Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adrian Tun Kyi"'
Autor:
Xiao Zhen Zhou, Adrian Tun Kyi, John M. Asara, Iddo Z. Ben-Dov, Elliot Israel, Koichi Kobayashi, Mohamed S. Arredouani, Linda K. Nicholson, Kun Ping Lu, Morris Nechama, Chun-Hau Chen, Jeahoo Kwon, Shuo Wei, Robert S. Welner, Kyle F. Nelson, Cheng-Yu Tsai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing cytokine
Autor:
Katherine A. Fitzgerald, John M. Asara, Linda K. Nicholson, Tae Ho Lee, George C. Tsokos, Greg Finn, Adrian Tun-Kyi, Michael Nowak, Elliot Israel, Alexander I. Greenwood, Mark A. Exley, Kun Ping Lu, Xiaoxia Li
Publikováno v:
Nature immunology
Toll-like receptors (TLRs) shape innate and adaptive immunity to microorganisms. The enzyme IRAK1 transduces signals from TLRs, but mechanisms for its activation and regulation remain unknown. We found here that TLR7 and TLR9 activated the isomerase
Autor:
Christina Y. Soohoo, Tae Ho Lee, Martin Balastik, Lucia Pastorino, Greg Finn, Gerburg M. Wulf, Xiao Zhen Zhou, Kun Ping Lu, Adrian Tun-Kyi, Jormay Lim, Rong Shi
Publikováno v:
Nature Cell Biology. 11:97-105
The prolyl isomerase Pin1 acts in various cellular processes. It has now been implicated in telomere maintenance by regulating the stability of the telomere binding protein TRF1. Telomeres are essential for maintaining cellular proliferative capacity
Autor:
Michael Gombert, Bernhard Homey, Curdin Conrad, Adrian Tun-Kyi, Yong-Jun Liu, Frank O. Nestle, Michel Gilliet, Onur Boyman, Günter Burg
Publikováno v:
The Journal of Experimental Medicine
Psoriasis is one of the most common T cell-mediated autoimmune diseases in humans. Although a role for the innate immune system in driving the autoimmune T cell cascade has been proposed, its nature remains elusive. We show that plasmacytoid predendr