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pro vyhledávání: '"Melisa Vance"'
Autor:
Aravind Asokan, Telmo Llanga, Giridhar Murlidharan, Brian C. Gilger, Neil C Chungfat, Joanne Kurtzberg, R. Jude Samulski, William D. Bennett, Kenton T. Woodard, Matthew L. Hirsch, Melisa Vance
Publikováno v:
Scientific Reports
Although cord blood transplantation has significantly extended the lifespan of mucopolysaccharidosis type 1 (MPS1) patients, over 95% manifest cornea clouding with about 50% progressing to blindness. As corneal transplants are met with high rejection
Autor:
Melisa Vance, Joana S. Boura, Christopher D. Porada, Cláudia Lobato da Silva, Graça Almeida-Porada, Catarina Madeira, Weihong Yin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Mesenchymal stromal cells (MSC) constitutively express low levels of human leukocyte antigen-G (HLA-G), which has been shown to contribute to their immunomodulatory and anti-inflammatory properties. Here, we hypothesized that overexpression of HLA-G