), 169-184. Elsevier Inc.
Biological psychiatry, 88(2), 169-184. Elsevier USA
Coleman, J R I, Gaspar, H A, Bryois, J & Breen, G 2020, ' The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls ', Biological psychiatry .
Coleman, J R I, Gaspar, H A, Bryois, J, Byrne, E M, Forstner, A J, Holmans, P A, de Leeuw, C A, Mattheisen, M, McQuillin, A, Whitehead Pavlides, J M, Pers, T H, Ripke, S, Stahl, E A, Steinberg, S, Trubetskoy, V, Trzaskowski, M, Wang, Y, Abbott, L, Abdellaoui, A, Adams, M J, Adolfsson, A N, Agerbo, E, Akil, H, Albani, D, Alliey-Rodriguez, N, Als, T D, Andlauer, T F M, Anjorin, A, Antilla, V, Van der Auwera, S, Awasthi, S, Bacanu, S A, Badner, J A, Bækvad-Hansen, M, Barchas, J D, Bass, N, Bauer, M, Beekman, A T F, Belliveau, R, Bergen, S E, Bigdeli, T B, Binder, E B, Bøen, E, Hansen, C S, Hansen, T F, Krogh, J, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological Psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Print: 0006-3223
2020, ' The Genetics of the Mood Disorder Spectrum : Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls ', Biological psychiatry, vol. 88, no. 2, pp. 169-184 . https://doi.org/10.1016/j.biopsych.2019.10.015
Biological Psychiatry
BackgroundMood disorders (including major depressive disorder and bipolar disorder) affect 10-20% of the population. They range from brief, mild episodes to severe, incapacitating conditions that markedly impact lives. Despite their diagnostic distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c3524cd941abdd57f08a40b8f33772
https://research.vu.nl/en/publications/27d723ef-6f1b-4afb-a2ff-338058b3e20b
https://research.vu.nl/en/publications/27d723ef-6f1b-4afb-a2ff-338058b3e20b
Autor:
Dan Rujescu, Vidar M. Steen, Eva Krapohl, Aarno Palotie, Elisabeth Widen, Ingrid Melle, Patrick Sullivan, Katrina L. Grasby, Stephan Ripke, Anke R. Hammerschlag, Christiaan de Leeuw, Panos Bitsios, Nikos C. Stefanis, Tonya White, Gail Davies, Ahmad R. Hariri, Philip R. Jansen, Peter B. Barr, John M. Starr, Max Lam, Ian J. Deary, Sara Hägg, Dimitrios Avramopoulos, Bettina Konte, Anil K. Malhotra, Delilah Zabaneh, Kjetil Sundet, Tinca J. C. Polderman, Ornit Chiba-Falek, Jakob Kaminski, Danielle M. Dick, Andrea Christoforou, Jin Yu, Gunter Schumann, Matthew A. Scult, Anna C. Need, Jens Hjerling-Leffler, Gonçalo R. Abecasis, Kenneth S. Kendler, Todd Lencz, Dwight Dickinson, Bradley T. Webb, Elizabeth T. Cirulli, Stephanie Le Hellard, Gerome Breen, Astri J. Lundervold, Hannah Young, Erin Burke Quinlan, William Ollier, Nikolaos Smyrnis, Emily Drabant Conley, Danielle Posthuma, Sten Linnarsson, Aristotle N. Voineskos, Edythe D. London, Pamela DeRosse, Russell A. Poldrack, Jonathan R. I. Coleman, Jeanne E. Savage, Sarah E. Medland, Ana B. Muñoz-Manchado, Richard E. Straub, Robert Plomin, Ida K. Karlsson, Nathan G. Skene, Dan E. Arking, Birgit Debrabant, Joey W. Trampush, Matthew C. Keller, Mats Nagel, Gary Donohoe, Chandra A. Reynolds, Panos Roussos, Lene Christiansen, Ivar Reinvang, Ole A. Andreassen, Antony Payton, Robert Karlsson, Margaret J. Wright, Deborah C. Koltai, Jari Lahti, Andreas Heinz, Tyrone D. Cannon, Eliza Congdon, Olav B. Smeland, Stella G. Giakoumaki, Marianne Nygaard, Julien Bryois, M. Arfan Ikram, Nancy L. Pedersen, Katri Räikkönen, Daniel R. Weinberger, Neil Pendleton, Swapnil Awasthi, Sven Stringer, Nelson A. Freimer, Aiden Corvin, Kyoko Watanabe, David C. Glahn, Henning Tiemeier, Grant W. Montgomery, Narelle K. Hansell, Robert M. Bilder, Katherine E. Burdick, Srdjan Djurovic, David C. Liewald, Sophie van der Sluis, Thomas Espeseth, Scott I. Vrieze, Fred W. Sabb, Nicholas G. Martin, Michael Gill, Emma Knowles, Derek W. Morris, Alex Hatzimanolis, Ina Giegling, Johan G. Eriksson
Publikováno v:
Nature Genetics, 50(7), 912-+. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Nature Genetics, 50(7), 912-919. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, 0, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Christiansen, L & Debrabant, B 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912–919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Nature Genetics, 50(7), 912-919. Nature Publishing Group
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, 0, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, van der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, DeRosse, P, Dickinson, D, Djurovic, S, Christiansen, L & Debrabant, B 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912–919 . https://doi.org/10.1038/s41588-018-0152-6
Savage, J E, Jansen, P R, Stringer, S, Watanabe, K, Bryois, J, De Leeuw, C A, Nagel, M, Awasthi, S, Barr, P B, Coleman, J R I, Grasby, K L, Hammerschlag, A R, Kaminski, J A, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, C A, Trampush, J W, Young, H, Zabaneh, D, Hägg, S, Hansell, N K, Karlsson, I K, Linnarsson, S, Montgomery, G W, Muñoz-Manchado, A B, Quinlan, E B, Schumann, G, Skene, N G, Webb, B T, White, T, Arking, D E, Avramopoulos, D, Bilder, R M, Bitsios, P, Burdick, K E, Cannon, T D, Chiba-Falek, O, Christoforou, A, Cirulli, E T, Congdon, E, Corvin, A, Davies, G, Deary, I J, Derosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, E D, Eriksson, J G, Espeseth, T, Freimer, N A, Giakoumaki, S, Giegling, I, Gill, M, Glahn, D C, Hariri, A R, Hatzimanolis, A, Keller, M C, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, D C, London, E, Lundervold, A J, Malhotra, A K, Melle, I, Morris, D, Need, A C, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, R A, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, F W, Scult, M A, Smeland, O B, Smyrnis, N, Starr, J M, Steen, V M, Stefanis, N C, Straub, R E, Sundet, K, Tiemeier, H, Voineskos, A N, Weinberger, D R, Widen, E, Yu, J, Abecasis, G, Andreassen, O A, Breen, G, Christiansen, L, Debrabant, B, Dick, D M, Heinz, A, Hjerling-Leffler, J, Ikram, M A, Kendler, K S, Martin, N G, Medland, S E, Pedersen, N L, Plomin, R, Polderman, T J C, Ripke, S, Van Der Sluis, S, Sullivan, P F, Vrieze, S I, Wright, M J & Posthuma, D 2018, ' Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence ', Nature Genetics, vol. 50, no. 7, pp. 912-919 . https://doi.org/10.1038/s41588-018-0152-6
Intelligence is highly heritable 1 and a major determinant of human health and well-being 2 . Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in intelligence 3-7 , but much about its genetic underpinnings remains
Autor:
Aneel Bhangu, Dmitri Nepogodiev, Natalie Ives, Laura Magill, James Glasbey, Colm Forde, Thue Bisgaard, Kelly Handley, Samir Mehta, Dion Morton, Thomas Pinkney, James Brown, Kaori Futaba, Sarah Khan, Arvind Pallan, Abhilasha Patel, Steve Ashdown-Phillips, Tracy Roberts, Susan Jowett, Lorraine Munetsi, Andrew Torrance, Nicholas Hilken, Matt Hill, Mark Hunter, Susan Leek, Helen Lilly, Amruta Sawant, Alexandra Vince, Michael Walters, Willem Bemelman, Marjolein Blussé, Wernard Borstlap, Olivier RC Busch, Christianne Buskens, Charlotte Klaver, Hendrik Marsman, Oddeke van Ruler, Pieter Tanis, Emma Westerduin, Dennis Wicherts, Parthasarathi Das, Sharadah Essapen, Victoria Frost, Ana Glennon, Catherine Gray, Anwar Hussain, Lisa McNichol, Pasha Nisar, Humphrey Scott, Jonathan Trickett, Prateesh Trivedi, Daniel White, Talakalukoppa Amarnath, Rohan Ardley, Robin Gupta, Emily Hall, Kathryn Hodgkins, Harjeet Narula, Terri-Ann Sewell, John M Simms, Julie Toms, Tim White, Angela Atkinson, Dan Beral, Nicola Lancaster, Felicity Mackenzie, Tim Wilson, David Cruttenden-Wood, Jackie Gibbins, Mark Halls, Dennise Hill, Karen Hogben, Stephanie Jones, Michael J Lamparelli, Mark Lewis, Sarah Moreton, Paul Ng, Arabis Oglesby, James Orbell, Benjamin Stubbs, Krishnan Subramanian, Anjay Talwar, Simon Wilsher, Mohammed Al-Rashedy, Catherine Fensom, Muhammed Gok, Lisa Hardstaff, Kamran Malik, Mohammed Sadat, Barbara Townley, Lesley Wilkinson, Tracey Cosier, Sudhakar Mangam, Mohamed Rabie, Graham Broadley, John Canny, Simon Fallis, Nikki Green, Ahmed Hawash, Sharad Karandikar, Mehboob Mirza, Edward Rawstorne, Julie Reddan, Jonathan Richardson, Chris Thompson, Kathryn Waite, Haney Youssef, Lindsey De Nes, Steffen Rosenstock, Pernille Strandfelt, Mikkel Westen, Kamal Aryal, Kirosh Shankar Kshatriya, Roshan Lal, Vamsi Velchuru, Elva Wilhelmsen, Ayesha Akbar, Anthony Antoniou, Sue Clark, Pooja Datt, Jason Goh, Ian Jenkins, Robin Kennedy, Yasuko Maeda, Piero Nastro, Harriet Owen, Robin KS Phillips, Janindra Warusavitarne, Joanne Bradley-Potts, Peter Charleston, Hamish Clouston, Sarah Duff, Taher Fatayer, Anna Gipson, Nick Heywood, Muneer Junejo, James Kennedy, Helen Lalor, Chris Manning, Richard McCormick, Kathryn Parmar, Stephen Preston, Aswatha Ramesh, Abhiram Sharma, Karen Telford, Abidemi Adeosun, Toby Hammond, Susan Smolen, Joanne Topliffe, James G Docherty, Michael Lim, Kathleen Macleod, Eimar Monaghan, Lesley Patience, Ian Thomas, Kenneth G Walker, Michael Walker, Angus JM Watson, Amanda Burgess, Yasser Ghanem, Georgina Glister, Sandeep Kapur, Abhilash Paily, Atanu Pal, Rathinam Ravikumar, Melissa Rosbergen, Kevin Sargen, Christopher Speakman, Anil K Agarwal, Amlan Banerjee, David Borowski, Dharmendra Garg, Talvinder Gill, Tracey Johnston, Susan Kelsey, Phanibhushana Chakravarthy Munipalle, Mohamed Tabaqchali, Deborah Wilson, Austin Acheson, Heather Cripps, Ahmed El-Sharkawy, Oliver Ng, Parveen Sharma, Kym Ward, Dawne Chandler, Edward Courtney, John Bunni, Katrina Butcher, Stephen Dalton, Ian Flindall, Joyce Katebe, Pratik Roy, Jeremy Tate, Tracy Vincent, Michael ER Williamson, James Wood, Mark Bignell, Graham Branagan, Jack Broardhurst, Helen Chave, Hilary Dean, Nigel D'Souza, Gemma Foster, Simon Sleight, Rupesh Sutaria, Ishmail Ahmed, Misra Rai Budhoo, Julie Colley, Neil Cruickshank, Kathryn Gill, Anne Hayes, Howard Joy, Carrington Kamabjha, James Plowright, Simon Radley, Mr Rea, Vijay Thumbe, Philip Varghese, Richard Wilkin, Elzbieta Zulueta, Lynne Allsop, Bence Atkari, Krishnamurthy Badrinath, Prita Daliya, Mukul Dube, Cheryl Heeley, Richard Hind, Dominic Nash, Andrea Palfreman, Oliver Peacock, Nicholas Watson, Michelle Blodwell, Ali Javaid, Ashiq Mohamad, Karim Muhammad, Nafees Qureshi, Stephanie Ridgway, Kamran Siddiqui, Mamoon Solkar, Joanne Vere, Alexander Wordie, Jessica Chang, Sanaa Elgaddal, Marie Green, Marianne Hollyman, Nazzia Mirza, Jayne Rankin, Graham Williams, Wadah Ali, Anne Hardwick, Zakir Mohamed, Ahmad Navid, Kimberley Netherton, Mugurel Obreja, Milind Rao, Joanna Stringer, Athula Tennakoon, Timothy Bullen, Mansoor Butt, Robin Dawson, Sarah Dawson, Martin Farmer, Veerabhadram Garimella, Zoe Gates, Lisa Wilkings, Neil Yeomans, Olufunso Adedeji, Rashid Alalawi, Aamed Al Araimi, Shazad Ashraf, Simon Bach, Andrew Beggs, Carmen Cagigas, Mit Dattani, Nikolletta Dimitriou, Manijeh Ghods-Ghorbani, David Gourevitch, Geoffrey Haydon, Tariq Ismail, Christopher Keh, Dion G Morton, Mandip Narewal, Trifonas Papettas, Tom Pinkney, Aaron Poh, Edward Ranstorne, Timothy J Royle, Tahir Shah, Jagdeep Singh, Chris Smart, Nigel Suggett, Muhammad Tayyab, Deepak Vijayan, Ravinder Vohra, Naseem Wairaich, Denise Yeung, Richard Bamford, Joanne Chambers, David Cotton, Rebecca Houlihan, James Kynaston, Rob Longman, Amelia Lowe, David Messenger, Anwar Owais, Catherine Phillpott, Jamshed Shabbir, Phil Baragwanath, Charlotte El-Sayed, Anne Gaunt, Chetan Khatri, Peter McCullough, Stephen Ward, Ross Obukofe, Robert Stroud, David Mason, Nigel Williams, Ling S Wong, Sanjay Chaudhri, Jill Cooke, Melissa Cunha, Howard Fairey, Michael Norwood, Baljit Singh, Sarah Thomasset, Sian Abbott, Sarah Addison, James Archer, Robert Church, Erika Holford, Fionnaula Lenehan, Steve Odogwu, Lisa Richardson, Jane Sidebotham, Elaine Swan, Alison Tilley, Lynda Wagstaff, Isobel Amey, Yolanda Baird, Neil Cripps, Susanna Greenslade, Guy Harris, Bruce Levy, Paul Mckenzie, Alison Misselbrook, Sally Moore, Angela Skull, Deborah Nicol, Bala Reddy, Jessica Thrush, Miriam Iglesias Vecchio, Yvonne Dunn, Claire Williams, Sanjay Furtado, Michael Gill, Lydia Gilmore, Paul Goldsmith, Cezary Kocialkowski, Sadasivam Loganathan, Rabindra Nath, Marius Paraoan, Tracey Taylor, Andrew Allison, Joanna Allison, Nathan Curtis, Richard Dalton, Conrad D'Costa, Godwin Dennison, Jake Foster, Nader Francis, James Gibbons, Mohammed Hamdan, Alison Lewis, Jonathan Ockrim, Rishabha Sharma, Katie Spurdle, Saseendran Varadharajan, Assad Aghahoseini, David J Alexander, Dibyendu Bandyopadhyay, Ian Bradford, Praminthra Chitsabesan, Zoe Coleman, Andrew Gibson, Kostas Lasithiotakis, Dimitrios Panagiotou, Konstantinos Polyzois, Stevan Stojkovic, Nicholas Woodcock, Monica Wright, Rachel Hargest, Richard Jackson, Arumugam Rajesh, Olagunju Ogunbiyi, Andrew Slater, Ly-Mee Yu
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Lancet (London, England)
Lancet, 395(10222), 417-426. Elsevier Limited
Lancet, 395(10222), 417-426. Elsevier Limited
Summary Background Closure of an abdominal stoma, a common elective operation, is associated with frequent complications; one of the commonest and impactful is incisional hernia formation. We aimed to investigate whether biological mesh (collagen tis
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Jens Treutlein, James B. Potash, Cheynna A. Crowley, Paul F. O'Reilly, Francis M. Mondimore, Nicholas G. Martin, Jodie N. Painter, Qingqin S. Li, Tõnu Esko, Michael Conlon O'Donovan, Markus M. Nöthen, Toni-Kim Clarke, Roseann E. Peterson, Shantel Weinsheimer, Naomi R. Wray, Marie Bækvad-Hansen, Pamela F.A. Madden, Johannes H. Smit, Gonneke Willemsen, Thomas Hansen, Andrew C. Heath, Carsten Horn, Udo Dannlowski, Fulai Jin, Robert A. Schoevers, Jian Yang, Nicholas Eriksson, Marianne Giørtz Pedersen, Patrik K. E. Magnusson, Hans J. Grabe, Michael Gill, Lili Milani, Caroline Hayward, Shaun Purcell, Stanley I. Shyn, Penelope A. Lind, Giorgio Pistis, Michel G. Nivard, Thorgeir E. Thorgeirsson, Abdel Abdellaoui, Andres Metspalu, David J. Porteous, Anders D. Børglum, Christine Søholm Hansen, Scott D. Gordon, Nicholas John Craddock, Susanne Lucae, Douglas Blackwood, Jürgen Wellmann, Till M.F. Andlauer, Wesley K. Thompson, Chao Tian, Rudolf Uher, Nese Direk, Yuri Milaneschi, Paola Giusti-Rodríguez, Rick Jansen, Marcus Ising, Yang Wu, Jesper Krogh, Merete Nordentoft, Jouke-Jan Hottenga, Robert Maier, Ming Hu, Kari Stefansson, Glyn Lewis, Peter McGuffin, Wolfgang Maier, Erin C. Dunn, Bradley T. Webb, Gerome Breen, Henning Teismann, Eric Jorgenson, Jorge A. Quiroz, Brenda W.J.H. Penninx, Jonas Bybjerg-Grauholm, Warren W. Kretzschmar, Dean F. MacKinnon, Craig A. Stockmeier, Wouter J. Peyrot, Enrico Domenici, E. C.J. De Geus, Alexander Teumer, Henry Völzke, Yihan Li, Michael John Owen, Manuel Mattheisen, Bernard Ng, Baptiste Couvy-Duchesne, Daniel J. Smith, Jana Strohmaier, Vassily Trubetskoy, Volker Arolt, Douglas F. Levinson, Futao Zhang, Daniel Umbricht, Aartjan F.T. Beekman, David A. Hinds, Bernhard T. Baune, Henning Tiemeier, Hualin S. Xi, Hamdi Mbarek, Steven P. Hamilton, Stefan Kloiber, Fernando S. Goes, Jianxin Shi, Marcella Rietschel, Dale R. Nyholt, Zoltán Kutalik, Niamh Mullins, Grant W. Montgomery, Henriette N. Buttenschøn, Georg Homuth, Katharina Domschke, Alexander Viktorin, Hilary K. Finucane, Ashley R. Winslow, Saira Saeed Mirza, Fabian Streit, Erik Pettersson, Martin Preisig, Danielle Posthuma, Stephan Ripke, Lucía Colodro-Conde, Thalia C. Eley, Pippa A. Thomson, Thomas Werge, Enrique Castelao, Klaus Berger, Yun Li, Stacy Steinberg, Dorret I. Boomsma, Matthias Nauck, Sara Mostafavi, Jacqueline M. Lane, Katherine E. Tansey, Divya Mehta, Gregory E. Crawford, Andreas J. Forstner, Jane H. Christensen, Silviu Alin Bacanu, Julia Kraft, David M. Hougaard, Peter M. Visscher, Valentina Escott-Price, Donald J. MacIntyre, Sarah E. Medland, Per Qvist, Kenneth S. Kendler, Jordan W. Smoller, J. Raymond DePaulo, Ian J. Deary, Thomas G. Schulze, Julien Bryois, Ian B. Hickie, Helena Gaspar, Jonathan Mill, James A. Knowles, Cathryn M. Lewis, Hassan S. Dashti, Stefan Herms, Margarita Rivera, John P. Rice, Lynsey S. Hall, Eilis Hannon, Nancy L. Pedersen, Eva C. Schulte, Hreinn Stefansson, Maciej Trzaskowski, André G. Uitterlinden, Bertram Müller-Myhsok, Gail Davies, Mark Adams, Jakob Grove, Eske M. Derks, Sven Cichon, Jonathan I.R. Coleman, Sandra Van der Auwera, Myrna M. Weissman, Preben Bo Mortensen, Josef Frank, Enda M. Byrne, Esben Agerbo, Engilbert Sigurdsson, Xiaoxiao Liu, Patrick F. Sullivan, Carsten Bøcker Pedersen, Ole Mors, Catherine Schaefer, Richa Saxena, Albert M. van Hemert, Jonathan Marchini, Hogni Oskarsson, Franziska Degenhardt, Tracy Air, Elisabeth B. Binder, Christel M. Middeldorp, Farnush Hassan Farhadi Kiadeh, Conor V. Dolan, Sara A. Paciga, Per Hoffmann, Leina Lu, Andrew M. McIntosh, Tim B. Bigdeli, Stephanie H. Witt, Matthew Traylor, Grant Sinnamon, Brien P. Riley, Roy H. Perlis, Patrick J. McGrath, Craig L. Hyde, Ling Shen, Na Cai, Yunpeng Wang, Evelin Mihailov, Isaac S. Kohane
Publikováno v:
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Escott-Price, V, Kiadeh, F H F, Finucane, H K, Forstner, A J, Frank, J, Hall, L S, MacIntyre, D J & Thomson, P A & Hayward, C & McIntosh, A M & Porteous, D J 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Escott-Price, V, Grove, J, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Qvist, P, Yang, J, Mors, O, Mortensen, P B, Nordentoft, M, Werge, T, Børglum, A D & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature Genetics
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, DIrek, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Escott-Price, V, Kiadeh, F H F, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Giusti-Rodríguez, P, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hannon, E, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Hu, M, Hyde, C L, Ising, M, Jansen, R, Jin, F, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Lane, J M, Li, Y, Li, Y, Lind, P A, Liu, X, Lu, L, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, DI, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mill, J, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O'Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Purcell, S M, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Saeed Mirza, S, Saxena, R, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G B C, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Stockmeier, C A, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Tian, C, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van Der Auwera, S, Van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, De Geus, E C J, Depaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Hinds, D A, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P F A, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O'Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Winslow, A R, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D & Sullivan, P F 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature genetics 50(5), 668-681 (2018). doi:10.1038/s41588-018-0090-3
NATURE GENETICS
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, DIrek, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Smit, J H, Willemsen, G, Boomsma, D I & Penninx, B W J H 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature genetics, 50(5), 668-681. Nature Publishing Group
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Eley, T C, Gaspar, H A, Hansen, T F, Li, Y, Mcguffin, P, Mill, J, Mullins, N, Purcell, S M, Riley, B P, Smith, D J, Tansey, K E, Traylor, M, Uher, R, Lewis, C M & Breen, G & O'Reilly, P F 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature Genetics, 50(5), 668-681. Nature Publishing Group
Nature Genetics, 50(5), 668-+. Nature Publishing Group
Nature Genetics, 50(5), 668
Nature genetics
Nature genetics, vol. 50, no. 5, pp. 668-681
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T-K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Escott-Price, V, Grove, J, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Qvist, P, Yang, J, Mors, O, Mortensen, P B, Nordentoft, M, Werge, T, Børglum, A D & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature Genetics
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, DIrek, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Escott-Price, V, Kiadeh, F H F, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Giusti-Rodríguez, P, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hannon, E, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Hu, M, Hyde, C L, Ising, M, Jansen, R, Jin, F, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Lane, J M, Li, Y, Li, Y, Lind, P A, Liu, X, Lu, L, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, DI, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mill, J, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O'Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Purcell, S M, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Saeed Mirza, S, Saxena, R, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G B C, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Stockmeier, C A, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Tian, C, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van Der Auwera, S, Van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, De Geus, E C J, Depaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Hinds, D A, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P F A, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O'Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Winslow, A R, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D & Sullivan, P F 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature genetics 50(5), 668-681 (2018). doi:10.1038/s41588-018-0090-3
NATURE GENETICS
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, DIrek, N, Dolan, C V, Dunn, E C, Eley, T C, Eriksson, N, Hottenga, J J, Jansen, R, Mbarek, H, Middeldorp, C M, Milaneschi, Y, Nivard, M G, Posthuma, D, Smit, J H, Willemsen, G, Boomsma, D I & Penninx, B W J H 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature genetics, 50(5), 668-681. Nature Publishing Group
Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T M F, Bacanu, S-A, Bækvad-Hansen, M, Beekman, A F T, Bigdeli, T B, Binder, E B, Blackwood, D R H, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T, Coleman, J I R, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Crowley, C A, Dashti, H S, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Eley, T C, Gaspar, H A, Hansen, T F, Li, Y, Mcguffin, P, Mill, J, Mullins, N, Purcell, S M, Riley, B P, Smith, D J, Tansey, K E, Traylor, M, Uher, R, Lewis, C M & Breen, G & O'Reilly, P F 2018, ' Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression ', Nature Genetics, vol. 50, no. 5, pp. 668-681 . https://doi.org/10.1038/s41588-018-0090-3
Nature Genetics, 50(5), 668-681. Nature Publishing Group
Nature Genetics, 50(5), 668-+. Nature Publishing Group
Nature Genetics, 50(5), 668
Nature genetics
Nature genetics, vol. 50, no. 5, pp. 668-681
Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened\ud risk of suicide. We conducted a genome-wide association meta-analysis based in 135,458 cases and 344,901 controls and ident
Autor:
Gail Davies, Max Lam, Sarah E. Harris, Joey W. Trampush, Michelle Luciano, W. David Hill, Saskia P. Hagenaars, Stuart J. Ritchie, Riccardo E. Marioni, Chloe Fawns-Ritchie, David C. M. Liewald, Judith A. Okely, Ari V. Ahola-Olli, Catriona L. K. Barnes, Lars Bertram, Joshua C. Bis, Katherine E. Burdick, Andrea Christoforou, Pamela DeRosse, Srdjan Djurovic, Thomas Espeseth, Stella Giakoumaki, Sudheer Giddaluru, Daniel E. Gustavson, Caroline Hayward, Edith Hofer, M. Arfan Ikram, Robert Karlsson, Emma Knowles, Jari Lahti, Markus Leber, Shuo Li, Karen A. Mather, Ingrid Melle, Derek Morris, Christopher Oldmeadow, Teemu Palviainen, Antony Payton, Raha Pazoki, Katja Petrovic, Chandra A. Reynolds, Muralidharan Sargurupremraj, Markus Scholz, Jennifer A. Smith, Albert V. Smith, Natalie Terzikhan, Anbupalam Thalamuthu, Stella Trompet, Sven J. van der Lee, Erin B. Ware, B. Gwen Windham, Margaret J. Wright, Jingyun Yang, Jin Yu, David Ames, Najaf Amin, Philippe Amouyel, Ole A. Andreassen, Nicola J. Armstrong, Amelia A. Assareh, John R. Attia, Deborah Attix, Dimitrios Avramopoulos, David A. Bennett, Anne C. Böhmer, Patricia A. Boyle, Henry Brodaty, Harry Campbell, Tyrone D. Cannon, Elizabeth T. Cirulli, Eliza Congdon, Emily Drabant Conley, Janie Corley, Simon R. Cox, Anders M. Dale, Abbas Dehghan, Danielle Dick, Dwight Dickinson, Johan G. Eriksson, Evangelos Evangelou, Jessica D. Faul, Ian Ford, Nelson A. Freimer, He Gao, Ina Giegling, Nathan A. Gillespie, Scott D. Gordon, Rebecca F. Gottesman, Michael E. Griswold, Vilmundur Gudnason, Tamara B. Harris, Annette M. Hartmann, Alex Hatzimanolis, Gerardo Heiss, Elizabeth G. Holliday, Peter K. Joshi, Mika Kähönen, Sharon L. R. Kardia, Ida Karlsson, Luca Kleineidam, David S. Knopman, Nicole A. Kochan, Bettina Konte, John B. Kwok, Stephanie Le Hellard, Teresa Lee, Terho Lehtimäki, Shu-Chen Li, Christina M. Lill, Tian Liu, Marisa Koini, Edythe London, Will T. Longstreth, Oscar L. Lopez, Anu Loukola, Tobias Luck, Astri J. Lundervold, Anders Lundquist, Leo-Pekka Lyytikäinen, Nicholas G. Martin, Grant W. Montgomery, Alison D. Murray, Anna C. Need, Raymond Noordam, Lars Nyberg, William Ollier, Goran Papenberg, Alison Pattie, Ozren Polasek, Russell A. Poldrack, Bruce M. Psaty, Simone Reppermund, Steffi G. Riedel-Heller, Richard J. Rose, Jerome I. Rotter, Panos Roussos, Suvi P. Rovio, Yasaman Saba, Fred W. Sabb, Perminder S. Sachdev, Claudia L. Satizabal, Matthias Schmid, Rodney J. Scott, Matthew A. Scult, Jeannette Simino, P. Eline Slagboom, Nikolaos Smyrnis, Aïcha Soumaré, Nikos C. Stefanis, David J. Stott, Richard E. Straub, Kjetil Sundet, Adele M. Taylor, Kent D. Taylor, Ioanna Tzoulaki, Christophe Tzourio, André Uitterlinden, Veronique Vitart, Aristotle N. Voineskos, Jaakko Kaprio, Michael Wagner, Holger Wagner, Leonie Weinhold, K. Hoyan Wen, Elisabeth Widen, Qiong Yang, Wei Zhao, Hieab H. H. Adams, Dan E. Arking, Robert M. Bilder, Panos Bitsios, Eric Boerwinkle, Ornit Chiba-Falek, Aiden Corvin, Philip L. De Jager, Stéphanie Debette, Gary Donohoe, Paul Elliott, Annette L. Fitzpatrick, Michael Gill, David C. Glahn, Sara Hägg, Narelle K. Hansell, Ahmad R. Hariri, M. Kamran Ikram, J. Wouter Jukema, Eero Vuoksimaa, Matthew C. Keller, William S. Kremen, Lenore Launer, Ulman Lindenberger, Aarno Palotie, Nancy L. Pedersen, Neil Pendleton, David J. Porteous, Katri Räikkönen, Olli T. Raitakari, Alfredo Ramirez, Ivar Reinvang, Igor Rudan, Dan Rujescu, Reinhold Schmidt, Helena Schmidt, Peter W. Schofield, Peter R. Schofield, John M. Starr, Vidar M. Steen, Julian N. Trollor, Steven T. Turner, Cornelia M. Van Duijn, Arno Villringer, Daniel R. Weinberger, David R. Weir, James F. Wilson, Anil Malhotra, Andrew M. McIntosh, Catharine R. Gale, Sudha Seshadri, Thomas H. Mosley, Jan Bressler, Todd Lencz, Ian J. Deary
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications 9(1), 2098 (2018). doi:10.1038/s41467-018-04362-x
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.2098. ⟨10.1038/s41467-018-04362-x⟩
Davies, G, Lam, M, Harris, S E, Trampush, J W, Luciano, M, Hill, W D, Hagenaars, S P, Ritchie, S J, Marioni, R E, Fawns-ritchie, C, Liewald, D C M, Okely, J A, Ahola-olli, A V, Barnes, C L K, Bertram, L, Bis, J C, Burdick, K E, Christoforou, A, Derosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, D E, Hayward, C, Hofer, E, Ikram, M A, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, K A, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, C A, Sargurupremraj, M, Scholz, M, Smith, J A, Smith, A V, Terzikhan, N, Thalamuthu, A, Trompet, S, Van Der Lee, S J, Ware, E B, Windham, B G, Wright, M J, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, O A, Armstrong, N J, Assareh, A A, Attia, J R, Attix, D, Avramopoulos, D, Bennett, D A, Böhmer, A C, Boyle, P A, Brodaty, H, Campbell, H, Cannon, T D, Cirulli, E T, Congdon, E, Conley, E D, Corley, J, Cox, S R, Dale, A M, Dehghan, A, Dick, D, Dickinson, D, Eriksson, J G, Evangelou, E, Faul, J D, Ford, I, Freimer, N A, Gao, H, Giegling, I, Gillespie, N A, Gordon, S D, Gottesman, R F, Griswold, M E, Gudnason, V, Harris, T B, Hartmann, A M, Hatzimanolis, A, Heiss, G, Holliday, E G, Joshi, P K, Kähönen, M, Kardia, S L R, Karlsson, I, Kleineidam, L, Knopman, D S, Kochan, N A, Konte, B, Kwok, J B, Le Hellard, S, Lee, T, Lehtimäki, T, Li, S, Liu, T, Koini, M, London, E, Longstreth, W T, Lopez, O L, Loukola, A, Luck, T, Lundervold, A J, Lundquist, A, Lyytikäinen, L, Martin, N G, Montgomery, G W, Murray, A D, Need, A C, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, R A, Psaty, B M, Reppermund, S, Riedel-heller, S G, Rose, R J, Rotter, J I, Roussos, P, Rovio, S P, Saba, Y, Sabb, F W, Sachdev, P S, Satizabal, C L, Schmid, M, Scott, R J, Scult, M A, Simino, J, Slagboom, P E, Smyrnis, N, Soumaré, A, Stefanis, N C, Stott, D J, Straub, R E, Sundet, K, Taylor, A M, Taylor, K D, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, A N, Kaprio, J, Wagner, M, Wagner, H, Weinhold, L, Wen, K H, Widen, E, Yang, Q, Zhao, W, Adams, H H H, Arking, D E, Bilder, R M, Bitsios, P, Boerwinkle, E, Chiba-falek, O, Corvin, A, De Jager, P L, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, A L, Gill, M, Glahn, D C, Hägg, S, Hansell, N K, Hariri, A R, Ikram, M K, Jukema, J W, Vuoksimaa, E, Keller, M C, Kremen, W S, Launer, L, Lindenberger, U, Palotie, A, Pedersen, N L, Pendleton, N, Porteous, D J, Räikkönen, K, Raitakari, O T, Ramirez, A, Reinvang, I, Rudan, I, Dan Rujescu, Schmidt, R, Schmidt, H, Schofield, P W, Schofield, P R, Starr, J M, Steen, V M, Trollor, J N, Turner, S T, Van Duijn, C M, Villringer, A, Weinberger, D R, Weir, D R, Wilson, J F, Malhotra, A, Mcintosh, A M, Gale, C R, Seshadri, S, Mosley, T H, Bressler, J, Lencz, T & Deary, I J 2018, ' Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ', Nature Communications, vol. 9, no. 1, 2098 . https://doi.org/10.1038/s41467-018-04362-x
Nature Communications, 9
Nature Communications, 9:2098. Nature Publishing Group
Davies, G, Lam, M, Harris, S E, Trampush, J W, Luciano, M, Hill, W D, Hagenaars, S P, Ritchie, S J, Marioni, R E, Fawns-Ritchie, C, Liewald, D C M, Okely, J A, Ahola-Olli, A V, Barnes, C L K, Bertram, L, Bis, J C, Burdick, K E, Christoforou, A, DeRosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, D E, Hayward, C, Hofer, E, Ikram, M A, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, K A, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, C A, Sargurupremraj, M, Scholz, M, Smith, J A, Smith, A V, Terzikhan, N, Thalamuthu, A, Trompet, S, van der Lee, S J, Ware, E B, Windham, B G, Wright, M J, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, O A, Armstrong, N J, Assareh, A A, Attia, J R, Attix, D, Avramopoulos, D, Bennett, D A, Böhmer, A C, Boyle, P A, Brodaty, H, Campbell, H, Cannon, T D, Cirulli, E T, Congdon, E, Conley, E D, Corley, J, Cox, S R, Dale, A M, Dehghan, A, Dick, D, Dickinson, D, Eriksson, J G, Evangelou, E, Faul, J D, Ford, I, Freimer, N A, Gao, H, Giegling, I, Gillespie, N A, Gordon, S D, Gottesman, R F, Griswold, M E, Gudnason, V, Harris, T B, Hartmann, A M, Hatzimanolis, A, Heiss, G, Holliday, E G, Joshi, P K, Kähönen, M, Kardia, S L R, Karlsson, I, Kleineidam, L, Knopman, D S, Kochan, N A, Konte, B, Kwok, J B, Le Hellard, S, Lee, T, Lehtimäki, T, Li, S-C, Liu, T, Koini, M, London, E, Longstreth, W T, Lopez, O L, Loukola, A, Luck, T, Lundervold, A J, Lundquist, A, Lyytikäinen, L-P, Martin, N G, Montgomery, G W, Murray, A D, Need, A C, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, R A, Psaty, B M, Reppermund, S, Riedel-Heller, S G, Rose, R J, Rotter, J I, Roussos, P, Rovio, S P, Saba, Y, Sabb, F W, Sachdev, P S, Satizabal, C L, Schmid, M, Scott, R J, Scult, M A, Simino, J, Slagboom, P E, Smyrnis, N, Soumaré, A, Stefanis, N C, Stott, D J, Straub, R E, Sundet, K, Taylor, A M, Taylor, K D, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, A N, Kaprio, J, Wagner, M, Wagner, H, Weinhold, L, Wen, K H, Widen, E, Yang, Q, Zhao, W, Adams, H H H, Arking, D E, Bilder, R M, Bitsios, P, Boerwinkle, E, Chiba-Falek, O, Corvin, A, De Jager, P L, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, A L, Gill, M, Glahn, D C, Hägg, S, Hansell, N K, Hariri, A R, Ikram, M K, Jukema, J W, Vuoksimaa, E, Keller, M C, Kremen, W S, Launer, L, Lindenberger, U, Palotie, A, Pedersen, N L, Pendleton, N, Porteous, D J, Räikkönen, K, Raitakari, O T, Ramirez, A, Reinvang, I, Rudan, I, Dan Rujescu, Schmidt, R, Schmidt, H, Schofield, P W, Starr, J M, Steen, V M, Trollor, J N, Turner, S T, Van Duijn, C M, Villringer, A, Weinberger, D R, Weir, D R, Wilson, J F, Malhotra, A, McIntosh, A M, Gale, C R, Seshadri, S, Mosley, T H, Bressler, J, Lencz, T & Deary, I J 2018, ' Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ', Nature Communications, vol. 9, no. 1, pp. 2098 . https://doi.org/10.1038/s41467-018-04362-x
Nature Communications 9(1), 2098 (2018). doi:10.1038/s41467-018-04362-x
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.2098. ⟨10.1038/s41467-018-04362-x⟩
Davies, G, Lam, M, Harris, S E, Trampush, J W, Luciano, M, Hill, W D, Hagenaars, S P, Ritchie, S J, Marioni, R E, Fawns-ritchie, C, Liewald, D C M, Okely, J A, Ahola-olli, A V, Barnes, C L K, Bertram, L, Bis, J C, Burdick, K E, Christoforou, A, Derosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, D E, Hayward, C, Hofer, E, Ikram, M A, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, K A, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, C A, Sargurupremraj, M, Scholz, M, Smith, J A, Smith, A V, Terzikhan, N, Thalamuthu, A, Trompet, S, Van Der Lee, S J, Ware, E B, Windham, B G, Wright, M J, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, O A, Armstrong, N J, Assareh, A A, Attia, J R, Attix, D, Avramopoulos, D, Bennett, D A, Böhmer, A C, Boyle, P A, Brodaty, H, Campbell, H, Cannon, T D, Cirulli, E T, Congdon, E, Conley, E D, Corley, J, Cox, S R, Dale, A M, Dehghan, A, Dick, D, Dickinson, D, Eriksson, J G, Evangelou, E, Faul, J D, Ford, I, Freimer, N A, Gao, H, Giegling, I, Gillespie, N A, Gordon, S D, Gottesman, R F, Griswold, M E, Gudnason, V, Harris, T B, Hartmann, A M, Hatzimanolis, A, Heiss, G, Holliday, E G, Joshi, P K, Kähönen, M, Kardia, S L R, Karlsson, I, Kleineidam, L, Knopman, D S, Kochan, N A, Konte, B, Kwok, J B, Le Hellard, S, Lee, T, Lehtimäki, T, Li, S, Liu, T, Koini, M, London, E, Longstreth, W T, Lopez, O L, Loukola, A, Luck, T, Lundervold, A J, Lundquist, A, Lyytikäinen, L, Martin, N G, Montgomery, G W, Murray, A D, Need, A C, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, R A, Psaty, B M, Reppermund, S, Riedel-heller, S G, Rose, R J, Rotter, J I, Roussos, P, Rovio, S P, Saba, Y, Sabb, F W, Sachdev, P S, Satizabal, C L, Schmid, M, Scott, R J, Scult, M A, Simino, J, Slagboom, P E, Smyrnis, N, Soumaré, A, Stefanis, N C, Stott, D J, Straub, R E, Sundet, K, Taylor, A M, Taylor, K D, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, A N, Kaprio, J, Wagner, M, Wagner, H, Weinhold, L, Wen, K H, Widen, E, Yang, Q, Zhao, W, Adams, H H H, Arking, D E, Bilder, R M, Bitsios, P, Boerwinkle, E, Chiba-falek, O, Corvin, A, De Jager, P L, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, A L, Gill, M, Glahn, D C, Hägg, S, Hansell, N K, Hariri, A R, Ikram, M K, Jukema, J W, Vuoksimaa, E, Keller, M C, Kremen, W S, Launer, L, Lindenberger, U, Palotie, A, Pedersen, N L, Pendleton, N, Porteous, D J, Räikkönen, K, Raitakari, O T, Ramirez, A, Reinvang, I, Rudan, I, Dan Rujescu, Schmidt, R, Schmidt, H, Schofield, P W, Schofield, P R, Starr, J M, Steen, V M, Trollor, J N, Turner, S T, Van Duijn, C M, Villringer, A, Weinberger, D R, Weir, D R, Wilson, J F, Malhotra, A, Mcintosh, A M, Gale, C R, Seshadri, S, Mosley, T H, Bressler, J, Lencz, T & Deary, I J 2018, ' Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ', Nature Communications, vol. 9, no. 1, 2098 . https://doi.org/10.1038/s41467-018-04362-x
Nature Communications, 9
Nature Communications, 9:2098. Nature Publishing Group
Davies, G, Lam, M, Harris, S E, Trampush, J W, Luciano, M, Hill, W D, Hagenaars, S P, Ritchie, S J, Marioni, R E, Fawns-Ritchie, C, Liewald, D C M, Okely, J A, Ahola-Olli, A V, Barnes, C L K, Bertram, L, Bis, J C, Burdick, K E, Christoforou, A, DeRosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, D E, Hayward, C, Hofer, E, Ikram, M A, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, K A, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, C A, Sargurupremraj, M, Scholz, M, Smith, J A, Smith, A V, Terzikhan, N, Thalamuthu, A, Trompet, S, van der Lee, S J, Ware, E B, Windham, B G, Wright, M J, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, O A, Armstrong, N J, Assareh, A A, Attia, J R, Attix, D, Avramopoulos, D, Bennett, D A, Böhmer, A C, Boyle, P A, Brodaty, H, Campbell, H, Cannon, T D, Cirulli, E T, Congdon, E, Conley, E D, Corley, J, Cox, S R, Dale, A M, Dehghan, A, Dick, D, Dickinson, D, Eriksson, J G, Evangelou, E, Faul, J D, Ford, I, Freimer, N A, Gao, H, Giegling, I, Gillespie, N A, Gordon, S D, Gottesman, R F, Griswold, M E, Gudnason, V, Harris, T B, Hartmann, A M, Hatzimanolis, A, Heiss, G, Holliday, E G, Joshi, P K, Kähönen, M, Kardia, S L R, Karlsson, I, Kleineidam, L, Knopman, D S, Kochan, N A, Konte, B, Kwok, J B, Le Hellard, S, Lee, T, Lehtimäki, T, Li, S-C, Liu, T, Koini, M, London, E, Longstreth, W T, Lopez, O L, Loukola, A, Luck, T, Lundervold, A J, Lundquist, A, Lyytikäinen, L-P, Martin, N G, Montgomery, G W, Murray, A D, Need, A C, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, R A, Psaty, B M, Reppermund, S, Riedel-Heller, S G, Rose, R J, Rotter, J I, Roussos, P, Rovio, S P, Saba, Y, Sabb, F W, Sachdev, P S, Satizabal, C L, Schmid, M, Scott, R J, Scult, M A, Simino, J, Slagboom, P E, Smyrnis, N, Soumaré, A, Stefanis, N C, Stott, D J, Straub, R E, Sundet, K, Taylor, A M, Taylor, K D, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, A N, Kaprio, J, Wagner, M, Wagner, H, Weinhold, L, Wen, K H, Widen, E, Yang, Q, Zhao, W, Adams, H H H, Arking, D E, Bilder, R M, Bitsios, P, Boerwinkle, E, Chiba-Falek, O, Corvin, A, De Jager, P L, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, A L, Gill, M, Glahn, D C, Hägg, S, Hansell, N K, Hariri, A R, Ikram, M K, Jukema, J W, Vuoksimaa, E, Keller, M C, Kremen, W S, Launer, L, Lindenberger, U, Palotie, A, Pedersen, N L, Pendleton, N, Porteous, D J, Räikkönen, K, Raitakari, O T, Ramirez, A, Reinvang, I, Rudan, I, Dan Rujescu, Schmidt, R, Schmidt, H, Schofield, P W, Starr, J M, Steen, V M, Trollor, J N, Turner, S T, Van Duijn, C M, Villringer, A, Weinberger, D R, Weir, D R, Wilson, J F, Malhotra, A, McIntosh, A M, Gale, C R, Seshadri, S, Mosley, T H, Bressler, J, Lencz, T & Deary, I J 2018, ' Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ', Nature Communications, vol. 9, no. 1, pp. 2098 . https://doi.org/10.1038/s41467-018-04362-x
Publisher's version (útgefin grein)
General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, an
General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, an
Autor:
Takashi Saito, Gui-Qiu Yu, Weikun Guo, Anna G. Orr, Anthony Knox, Kaitlyn Ho, Carlee Toddes, Xin Wang, Jeffrey Simms, Daniel Kim, Takaomi C. Saido, Heike Schumacher, Iris Lo, Michael Gill, Lennart Mucke
Publikováno v:
Neurobiology of Disease, Vol 110, Iss, Pp 29-36 (2018)
Adenosine A2A receptors are putative therapeutic targets for neurological disorders. The adenosine A2A receptor antagonist istradefylline is approved in Japan for Parkinson’s disease and is being tested in clinical trials for this condition elsewhe