Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
David Lim, Mindy K. Graham, Eva Corey, Tamara L. Lotan, Jonathan I. Epstein, Alan K. Meeker, Christopher M. Heaphy, Hao Wang, Mario A. Eisenberger, Angelo M. De Marzo, Christine Davis, Michael C. Haffner
Publikováno v:
Hum Pathol
BACKGROUND: Small cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation, however the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in
Autor:
Qizhi Zheng, Angelo M. De Marzo, Jiayu Chen, Avi Z. Rosenberg, Michael C. Haffner, Busra Ozbek, Lauren B. Peiffer, Moshe Levi, Jessica L. Hicks, Srinivasan Yegnasubramanian, Javier A. Baena Del Valle, Xiaoxin X. Wang
Publikováno v:
Am J Pathol
Mitochondria regulate ATP production, metabolism, and cell death. Alterations in mitochondrial DNA (mtDNA) sequence and copy number are implicated in aging and organ dysfunction in diverse inherited and sporadic diseases. Because most measurements of
Autor:
Jessica L. Hicks, Tamara L. Lotan, Angelo M. De Marzo, Ayanna M Carter, Lauren B. Peiffer, Luke Mummert, Rebecca Y Sosa, Jiayun Lu, Corinne E. Joshu, Karen S. Sfanos, Ryan Kempski, Igor Vidal, Tamirat Ali, Janielle P. Maynard
Publikováno v:
J Pathol
Prostate cancer (PCa) remains a leading cause of cancer-related deaths in American men and treatment options for metastatic PCa are limited. There is a critical need to identify new mechanisms that contribute to PCa progression, that distinguish beni
Autor:
Angelo M. De Marzo, Tamara L. Lotan, Michael C. Haffner, Jun Luo, Alba Torres, Srinivasan Yegnasubramanian, Juhyung Woo, Ilsa Coleman, Thiago Vidotto, Brian Hanratty, Kaushal Asrani, Peter S. Nelson, Harrison Tsai, Eva Corey
Publikováno v:
J Pathol
Neuroendocrine prostate cancer (NEPC) is a rare but aggressive histologic variant of prostate cancer that responds poorly to androgen deprivation therapy. Hybrid NEPC-adenocarcinoma (AdCa) tumors are common, often eluding accurate pathologic diagnosi
Autor:
Tamara L. Lotan, John R. Barber, Edward M. Schaeffer, Laneisha Maldonado, Angelo M. De Marzo, Corinne E. Joshu, Liana B. Guedes, Mario A. Eisenberger, Jiayun Lu, Harsimar B. Kaur, Scott A. Tomlins, Karen S. Sfanos, Logan Reitz
Publikováno v:
Hum Pathol
Summary The makeup of the tumor immune microenvironment may be associated with tumor somatic genomic alterations and plays a key role in tumor progression and response to immunotherapy. We examined the association of tumor-infiltrating T-cell density
Autor:
Janielle P. Maynard, Angelo M. De Marzo, Corey M. Porter, Karen S. Sfanos, Ibrahim Kulac, Michael C. Haffner, Javier Valle, William B. Isaacs, Srinivasan Yegnasubramanian
Publikováno v:
Am J Pathol
Lactoferrin (LTF) is an iron-binding protein canonically known for its innate and adaptive immune functions. LTF may also act as a tumor suppressor with antiproliferative action. LTF is inactivated genetically or epigenetically in various cancers, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a710a412d6ff9bc890a3ef606bfbcfb2
https://europepmc.org/articles/PMC6892185/
https://europepmc.org/articles/PMC6892185/
Autor:
Alan K. Meeker, William G. Nelson, Charles G. Drake, Srinivasan Yegnasubramanian, George J. Netto, David M. Esopi, Liana B. Guedes, Jun Luo, Kunhwa Kim, Michael C. Haffner, Tamara L. Lotan, Angelo M. De Marzo, Harrison Tsai, Gunes Guner, Doreen N. Palsgrove, Diana Taheri, Rajni Sharma, Arul M. Chinnaiyan, Rohit Mehra, Qizhi Zheng, Emmanuel S. Antonarakis
Publikováno v:
The American Journal of Pathology. 188:1478-1485
Antibodies targeting the programmed cell death protein 1/programmed death-ligand 1 (PD-L1) interaction have shown clinical activity in multiple cancer types. PD-L1 protein expression is a clinically validated predictive biomarker of response for such
Autor:
Jiayun Lu, Tamara L. Lotan, Logan Reitz, Harsimar B. Kaur, Jeffrey J. Tosoian, Angelo M. De Marzo, John R. Barber, Scott A. Tomlins, Karen S. Sfanos, Corinne E. Joshu, Edward M. Schaeffer, Liana B. Guedes, Laneisha Maldonado
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
The inflammatory microenvironment plays an important role in the pathogenesis and progression of tumors and may be associated with somatic genomic alterations. We examined the association of tumor-infiltrating T-cell density with clinical-pathologic
Autor:
Angelo M. De Marzo, Tamara L. Lotan, Jessica Hicks, Carlos L. Morais, Alexander S. Baras, Liana B. Guedes
Publikováno v:
Human Pathology. 55:117-125
High-grade prostatic intraepithelial neoplasia (HGPIN) is widely believed to represent a precursor to invasive prostatic adenocarcinoma. However, recent molecular studies have suggested that retrograde spread of invasive adenocarcinoma into pre-exist
Autor:
Yunjie Li, Pedram Argani, Doreen N. Palsgrove, Andres Matoso, Christopher D. Gocke, Ming Tseh Lin, Angelo M. De Marzo, Jonathan I. Epstein, George J. Netto, Christine A. Pratilas, Aparna Pallavajjalla
Publikováno v:
The American journal of surgical pathology. 42(9)
Eosinophilic solid and cystic (ESC) renal cell carcinoma (RCC) has recently been described as a potentially new subtype of RCC based upon morphologic and immunohistochemical features. These neoplasms typically demonstrate solid and cystic architectur