Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Huaxin Sheng"'
Autor:
Ulrike Hoffmann, Liping Lu, Xuan Li, Zhuoran Wang, Huaxin Sheng, Ran Li, Wei Yang, Yuntian Shen
Publikováno v:
Shock
After cardiac arrest (CA) and resuscitation, the unfolded protein response (UPR) is activated in various organs including the brain. However, the role of the UPR in CA outcome remains largely unknown. One UPR branch involves spliced X-box-binding pro
Autor:
Huaxin Sheng, Jingjun Lyu, Francesca Galeffi, Dennis A. Turner, Wulf Paschen, Zhuoran Wang, Joshua D. Bernstock, Yuntian Shen, Shu Yu, Shuai Liu, Wei Yang, Ramona M. Rodriguiz, Kory R. Johnson, Ran Li, William C. Wetsel
Publikováno v:
FASEB J
Small ubiquitin-like modifier (SUMO1–3) conjugation (SUMOylation), a post-translational modification, modulates almost all major cellular processes. Mounting evidence indicates that SUMOylation plays a crucial role in maintaining and regulating neu
Publikováno v:
Stroke
Background and Purpose— Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which
Autor:
Junjie Yao, Dong Zhang, Tri Vu, Ulrike Hoffmann, Maomao Chen, Ran Li, Huaxin Sheng, Jianwen Luo, Wei Yang
Publikováno v:
J Biophotonics
The in vivo hemodynamic impact of sodium nitroprusside (SNP), a widely used antihypertensive agent, has not been well studied. Here, we applied functional optical-resolution photoacoustic microscopy (OR-PAM) to study the hemodynamic responses to SNP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ae0a9d1c2519fa738ba6c088c1affc
https://europepmc.org/articles/PMC8263508/
https://europepmc.org/articles/PMC8263508/
Autor:
Ivan Spasojevic, Bin Xu, Romulo S. Sampaio, David S. Warner, Ines Batinic-Haberle, Huaxin Sheng, Artak Tovmasyan, Litao Li, Júlio S. Rebouças
Publikováno v:
Antioxidants, Vol 9, Iss 467, p 467 (2020)
Antioxidants
Volume 9
Issue 6
Antioxidants
Volume 9
Issue 6
Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, (H2O)MnTnHex-2-PyP5+ (MnHex) carrying long hexyl chains, is a lipophilic mimic of superoxide dismutase (SOD) and a redox-active drug candidate. MnHex crosses the blood&ndash
brain barrier
brain barrier
Autor:
Huaxin Sheng, Ying Li, Zhui Yu, Wei Yang, Meng Jiang, Shuai Liu, David S. Warner, Shu Yu, Wulf Paschen
Publikováno v:
Stroke. 48:1646-1654
Background and Purpose— Impaired protein homeostasis induced by endoplasmic reticulum dysfunction is a key feature of a variety of age-related brain diseases including stroke. To restore endoplasmic reticulum function impaired by stress, the unfold
Autor:
Huaxin Sheng, Ying Li, Wulf Paschen, Xiaozhi Liu, Shuai Liu, David S. Warner, Lin Zhang, Wei Yang, Julia Q. Zhao
Publikováno v:
Neuroscience. 343:190-212
Small ubiquitin-like modifier (SUMO) conjugation (SUMOylation) plays key roles in neurologic function in health and disease. Neuronal SUMOylation is essential for emotionality and cognition, and this pathway is dramatically activated in post-ischemic
Autor:
Wei Yang, Dennis A. Turner, Dongmei Chu, Huaxin Sheng, Ulrike Hoffmann, Jennifer A. Creed, Litao Li, Yu-Mi Ryang, David S. Warner, Shuang Ma
Publikováno v:
Crit Care Med
OBJECTIVES: We tested the hypothesis that prolonged inhalation of 70% argon for 24 hours after in-vivo permanent or temporary stroke provides neuroprotection, and improves neurologic outcome and overall recovery after 7 days. DESIGN: Controlled, rand
Autor:
Francesca Galeffi, Ya-chao Wang, Xuan Li, Wei Wang, Wei Yang, Huaxin Sheng, Ulrike Hoffmann, Dennis A. Turner, Liping Lu
Publikováno v:
Exp Neurol
Background and purpose Ischemic stroke significantly perturbs neuronal homeostasis leading to a cascade of pathologic events causing brain damage. In this study, we assessed acute stroke outcome after chemogenetic inhibition of forebrain excitatory n
Autor:
Wei Yang, Jörn Karhausen, Joshua D. Bernstock, Kory R. Johnson, Huaxin Sheng, Wulf Paschen, Yuntian Shen, John M. Hallenbeck, Qing Ma
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 98(6)
The intestinal epithelium constitutes a crucial defense to the potentially life-threatening effects of gut microbiota. However, due to a complex underlying vasculature, hypoperfusion and resultant tissue ischemia pose a particular risk to function an