Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Antao Chang"'
Autor:
Dan Wu, Dongmei Cheng, Shan Huang, Peiqing Sun, Juan Wang, Rong Xiang, Boris Pasche, Wei Zhang, Antao Chang, Guanwen Wang, Liang Liu, Stacey S O'Neill, Yanan Chen, Xiaoming Tan, William J. Petty, Justin M. Ashby
Publikováno v:
Cancer Res
When recruited to promoters, histone 3 lysine 4 (H3K4) methyltransferases KMT2 (KMT2A-D) activate transcription by opening chromatin through H3K4 methylation. Here, we report that KMT2 mutations occur frequently in non–small cell lung cancer (NSCLC
Autor:
Guanwen Wang, Juan Wang, Antao Chang, Dongmei Cheng, Shan Huang, Dan Wu, Sherona Sirkisoon, Shuang Yang, Hui-Kuan Lin, Hui-Wen Lo, Rong Xiang, Peiqing Sun
Publikováno v:
Oncogene
While mechanisms for metastasis were extensively studied in cancer cells from patients with detectable tumors, pathways underlying metastatic dissemination from early lesions before primary tumors appear are poorly understood. Her2 promotes breast ca
Autor:
Shengyu Yang, Yang Xu, Jihui Hao, Antao Chang, Hongwei Wang, Tiansuo Zhao, Yang Li, Xiuchao Wang, Jie Dong, Na Li, Keping Xie, Chongbiao Huang, Yi Ge, He Ren, Zengxun Li
Publikováno v:
Clin Cancer Res
Purpose: Oxygen and glucose deprivation is a common feature of the solid tumor. Regulatory network underlying the adaptation of cancer cells to the harsh microenvironment remains unclear. We determined the mechanistic role of LIM and senescent cell a
Autor:
Dongmei Cheng, Dan Wu, Xiaoming Tan, Shan Huang, Peiqing Sun, Qiong Wang, Rong Xiang, Shaorong Zhao, Antao Chang, Juan Wang, Guanwen Wang, Shuang Yang, Andy T Liu
Publikováno v:
Oncogene
Cancer can metastasize from early lesions without detectable tumors. Despite extensive studies on metastasis in cancer cells from patients with detectable primary tumors, mechanisms for early metastatic dissemination are poorly understood. Her2 promo
Autor:
Chongbiao Huang, Yujia Zhao, Xiaosu Chen, Yi Shi, Xiaoshuang Wang, Longlong Wang, Jia Li, Kejia Xu, Rong Xiang, Xuan Qin, Yajing Lv, Antao Chang
Publikováno v:
Cancers, Vol 13, Iss 1403, p 1403 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
Simple Summary Chemotherapeutic agents including cisplatin promote tumor metastasis while inhibiting tumor growth, which still represents a major obstacle for some patients in clinical practices. This study demonstrated that cisplatin induced epithel
Autor:
He Ren, Wei Zhang, Chongbiao Huang, Na Li, Lin Luo, Zengxun Li, Antao Chang, Yang Li, Xiuchao Wang, Shengyu Yang, Yanan Chen, Tiansuo Zhao, Zhimin Wang, Jingjing Shi, Jihui Hao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Interleukin 35 (IL-35) is a novel member of the IL-12 family, consisting of an EBV-induced gene 3 (EBI3) subunit and a P35 subunit. IL-35 is an immune-suppressive cytokine mainly produced by regulatory T cells. However, the role of IL-35 in cancer me
Autor:
Yunping Luo, Tsung-Hsien Chuang, Wenzhi Shen, Peiqing Sun, Antao Chang, Shuang Yang, Yanan Chen, Ruifang Gao, Chenghu Liu, Wei Zhou, Yanhua Liu, Rong Xiang
Publikováno v:
The Journal of infectious diseases. 212(9)
Treatment of mice with lipopolysaccharide (LPS) and the liver-specific transcriptional inhibitor D-(+)-galactosamine (GalN) induces fatal hepatitis, which is mediated by tumor necrosis factor α (TNF-α) and characterized by massive hepatic apoptosis