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Autor:
Crossley, Magdalena P., Song, Chenlin, Bocek, Michael J., Choi, Jun Hyuk, Kousorous, Joseph, Sathirachinda, Ataya, Lin, Cindy, Brickner, Joshua R., Bai, Gongshi, Lans, Hannes, Vermeulen, Wim, Abu-Remaileh, Monther, Cimprich, Karlene A., Kanaar, Roland
Publikováno v:
Nature, 613(7942), 187-194. Nature Publishing Group
Nature
Nature
R-loops are RNA–DNA-hybrid-containing nucleic acids with important cellular roles. Deregulation of R-loop dynamics can lead to DNA damage and genome instability1, which has been linked to the action of endonucleases such as XPG2–4. However, the m