Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew C. Adams"'
Autor:
Krithika Muthuraman, Richard E. Higgs, Carl L. Hansen, Maren de Vries, Mark J. Mulligan, Kizzmekia S. Corbett, Ping Xiang, Nicole V. Johnson, Jory A. Goldsmith, Jason S. McLellan, John R. Mascola, Marissa H. Piper, Lucas Kraft, Jamie L. Blackbourne, Samuel J. Hinshaw, Davide Pellacani, Stefanie Žentelis, Christopher M. Wiethoff, Solmaz Sobhanifar, David R. Martinez, Franz J. Triana, Thomas P. Cujec, Barney S. Graham, Robert W. Cross, Ching-Lin Hsieh, Beverly A. Heinz, Denisa Foster, Ralph S. Baric, Sean A. Tycho, Jorg Hendle, David Collins, Eun Sung Yang, Ester Falconer, Daniel Wrapp, Andrew C. Adams, Roza Bidshahri, A. Pustilnik, Yuri Hwang, Adil Mohamed, Julian Davies, Yi Zhang, Patricia Brown-Augsburger, Bryan Edward Jones, Shawn J. Berens, Kevin R. Jepson, Bryan C. Barnhart, Kathryn Westendorf, Lingshu Wang, Viktoriya Borisevich, Meike Dittmann, Maia A. Smith, Deepa Balasubramaniam, Thomas W. Geisbert, Rodrigo Goya, Hayley M. Belli, Olubukola M. Abiona, Marie I. Samanovic
Publikováno v:
bioRxiv
Science Translational Medicine
Science Translational Medicine
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies are a key class of therapeutics that may bridge widespread vaccination
Autor:
Ruth Gordillo, Kai Sun, William L. Holland, Jonathan Y. Xia, Christine M. Kusminski, Rana K. Gupta, Chelsea Hepler, Yu An, Thomas S. Morley, Philipp E. Scherer, Alexandra L. Ghaben, Andrew C. Adams
Publikováno v:
Diabetologia. 61:932-941
AIM/HYPOTHESIS: Adiponectin (APN), a circulating hormone secreted by mature adipocytes, has been extensively studied because it has beneficial metabolic effects. While many studies have focused on the congenital loss of APN and its effects on systemi
Autor:
Andrew C. Adams, Kostas Tsintzas, Jeni Luckett, Scott Cooper, Ricardo J. Samms, Jo E. Lewis, Alan C. Perkins, Francis J. P. Ebling
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
FGF21 exerts profound metabolic effects in Siberian hamsters exposed to long day (LD) photoperiods that increase appetite and adiposity, however these effects are attenuated in short day (SD) animals that display hypophagia and reduced adiposity. The
Autor:
Pavlos Pissios, Andrew C. Adams, Gabriella Segal-Lieberman, Eleni M Domouzoglou, Melissa J. Chee, Eleftheria Maratos-Flier
Publikováno v:
Behavioural Brain Research. 224:195-200
Melanin-concentrating hormone (MCH) is an orexigenic hypothalamic neuropeptide. At least one receptor, MCH receptor 1 (MCHR1), is present in all mammals and is expressed widely throughout the brain, including cortex, striatum and structures implicate
Autor:
Andrew C. Adams, Maria Kost-Alimova, Ronald A. DePinho, Eleftheria Maratos-Flier, Shan Jiang, Alexei Protopopov, Florian L. Muller, Jihye Paik, Emily Thomas, Mariela Jaskelioff, Juan Cadiñanos, James W. Horner, Ergun Sahin
Publikováno v:
Nature
An ageing world population has fuelled interest in regenerative remedies that may stem declining organ function and maintain fitness. Unanswered is whether elimination of intrinsic instigators driving age-associated degeneration can reverse, as oppos
Autor:
Stephen E. Flaherty, Andrew C. Adams, Shuangyu Lu, Nicholas Douris, Eleftheria Maratos-Flier, Avery B. Forrow, Melissa J. Chee, Arnaud Monnard
Olanzapine (OLZ), an atypical antipsychotic, can be effective in treating patients with restricting type anorexia nervosa who exercise excessively. Clinical improvements include weight gain and reduced pathological hyperactivity. However the neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad20bd6e96e74bef866102fa3984dcd2
https://europepmc.org/articles/PMC4609648/
https://europepmc.org/articles/PMC4609648/
Autor:
Andrew C. Adams, Ruth E. Gimeno
Publikováno v:
Cell Metabolism. 23(2):227-228
Fibroblast growth factor 21 (FGF21) is a hormone induced by various metabolic stresses, including ketogenic and high carbohydrate diets, that regulates energy homeostasis. In humans, SNPs in and around the FGF21 gene have been associated with macronu
Autor:
Andrew C. Adams, Amber J. Giles, Kimberly Wong, Alexei Kharitonenkov, Qin Yang, Jianwei Jiang, Leonard Guarente, Bin Gao, Jong Woo Lee, Yu Li, Mengwei Zang
Publikováno v:
PMC
Background & Aims The hepatocyte-derived hormone fibroblast growth factor 21 (FGF21) is a hormone-like regulator of metabolism. The nicotinamide adenine dinucleotide–dependent deacetylase SIRT1 regulates fatty acid metabolism through multiple nutri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f342a098d10f2400a076e6edad67e26
https://europepmc.org/articles/PMC4228483/
https://europepmc.org/articles/PMC4228483/
Autor:
Alexei Kharitonenkov, Mark R. Wade, Joseph T. Brozinick, Hai H. Bui, Philipp E. Scherer, Yukiko Miyauchi, William L. Holland, Ming Shang Kuo, Christine M. Kusminski, Ruth Gordillo, Steven M. Bauer, Katherine Volk, Esha Singhal, Christine C. Cheng, Andrew C. Adams
SummaryFGF21, a member of the fibroblast growth factor (FGF) superfamily, has recently emerged as a regulator of metabolism and energy utilization. However, the exact mechanism(s) whereby FGF21 mediates its actions have not been elucidated. There is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f972c3e8f55d1b0b3a412c88867ef4e
https://europepmc.org/articles/PMC3667496/
https://europepmc.org/articles/PMC3667496/