Zobrazeno 1 - 10
of 685
pro vyhledávání: '"11"'
Autor:
Ke Li, Jia-Xing Wang, Nirmal K. Banda, Ang Li, Na Wang, Teng-Yue Diao, Dan Liu, Ning Ma, Jia-Yu Liu, Zongfang Li, Conrad A. Farrar, Rafael Bayarri-Olmos, Cui Qiang, Wuding Zhou, Xiao Yang, Li Xue, Weiju Wu, Peter Garred, Baojun Zhang, Kun-Yi Wu
Publikováno v:
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J X, Yang, X, Xue, L, Diao, T Y, Liu, J Y, Li, A, Zhang, B, Li, Z F, Farrar, C A, Banda, N K, Bayarri-Olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Objective: Collectin 11 (CL-11) is a soluble C-type lectin, a mediator of innate immunity. Its role in autoimmune disorders is unknown. We undertook this study to determine the role of CL-11 in a mouse model of rheumatoid arthritis (RA). Methods: A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea9e9ad849ed40dc058b9cf42746c85
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
Autor:
Louis M. Weiner, Bedilu Allo, Michael J. Pishvaian, Sara C. Sprague, Ivana Peran, Shahin Assefnia, Stephen S. Yoo, Eveline E. Vietsch, Michael B. Atkins, Kelly A. Martin, Anton Wellstein, Andrew A. Quong, Aimy Sebastian, Nicholas R. Hum, Gabriela G. Loots, Matthew McCoy, Stephen W. Byers, Sivanesan Dakshanamurthy, Anastasia Mavropoulos
Publikováno v:
Gastroenterology
Gastroenterology, vol 160, iss 4
Gastroenterology, vol 160, iss 4
BACKGROUND & AIMS: Pancreatic ductal adenocarcinomas (PDAC) are characterized by fibrosis and an abundance of cancer-associated fibroblasts (CAFs). We investigated strategies to disrupt interactions among CAFs, the immune system, and cancer cells, fo
Autor:
Hardy, RS, Fenton, C, Croft, AP, Naylor, AJ, Begum, R, Desanti, G, Buckley, CD, Lavery, G, Cooper, MS, Raza, K
Publikováno v:
Journal of Autoimmunity
Objective In rheumatoid arthritis, the enzyme 11 beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is highly expressed at sites of inflammation, where it converts inactive glucocorticoids (GC) to their active counterparts. In conditions of GC exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d89ee43216355dedf474d246904878a5
https://ora.ox.ac.uk/objects/uuid:4a4f9eee-29d7-43ac-bf1e-c516da321835
https://ora.ox.ac.uk/objects/uuid:4a4f9eee-29d7-43ac-bf1e-c516da321835
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1014-1019
Objective— We demonstrated that inflammatory cells and intima–media thickening are increased in carotids exposed to low-blood flow in the SJL/J (SJL) strain compared with other mouse strains. We hypothesized that the extent of inflammation associ
Autor:
Fan Kun Kong, Tatsuya Fukuiwa, Ken Ichiro Fukuchi, Hong Duck Kim, Robert Lalonde, J. Adam Maxwell, Kohtaro Fujihashi, Kazuki Tahara, De Chu C. Tang, Kent R. Van Kampen
Publikováno v:
The Journal of Gene Medicine. 9:88-98
One of the pathological hallmarks of Alzheimer's disease (AD) is deposits of amyloid beta-peptide (Abeta) in neuritic plaques and cerebral vessels. Immunization of AD mouse models with Abeta reduces Abeta deposits and improves memory and learning def
Publikováno v:
Inhal Toxicol
Previous in vitro and in vivo World Trade Center particulate matter (WTC(PM)) exposure studies have provided evidence of exposure-driven oxidative/nitrative stress and inflammation on respiratory tract and aortic tissues. What remains to be fully und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e962b80c6302bee0bd0bdd30389f71de
https://europepmc.org/articles/PMC9728549/
https://europepmc.org/articles/PMC9728549/
Autor:
Xiaolin Luo, Carolyn Hernandez, Shuangwei Li, Kaisa L. Hanley, Rohit Loomba, Nazilla Alderson, Helen He Zhu, Jia Fan, Gen-Sheng Feng, Nissi Varki, Rui Liao, Xufu Wei, Catherine Chu, Shuang-Jian Qiu, Kirsten N. Malo
Publikováno v:
Cell reports, vol 17, iss 11
The complexity of liver tumorigenesis is underscored by the recently observed anti-oncogenic effects of oncoproteins, although the mechanisms are unclear. Shp2/Ptpn11 is a proto-oncogene in hematopoietic cells, and antagonizes the effect of tumor sup
Autor:
Yu-Xiang Ye, Esther Lutgens, Zahi A. Fayad, Gerard Pasterkamp, Niels P. Riksen, Abraham J. P. Teunissen, Francois Fay, Matthias Nahrendorf, Joost Malkus, Ewelina Kluza, Leo A. B. Joosten, Raphaël Duivenvoorden, Marnix Lameijer, Mihai G. Netea, Roy van der Meel, Gregory R. Wojtkiewicz, Nils Rother, Thijs J. Beldman, Emma D. Klein, Brenda L. Sanchez-Gaytan, Carlos Pérez-Medina, Sheqouia A. Nauta, Mandy M. T. van Leent, Arjan Boltjes, Willem J. M. Mulder, Bowen Zhang, Bin Zhang, Filip K. Swirski, Yang Li, Siroon Bekkering, Yohana C. Toner, Xianxiao Zhou, Edward A. Fisher
Publikováno v:
Sci Transl Med
Science Translational Medicine, 13(584):eabe1433. American Association for the Advancement of Science (AAAS)
Science Translational Medicine, 13
Science Translational Medicine, 13, 584
Science translational medicine, 13(584):eabe1433. American Association for the Advancement of Science
Science Translational Medicine, 13(584):eabe1433. American Association for the Advancement of Science (AAAS)
Science Translational Medicine, 13
Science Translational Medicine, 13, 584
Science translational medicine, 13(584):eabe1433. American Association for the Advancement of Science
Macrophages play a central role in the pathogenesis of atherosclerosis. The inflammatory properties of these cells are dictated by their metabolism, of which the mechanistic target of rapamycin (mTOR) signaling pathway is a key regulator. Using myelo
Autor:
Angela Talusan, Sophia Kwon, Anna Nolan, Dean Ostrofsky, Yuyan Wang, Syed Hissam Haider, Erin J. Caraher, Rachel Lam, Mengling Liu, David J. Prezant, George Crowley
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 17
Issue 12
International Journal of Environmental Research and Public Health, Vol 17, Iss 4318, p 4318 (2020)
Volume 17
Issue 12
International Journal of Environmental Research and Public Health, Vol 17, Iss 4318, p 4318 (2020)
World Trade Center particulate matter (WTC-PM)-exposed firefighters with metabolic syndrome (MetSyn) have a higher risk of WTC lung injury (WTC-LI). Since macrophages are crucial innate pulmonary mediators, we investigated WTC-PM/lysophosphatidic aci
Autor:
Zhen Chen, Xingqi Wang, Shuang Peng, Yanhong Gu, Yang Sun, Lihong Shen, Yan Shen, Qiang Xu, Gen-Sheng Feng, Wenjie Guo, Wen Liu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Aberrant activation of NLRP3 inflammasome has an important function in the pathogenesis of various inflammatory diseases. Although many components and mediators of inflammasome activation have been identified, how NLRP3 inflammasome is regulated to p