Zobrazeno 1 - 10
of 44
pro vyhledávání: '"M. Solis"'
Autor:
Dapeng Hao, Guangchun Han, Ansam Sinjab, Lorena Isabel Gomez-Bolanos, Rossana Lazcano, Alejandra Serrano, Sharia D. Hernandez, Enyu Dai, Xuanye Cao, Jian Hu, Minghao Dang, Ruiping Wang, Yanshuo Chu, Xingzhi Song, Jianhua Zhang, Edwin R. Parra, Jennifer A. Wargo, Stephen G. Swisher, Tina Cascone, Boris Sepesi, Andrew P. Futreal, Mingyao Li, Steven M. Dubinett, Junya Fujimoto, Luisa M. Solis Soto, Ignacio I. Wistuba, Christopher S. Stevenson, Avrum Spira, Shabnam Shalapour, Humam Kadara, Linghua Wang
Publikováno v:
Cancer Discov
Tumor-infiltrating B and plasma cells (TIB) are prevalent in lung adenocarcinoma (LUAD); however, they are poorly characterized. We performed paired single-cell RNA and B-cell receptor (BCR) sequencing of 16 early-stage LUADs and 47 matching multireg
Autor:
Maya Hassane, Zahraa Rahal, Nareg Karaoghlanian, Jiexin Zhang, Ansam Sinjab, Justin W. Wong, Wei Lu, Paul Scheet, J. Jack Lee, Maria Gabriela Raso, Luisa M. Solis, Junya Fujimoto, Hassan Chami, Alan L. Shihadeh, Humam Kadara
Publikováno v:
Cancer Prev Res (Phila)
Effects of waterpipe smoking on lung pathobiology and carcinogenesis remain sparse despite the worldwide emergence of this tobacco vector. To address this gap, we investigated the effects of chronic waterpipe smoke (WPS) exposure on lung pathobiology
Autor:
Guangchun Han, Warapen Treekitkarnmongkol, Ansam Sinjab, Tina Cascone, Jichao Chen, Humam Kadara, Ignacio I. Wistuba, Christopher S. Stevenson, Paul Scheet, Edwin R. Parra, Patrick M. Brennan, Luisa M. Solis, Carmen Behrens, Daniel G. Rosen, Jianjun Zhang, Danielle R. Little, Dapeng Hao, Beatriz Sanchez-Espiridion, Ruiping Wang, Linh M. Tran, Kostyantyn Krysan, Junya Fujimoto, John V. Heymach, Seyed Javad Moghaddam, Kieko Hara, Samer Bazzi, Minghao Dang, Avrum Spira, Kyle Chang, Dzifa Y. Duose, Don L. Gibbons, Boris Sepesi, Steven M. Dubinett, Linghua Wang, Elena Bogatenkova, Edwin J. Ostrin, Maria Gabriela Raso, Lauren Averett Byers, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Junya Fukuoka
Publikováno v:
Cancer Discov
Little is known of the geospatial architecture of individual cell populations in lung adenocarcinoma (LUAD) evolution. Here, we perform single-cell RNA sequencing of 186,916 cells from five early-stage LUADs and 14 multiregion normal lung tissues of
Autor:
Tieling Zhou, Lin Tian, Melisa Martinez-Paniagua, Rama Soundararajan, Jeffrey T. Chang, Luisa M. Solis, Barbara Mino, Sevinj Isgandarova, Ignacio I. Wistuba, Don L. Gibbons, Kendra Allton, Robiya Joseph, Xiang Zhang, Jaime Rodriguez-Canales, Michelle Craig Barton, Anil K. Sood, Crystal S. Shin, Fei Yang, Aysegul A. Sahin, Monika Haemmerle, Juri G. Gelovani, Petra den Hollander, Ghanashyam Acharya, Sendurai A. Mani, Jeffrey M. Rosen, Suhas Vasaikar, Navin Varadarajan
Publikováno v:
British Journal of Cancer
Background The mechanism by which immune cells regulate metastasis is unclear. Understanding the role of immune cells in metastasis will guide the development of treatments improving patient survival. Methods We used syngeneic orthotopic mouse tumour
Autor:
Cheuk Hong Leung, Wayne L. Hofstetter, John V. Heymach, Alexandre Reuben, Myrna C.B. Godoy, Ara A. Vaporciyan, Padmanee Sharma, Yasir Elamin, Neda Kalhor, Robert R. Jenq, Junya Fujimoto, Tina Cascone, Anne S. Tsao, William N. William, Charles Lu, Frank E. Mott, Nadim J. Ajami, Don L. Gibbons, Jack A. Roth, David C. Rice, Luisa M. Solis, Hai T. Tran, Brett W. Carter, Lauren Averett Byers, Andrew Futreal, Lorenzo Federico, Annikka Weissferdt, Garrett L. Walsh, Reza J. Mehran, Chantale Bernatchez, George R. Blumenschein, Jennifer A. Wargo, Heather Lin, Cara Haymaker, Xiuning Le, Jonathan M. Kurie, Mehmet Altan, James P. Allison, Stephen G. Swisher, Edwin R. Parra, Boris Sepesi, Hitoshi Dejima, Frank V. Fossella, Jianjun Zhang, Bonnie S. Glisson, Mara B. Antonoff, Abdul Wadud Khan, Apar Pataer, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Humam Kadara, J. Jack Lee, Ferdinandos Skoulidis
Publikováno v:
Nat Med
Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-small cell lung cancer (NSCLC), but its efficacy and impact on the immune microenvironment in operable NSCLC remain unclear. We report the results of the phase 2 ran
Autor:
Robert Tyler Hillman, Gloria Salvo, Preetha Ramalingam, Lauren Averett Byers, Junya Fujimoto, Robert J. Cardnell, Natacha Phoolcharoen, Luisa M. Solis Soto, Matthew Carroll, Michael Frumovitz
Publikováno v:
Int J Gynecol Cancer
ObjectivesWomen with recurrent high-grade neuroendocrine cervical cancer have few effective treatment options. The aim of this study was to identify potential therapeutic targets for women with this disease.MethodsSpecimens from patients with high-gr
Autor:
Sharia Hernandez, Edwin Roger Parra, Naohiro Uraoka, Ximing Tang, Yu Shen, Wei Qiao, Mei Jiang, Shanyu Zhang, Barbara Mino, Wei Lu, Renganayaki Pandurengan, Cara Haymaker, Kajsa Affolter, Courtney L. Scaife, Michele Yip-Schneider, C. Max Schmidt, Matthew A. Firpo, Sean J. Mulvihill, Eugene J. Koay, Huamin Wang, Ignacio I. Wistuba, Anirban Maitra, Luisa M. Solis, Subrata Sen
Publikováno v:
Clin Cancer Res
Purpose: Intraductal papillary mucinous neoplasms (IPMN) are bona fide precursors to pancreatic ductal adenocarcinoma (PDAC). While genomic alterations during multistep IPMN progression have been well cataloged, the accompanying changes within the tu
Autor:
Ignacio I. Wistuba, J. Jack Lee, Heladio Ibarguen, Maria C. Ferrufino-Schmidt, Cara Haymaker, Jiexin Zhang, Auriole Tamegnon, Luisa M. Solis, Edwin R. Parra, Mei Jiang, Chantale Bernatchez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Multiplex immunofluorescence (mIF) has arisen as an important tool for immuno-profiling tumor tissues. We updated our manual protocol into an automated protocol that allows the use of up to seven markers in five mIF panels to apply to formalin-fixed
Autor:
Guillermo Garcia-Manero, Dapeng Hao, Edwin R. Parra, Jairo T. Mathews, Naval Daver, Patrick K. Reville, Padmanee Sharma, Auriole Tamegnon, Latasha Little, Koichi Takahashi, Kunal Rai, Jin Seon Im, Feng Wang, Hussein A. Abbas, Wei Wang, Luisa M. Solis, Maomao Ding, Sreyashi Basu, Michael R. Green, Marina Konopleva, James P. Allison, Katarzyna Tomczak, Zoe Alaniz, Gheath Alatrash, Jing Ning, Wei Lu, Mario L. Marques-Piubelli, Andrew Futreal, Steven M. Kornblau, Hannah C. Beird, Praveen Barrodia, Ruiping Wang, Linghua Wang, Jianhua Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In contrast to the curative effect of allogenic stem cell transplantation in acute myeloid leukemia via T cell activity, only modest responses are achieved with checkpoint-blockade therapy, which might be explained by T cell phenotypes and T cell rec
Autor:
Guangchun, Han, Ansam, Sinjab, Kieko, Hara, Warapen, Treekitkarnmongkol, Patrick, Brennan, Kyle, Chang, Elena, Bogatenkova, Beatriz, Sanchez-Espiridion, Carmen, Behrens, Luisa M, Solis, Boning, Gao, Luc, Girard, Jianjun, Zhang, Boris, Sepesi, Tina, Cascone, Lauren A, Byers, Don L, Gibbons, Jichao, Chen, Seyed Javad, Moghaddam, Edwin J, Ostrin, Paul, Scheet, Junya, Fujimoto, Jerry, Shay, John V, Heymach, John D, Minna, Steven, Dubinett, Ignacio I, Wistuba, Christopher S, Stevenson, Avrum E, Spira, Linghua, Wang, Humam, Kadara
Publikováno v:
Cancers
Simple Summary The coronavirus disease 2019 (COVID-19) pandemic continues to spread rapidly on a global scale. When presenting with severe respiratory complications, COVID-19 results in markedly high death rates, particularly among patients with como