Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hongbo Hu"'
Autor:
Xueying Chen, Xiaomeng Wang, Shiqian Qi, Qianqian Chen, Lunzhi Dai, Yu Qi, Hui Yu, Hongbo Hu, Wenyong Yang, Zhiwen Gu, Yanqiu Gong, Bo Zhong, Zhiqiang Zhang, Huiyuan Zhang
Publikováno v:
Cellular and Molecular Immunology
Activation of the TAK1 signalosome is crucial for mediating the innate immune response to pathogen invasion and is regulated by multiple layers of posttranslational modifications, including ubiquitination, SUMOylation, and phosphorylation; however, t
Publikováno v:
Cancers; Volume 14; Issue 2; Pages: 345
Cancers, Vol 14, Iss 345, p 345 (2022)
Cancers
Cancers, Vol 14, Iss 345, p 345 (2022)
Cancers
Simple Summary Selenite, a representative inorganic form of selenium, is preferentially accumulated in tumors. The therapeutic potential of sodium selenite in tumors has received significant attention. However, the effect of sodium selenite in the tr
Publikováno v:
Foods
Foods, Vol 10, Iss 3120, p 3120 (2021)
Foods; Volume 10; Issue 12; Pages: 3120
Foods, Vol 10, Iss 3120, p 3120 (2021)
Foods; Volume 10; Issue 12; Pages: 3120
Multiple mechanisms are involved in exercise-induced fatigue, including energy depletion, metabolite accumulation, and oxidative stress, etc. The mechanistic findings provide a rationale for a multi-targeted approach to exercise-induced fatigue manag
Publikováno v:
Biomedicines, Vol 9, Iss 939, p 939 (2021)
Biomedicines
Volume 9
Issue 8
Biomedicines
Volume 9
Issue 8
Acetaminophen (APA)-induced hepatotoxicity is coupled with the activation of autophagy. We sought to determine whether selective autophagy of the endoplasmic reticulum (ER), termed ER-phagy, is involved in APA hepatotoxicity and to explore its potent
Publikováno v:
Toxins, Vol 13, Iss 221, p 221 (2021)
Toxins
Volume 13
Issue 3
Toxins
Volume 13
Issue 3
Food can be contaminated by various types of contaminants such as mycotoxins and toxic heavy metals. Therefore, it is very likely that simultaneous intake of more than one type of food contaminant by consumers may take place, which provides a strong
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 24, Pp 15708-15715 (2021)
ACS Omega, Vol 6, Iss 24, Pp 15708-15715 (2021)
The most common saturated fatty acid in the human diet is palmitic acid (PA), and emerging evidence suggests that it may have anticancer activity. Methylseleninic acid (MSeA), the most commonly used selenium derivative in humans, has specific cytotox
Publikováno v:
Toxins
Volume 12
Issue 1
Toxins, Vol 12, Iss 1, p 55 (2020)
Volume 12
Issue 1
Toxins, Vol 12, Iss 1, p 55 (2020)
Previous studies by us or others have shown that endoplasmic reticulum (ER) stress was activated by fumonisin 1 (FB1) exposure, which is considered to be a critical event in the FB1-induced toxic effect. However, the detailed mechanisms underlying FB
Autor:
Yichuan Xiao, Isabelle Marie, Haiyan S. Li, Shao Cong Sun, Zuliang Jie, Hui Wang, Jin Jin, Ting Liu, David E. Levy, Li Zhang, Hongbo Hu, Stephanie S. Watowich, Qiang Zou, Xiaoping Xie, Xuhong Cheng, Ganiraju C. Manyam
Publikováno v:
The Journal of Experimental Medicine
Xiao et al. demonstrate that a protein kinase, TBK1, regulates the function of dendritic cells in mediating immune responses.
Dendritic cells (DCs) are crucial for mediating immune responses but, when deregulated, also contribute to immunologica
Dendritic cells (DCs) are crucial for mediating immune responses but, when deregulated, also contribute to immunologica
Autor:
Xuan Lin, Fei Wang, Shangyun Lu, Fanfan Zeng, Ping Yuan, Yang Fu, Qin Tian, Juanjuan Xiao, Lin Liu, Xinying Ji, Ruijuan Xiu, Peipei Xue, Sanpeng Xu, Qian Chu, Tengfei Ma, Xia Zhao, Hongbo Hu, Hui Lu, Ling Zou, Yuan Li, Hongtian Dai, Jianmin Zhang, Xiaofang Ni, Qiuhong Duan, Feng Zhu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 10, Pp 1-12 (2019)
Cell Death and Disease, Vol 10, Iss 10, Pp 1-12 (2019)
MET overactivation is one of the crucial reasons for tyrosine kinase inhibitor (TKI) resistance, but the mechanisms are not wholly clear. Here, COX2, TOPK, and MET expression were examined in EGFR-activating mutated NSCLC by immunohistochemical (IHC)
Autor:
Peidong Zhang, Wei Wang, Sai Zhao, Hongbo Hu, Bin Shao, Nianxin Zhou, Ryan C. Gimple, Xuehan Jiang, Yangfan Zeng, Shuang Huang, Young Ha Ahn, Jingyun Yang, Qian Zhang, Zhiwei Chen, Shengtao Zhou, Linjie Zhao, Jan-Åke Gustafsson
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101458-(2020)
iScience
iScience
Summary The emerging immune checkpoint blockade (ICB) therapy has ushered the cancer therapeutics field into an era of immunotherapy. Although ICB treatment provides remarkable clinical responses in a subset of patients with cancer, this regimen fail