Zobrazeno 1 - 10
of 232
pro vyhledávání: '"11"'
Autor:
Ke Li, Jia-Xing Wang, Nirmal K. Banda, Ang Li, Na Wang, Teng-Yue Diao, Dan Liu, Ning Ma, Jia-Yu Liu, Zongfang Li, Conrad A. Farrar, Rafael Bayarri-Olmos, Cui Qiang, Wuding Zhou, Xiao Yang, Li Xue, Weiju Wu, Peter Garred, Baojun Zhang, Kun-Yi Wu
Publikováno v:
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J X, Yang, X, Xue, L, Diao, T Y, Liu, J Y, Li, A, Zhang, B, Li, Z F, Farrar, C A, Banda, N K, Bayarri-Olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Objective: Collectin 11 (CL-11) is a soluble C-type lectin, a mediator of innate immunity. Its role in autoimmune disorders is unknown. We undertook this study to determine the role of CL-11 in a mouse model of rheumatoid arthritis (RA). Methods: A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea9e9ad849ed40dc058b9cf42746c85
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1014-1019
Objective— We demonstrated that inflammatory cells and intima–media thickening are increased in carotids exposed to low-blood flow in the SJL/J (SJL) strain compared with other mouse strains. We hypothesized that the extent of inflammation associ
Autor:
Jessica G. Borger, Benjamin G Dewals, Daniel M. Davis, Sheila Brown, Alexander T. Phythian-Adams, Annette M. Dougall, Adam N.R. Cartwright, Cecilia Johansson, Ruud H. P. Wilbers, Rachel J. Lundie, Peter C. Cook, Lucy H. Jackson-Jones, Franca Ronchese, Andrew S. MacDonald, Lauren M. Webb, Lisa M. Connor
Publikováno v:
The EMBO Journal 36 (2017) 16
Webb, L M, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A N R, Dougall, A M, Wilbers, R, Cook, P, Jackson-Jones, L, Phythian-Adams, A T, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', EMBO Journal . https://doi.org/10.15252/embj.201695345
The EMBO Journal, 36(16), 2404-2418
The EMBO Journal
Webb, L, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A, Dougall, A M, Wilbers, R H P, Cook, P, Jackson-Jones, L H, Phythian-Adams, A, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', The EMBO Journal, vol. 36, no. 16, pp. 2404-2418 . https://doi.org/10.15252/embj.201695345
Webb, L M, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A N R, Dougall, A M, Wilbers, R, Cook, P, Jackson-Jones, L, Phythian-Adams, A T, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', EMBO Journal . https://doi.org/10.15252/embj.201695345
The EMBO Journal, 36(16), 2404-2418
The EMBO Journal
Webb, L, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A, Dougall, A M, Wilbers, R H P, Cook, P, Jackson-Jones, L H, Phythian-Adams, A, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', The EMBO Journal, vol. 36, no. 16, pp. 2404-2418 . https://doi.org/10.15252/embj.201695345
Type 2 inflammation is a defining feature of infection with parasitic worms(helminths), as well as being responsible for widespread suffering in allergies.However, the precise mechanisms involved in T helper (Th) 2 polarization bydendritic cells (DCs
Autor:
Michael A. Brehm, Nomeda Girnius, Raymond M. Welsh, Norman J. Kennedy, Yvonne J. K. Edwards, Sonal Jangalwe, Varun N. Kapoor, Roger J. Davis, Jia Xu
Apoptosis of CD8 T cells is an essential mechanism that maintains immune system homeostasis, prevents autoimmunity, and reduces immunopathology. CD8 T cell death also occurs early during the response to both inflammation and costimulation blockade (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa7721cf2dbcb7276e8394e4fdd113e
https://europepmc.org/articles/PMC6344249/
https://europepmc.org/articles/PMC6344249/
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
Journal of Immunology, vol. 192, no. 1, pp. 200-205
Journal of Immunology, vol. 192, no. 1, pp. 200-205
Generating a diverse T cell memory population through vaccination is a promising strategy to overcome pathogen epitope variability and tolerance to tumor Ags. The effector and memory pool becomes broad in TCR diversity by recruiting high- and low-aff
Autor:
Luminita A. Stanciu, Sebastian L. Johnston, Onn Min Kon, Vasile Laza-Stanca, Patrick Mallia, Tatiana Kebadze, Simon D. Message, Nicholas Glanville, Nathan W. Bartlett, Alberto Papi, Hayley L. Parker, Ross P. Walton, Rebecca M. Pearson, Marco Contoli
Publikováno v:
Mucosal Immunology; Vol
Mucosal Immunology
Mucosal Immunology
Most asthma exacerbations are triggered by virus infections, the majority being caused by human rhinoviruses (RV). In mouse models, γδT cells have been previously demonstrated to influence allergen-driven airways hyper-reactivity (AHR) and can have
Autor:
Michelle Goritzka, Cecilia Johansson, Catherine Pereira, Lydia Durant, Spyridon Makris, Fiona J. Culley, Yutaro Kumagai, Shizuo Akira, Fahima Kausar, Matthias Mack
Publikováno v:
The Journal of Experimental Medicine
Goritzka et al. describe a role for recruited inflammatory monocytes in antiviral immunity and protection from RSV infection in mice. The authors demonstrate that this is critically dependent on the production of type I IFNs by alveolar macrophages t
Publikováno v:
Mucosal immunology. 6(2)
The role of T-helper type 17 (Th17) responses in airway remodeling in asthma is currently unknown. We demonstrate that both parenteral and mucosal allergen sensitization, followed by allergen inhalation, leads to Th17-biased lung immune responses. Un
Autor:
Jonathan Twynam-Perkins, Eugenio Cillan-Garcia, Thomas M. Wishart, Samantha L. Eaton, Anna Raper, Dominic Kurian, Scott Pirie, Anna E. Karagianni
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Karagianni, A, Eaton, S, Thekkedath Kurian, D, Cillan-Garcia, E, Twynam-Perkins, J, Raper, A, Wishart, T & Pirie, S 2021, ' Application across species of a one health approach to liquid sample handling for respiratory based-omics analysis ', Scientific Reports, vol. 11, no. 1, 14292 . https://doi.org/10.1038/s41598-021-93839-9
Scientific Reports
Karagianni, A, Eaton, S, Thekkedath Kurian, D, Cillan-Garcia, E, Twynam-Perkins, J, Raper, A, Wishart, T & Pirie, S 2021, ' Application across species of a one health approach to liquid sample handling for respiratory based-omics analysis ', Scientific Reports, vol. 11, no. 1, 14292 . https://doi.org/10.1038/s41598-021-93839-9
Airway inflammation is highly prevalent in horses, with the majority of non-infectious cases being defined as equine asthma. Currently, cytological analysis of airway derived samples is the principal method of assessing lower airway inflammation. Sam
Autor:
L. Nevi, Panagis Filippakopoulos, Raffaella Fittipaldi, Marco Segatto, Roberta Szokoll, Kamel Mamchaoui, Cinzia Bottino, Giuseppina Caretti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.6108. ⟨10.1038/s41467-020-19839-x⟩
Nature Communications, 2020, 11 (1), pp.6108. ⟨10.1038/s41467-020-19839-x⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.6108. ⟨10.1038/s41467-020-19839-x⟩
Nature Communications, 2020, 11 (1), pp.6108. ⟨10.1038/s41467-020-19839-x⟩
Duchenne muscular dystrophy (DMD) affects 1 in 3500 live male births. To date, there is no effective cure for DMD, and the identification of novel molecular targets involved in disease progression is important to design more effective treatments and