Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Su, Hao"'
Publikováno v:
Biochimica et biophysica acta. Molecular cell research, vol 1866, iss 3
Spatial and temporal subcellular localization plays critical roles in regulating protein function. Cten (C-terminal tensin like) is a member of the tensin family. Cten recruits signaling molecules, such as DLC1, to focal adhesions, modulates homeosta
DLC1 is a RhoGAP-containing tumor suppressor that inhibits angiogenesis by repressing VEGF production in epithelial cells. Here we report the roles of DLC1 in endothelial cells. Silencing of DLC1 (siDLC1) enhances cell migration but reduces tube form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a3a84147e21304c10395127a667bb4
https://escholarship.org/uc/item/7j11n9kk
https://escholarship.org/uc/item/7j11n9kk
Autor:
Su Hao Lo
Publikováno v:
The international journal of biochemistry & cell biology, vol 51, iss 1
C-terminal tensin-like (cten, also known as tensin4, TNS4) is a member of the tensin family. Cten protein, like the other three tensin family members, localizes to focal adhesion sites but only shares sequence homology with other tensins at its C-ter
Publikováno v:
Molecular Cancer Research. 10:34-39
Deleted in liver cancer 1 (DLC1) is a GTPase-activating protein (GAP) domain containing tumor suppressor that localizes to focal adhesions. In cancer cells, loss of DLC1 is known to enhance cancer cell migration. However, the role of DLC1 in normal c
Publikováno v:
Cancer Research. 70:8270-8275
The Rho GTPase-activating protein DLC1 is a tumor suppressor that is often deleted in liver cancer and downregulated in other cancers. DLC1 regulates the actin cytoskeleton, cell shape, adhesion, migration, and proliferation through its Rho GTPase-ac
Publikováno v:
Cancer Research. 68:7718-7722
Deleted in liver cancer-1 (DLC-1) is a RhoGTPase-activating protein (RhoGAP) domain containing tumor suppressor that is often down-regulated in various cancer types. Previously, we have shown that DLC-1 is recruited to focal adhesions by binding to t
Autor:
Yi Chun Liao, Su Hao Lo
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:843-847
Deleted in liver cancer 1 (DLC-1), as its name implied, was originally isolated as a potential tumor suppressor gene often deleted in hepatocellular carcinoma. Further studies have indicated that down-expression of DLC-1 either by genomic deletion or
Autor:
Russell A. Norris, Su Hao Lo, Diana Zelenika, Jorge Solis, Thierry Le Tourneau, Ronen Durst, Patrick T. Ellinor, Christian Dina, Serge Hercberg, Katelynn Toomer, Susan A. Slaugenhaupt, Nabila Bouatia-Naji, Elena Dolmatova, Albert Hagège, Richard Redon, Roger R. Markwald, Patrick Bruneval, Maelle Perrocheau, Jean-Jacques Schott, Francesca N. Delling, Florence Kyndt, Hervé Le Marec, Vincent Probst, Leticia Fernández-Friera, Philippe Pibarot, Philippe Froguel, Xavier Jeunemaitre, Robert A. Levine, Simon Lecointe, Nathan R. Tucker, Mark Lathrop, Fabrice Bonnet, Yohan Bossé, Ramachandran S. Vasan, Emelia J. Benjamin, Ming-Huei Chen, David J. Milan, Floriane Simonet, Ronan Roussel
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2015, 47 (10), pp.1206-1211. 〈10.1038/ng.3383〉
Nature Genetics, 2015, 47 (10), pp.1206-1211. ⟨10.1038/ng.3383⟩
Nature Genetics, Nature Publishing Group, 2015, 47 (10), pp.1206-1211. ⟨10.1038/ng.3383⟩
Nature genetics
Nature Genetics, Nature Publishing Group, 2015, 47 (10), pp.1206-1211. 〈10.1038/ng.3383〉
Nature Genetics, 2015, 47 (10), pp.1206-1211. ⟨10.1038/ng.3383⟩
Nature Genetics, Nature Publishing Group, 2015, 47 (10), pp.1206-1211. ⟨10.1038/ng.3383⟩
Nature genetics
International audience; Nonsyndromic mitral valve prolapse (MVP) is a common degenerative cardiac valvulopathy of unknown etiology that predisposes to mitral regurgitation, heart failure and sudden death. Previous family and pathophysiological studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7debf1a8c07e6f7457c181bc38c738e
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01191656/file/nihms711882.pdf
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01191656/file/nihms711882.pdf
Publikováno v:
Gene Expression. 13:179-189
We have adopted a special experimental strategy to identify early responsive genes during 12-O-tetradecanoylph-orbol-13-acetate (TPA)-induced macrophage-like differentiation of human myeloid leukemia cells (HL-60). This was performed in cells that we
Activation of EGF receptor (EGFR) triggers signaling pathways regulating various cellular events that contribute to tissue development and function. Aberrant activation of EGFR contributes to tumor progression as well as therapeutic resistance in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48e59306c4072c6dec6234f734b2028
https://europepmc.org/articles/PMC3745516/
https://europepmc.org/articles/PMC3745516/