Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Crystal L Mackall"'
Autor:
Steven A. Feldman, Kara L. Davis, John H. Baird, Robert Lowsky, Rachel C. Lynn, Magali Bazzano, Judith A. Shizuru, Matthew J. Frank, Surbhi Sidana, Maria Caterina Rotiroti, Maria Iglesias, Sean Mackay, Sally Arai, Bita Sahaf, Shabnum Patel, Nirali N. Shah, Laura Johnston, Jay Y. Spiegel, Jing Zhou, Juliana Craig, Robert S. Negrin, Robbie G. Majzner, Andrew R. Rezvani, Zach Ehlinger, Ilan R. Kirsch, Parveen Shiraz, Chelsea D. Mullins, Michael G. Ozawa, Nikolaos Gkitsas, Crystal L. Mackall, Terry J. Fry, Warren D. Reynolds, Yasodha Natkunam, Sneha Ramakrishna, Scott J. Bornheimer, Allison P. Jacob, Lori Muffly, Jean Oak, Haiying Qin, Katherine A. Kong, Wen-Kai Weng, Everett Meyer, Nasheed Hossain, John S. Tamaresis, Sheren F. Younes, David B. Miklos, Liora M. Schultz, Eric J Yang, Harshini Chinnasamy
Publikováno v:
Nature Medicine
Despite impressive progress, more than 50% of patients treated with CD19-targeting chimeric antigen receptor T cells (CAR19) experience progressive disease. Ten of 16 patients with large B cell lymphoma (LBCL) with progressive disease after CAR19 tre
Autor:
Anthony A. Fodor, Erin F. Brooks, Crystal L. Mackall, Farnaz Fouladi, Matthew T. Buckley, Robert S. Negrin, Bita Sahaf, Andrew R. Rezvani, Courtney Greene, Ekaterina Tkachenko, David B. Miklos, Sally Arai, Haley Hedlin, Ami S. Bhatt, Tessa M. Andermann, Fiona B. Tamburini
Publikováno v:
Transplant Cell Ther
Alterations of the gut microbiota after allogeneic hematopoietic cell transplantation (allo-HCT) are a key factor in the development of transplant-related complications such as graft-versus-host disease (GVHD). Interventions that preserve the gut mic
Autor:
Katherine K. Matthay, Crystal L. Mackall, Phillip Barnette, Richard B. Womer, Steven G. DuBois, Douglas S. Hawkins, Elizabeth Sinclair, Stephen L. Lessnick, Richard Gorlick, Katherine A. Janeway, Jeremy V. Edwards, Donald A. Barkauskas, Kieuhoa T. Vo, Holcombe E. Grier, C. Lorrie Epling, Mark Krailo, Elizabeth McIlvaine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 22, iss 14
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma. Experimental Design: Newly diagnose
Autor:
Terry J. Fry, Crystal L. Mackall
Publikováno v:
Hematology Am Soc Hematol Educ Program
Substantial progress has been made in the treatment of precursor B-cell acute lymphoblastic leukemia (B-ALL), but recurrent disease remains a leading cause of death in children due to cancer and outcomes for adults with B-ALL remain poor. Recently, c
Autor:
Terry J. Fry, Jack H. Lai, Barry Jones, Iwona Woznica, Yuxin Liu, Najat Bouchkouj, Shannon M. Larabee, Haiying Qin, Crystal L. Mackall, Brynn B. Duncan, Steven L. Highfill, William W. Bachovchin, Wengen Wu, Youhua Li, Peng Zhao
Publikováno v:
Journal of Immunotherapy. 36:400-411
Current multimodality therapy consisting of surgery, chemotherapy and radiation will fail in approximately 40% of patients with pediatric sarcomas and results in substantial long-term morbidity in those who are cured. Immunotherapeutic regimens for t
Autor:
Jiaqiang Ren, Hanh Khuu, Minh Tran, Crystal L. Mackall, Sue Ellen Frodigh, Melinda S. Merchant, David F. Stroncek, Daniel W. Lee, Marianna Sabatino
Background aims Autologous chimeric antigen receptor (CAR) T-cell therapies have shown promising clinical outcomes, but T-cell yields have been variable. CD19- and GD2-CAR T-cell manufacturing records were reviewed to identify sources of variability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c13f850306b0fc264f7e656225e291c
https://europepmc.org/articles/PMC4898642/
https://europepmc.org/articles/PMC4898642/
Publikováno v:
Pediatric Clinics of North America. 57:83-96
One major advance in T-cell-based immunotherapy in the last 20 years has been the molecular definition of numerous viral and tumor antigens. Adoptive T-cell transfer has shown definite clinical benefit in the prophylaxis and treatment of viral infect
Publikováno v:
Annals of the New York Academy of Sciences. 1182:28-38
Interleukin-7 has critical and nonredundant roles in T cell development, hematopoiesis, and postdevelopmental immune functions as a prototypic homeostatic cytokine. Based on a large body of preclinical evidence, it may have multiple therapeutic appli
Autor:
Linda T. Vahdat, Meera Murgai, Rosandra N. Kaplan, Amber J. Giles, Steven L. Highfill, Caitlin M. Reid, David Lyden, Crystal L. Mackall, Justin Evans, Leonard H. Wexler, Miki Kasai, Yorleny Vicioso
Publikováno v:
Cancer research. 76(6)
Metastatic tumors have been shown to establish microenvironments in distant tissues that are permissive to disseminated tumor cells. Hematopoietic cells contribute to this microenvironment, yet the precise initiating events responsible for establishi
Autor:
Steven A. Rosenberg, Constance M. Yuan, Marianna Sabatino, Terry J. Fry, Ling Zhang, Hua Zhang, Crystal L. Mackall, Rimas J. Orentas, Alan S. Wayne, Steven A. Feldman, Maryalice Stetler-Stevenson, James N. Kochenderfer, Dave Stroncek, Cindy Delbrook, Nick Tschernia, Nirali N. Shah, Seth M. Steinberg, Daniel W. Lee, Yongzhi K Cui
Publikováno v:
Lancet (London, England). 385(9967)
Summary Background Chimeric antigen receptor (CAR) modified T cells targeting CD19 have shown activity in case series of patients with acute and chronic lymphocytic leukaemia and B-cell lymphomas, but feasibility, toxicity, and response rates of cons