Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Crystal L Mackall"'
Autor:
Stacey L. Berg, Kara L. Davis, Brenda J. Weigel, Charles G. Minard, Crystal L. Mackall, Elizabeth Fox, Rachel A. Kudgus, Stephan D. Voss, Melinda S. Merchant, Joel M. Reid, Xiaowei Liu
Publikováno v:
Lancet Oncol
Summary Background Immune checkpoint inhibitors targeting PD-1 have shown clinical benefit in adults with cancer, but data on these drugs in children are scarce. We did a phase 1–2 study of nivolumab, a PD-1 blocking monoclonal antibody, to determi
Autor:
Nirali N. Shah, Mark J. Roth, Haneen Shalabi, Amita Kulshreshtha, Constance M. Yuan, Dalia A. Salem, Crystal L. Mackall, Alina Dulau-Florea, Terry J. Fry, Maryalice Stetler-Stevenson, Armando C. Filie, Alan S. Wayne, Daniel W. Lee, Joanne Derdak, Bonnie Yates, Gaurav K. Gupta, Cindy Delbrook
Publikováno v:
Pediatr Blood Cancer
Background Accurate disease detection is integral to risk stratification in B-cell acute lymphoblastic leukemia (ALL). The gold standard used to evaluate response in the United States includes morphologic evaluation and minimal residual disease (MRD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c89c2d44636318636e59063161f9bd
https://europepmc.org/articles/PMC7036332/
https://europepmc.org/articles/PMC7036332/
Autor:
Adrienne H. Long, Rimas J. Orentas, Steven L. Highfill, Jillian P. Smith, Sneha Ramakrishna, Crystal L. Mackall, Alec J. Walker, Susana Galli, Rana El-Etriby, Maria Tsokos, Yongzhi Cui
Publikováno v:
Cancer Immunology Research. 4:869-880
Genetically engineered T cells expressing CD19-specific chimeric antigen receptors (CAR) have shown impressive activity against B-cell malignancies, and preliminary results suggest that T cells expressing a first-generation disialoganglioside (GD2)-s
Autor:
Eli Kane, Marie Claire Roderick, Staci Martin, Daniel W. Lee, Nirali N. Shah, Kari Struemph, Cindy Delbrook, Terry J. Fry, Crystal L. Mackall, Pamela L. Wolters, Haneen Shalabi, Mary Anne Toledo-Tamula, Bonnie Yates
Neurotoxicity associated with CAR-T cell therapy can be life-threatening. With rapid development of CAR-T therapies, a systematic method is needed to identify and monitor symptoms of neurotoxicity, elucidate potential etiologies, and compare toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddd097f65f1a686bb2854d871ecc08c
https://europepmc.org/articles/PMC6086728/
https://europepmc.org/articles/PMC6086728/
Autor:
Katherine K. Matthay, Crystal L. Mackall, Phillip Barnette, Richard B. Womer, Steven G. DuBois, Douglas S. Hawkins, Elizabeth Sinclair, Stephen L. Lessnick, Richard Gorlick, Katherine A. Janeway, Jeremy V. Edwards, Donald A. Barkauskas, Kieuhoa T. Vo, Holcombe E. Grier, C. Lorrie Epling, Mark Krailo, Elizabeth McIlvaine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 22, iss 14
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma. Experimental Design: Newly diagnose
Autor:
Crystal L. Mackall, Tolu Ariyo, Nirali N. Shah, David F. Stroncek, Terry J. Fry, Alan S. Wayne, Cindy Delbrook, David M. Loeb, Hahn Khuu, Mark Raffeld
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 22(12)
Relapse of hematologic malignancies is the primary cause of treatment failure after allogeneic hematopoietic stem cell transplantation (HCT). Treatment for post-HCT relapse using donor lymphocyte infusion (DLI) has limited utility, particularly in th
Autor:
Jiaqiang Ren, Hanh Khuu, Minh Tran, Crystal L. Mackall, Sue Ellen Frodigh, Melinda S. Merchant, David F. Stroncek, Daniel W. Lee, Marianna Sabatino
Background aims Autologous chimeric antigen receptor (CAR) T-cell therapies have shown promising clinical outcomes, but T-cell yields have been variable. CD19- and GD2-CAR T-cell manufacturing records were reviewed to identify sources of variability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c13f850306b0fc264f7e656225e291c
https://europepmc.org/articles/PMC4898642/
https://europepmc.org/articles/PMC4898642/
Autor:
Alan S. Wayne, Michael R. Bishop, Daniel H. Fowler, Kristin Baird, Seth M. Steinberg, Cynthia Delbrook, A. Rager, Crystal L. Mackall, Terry J. Fry, Jennifer L. Humphrey, Kelly Richards
Publikováno v:
Biology of Blood and Marrow Transplantation. 18(5):698-707
Some subsets of pediatric sarcoma patients have very poor survival rates. We sought to determine the feasibility and efficacy of allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric sarcoma populations with
Autor:
Bradford J. Wood, Donna Bernstein, Martha Amoako, Hua Zhang, Thomas A. Fleisher, Marianna Sabatino, Matthew Wright, Crystal L. Mackall, Seth M. Steinberg, Michel Morre, Dave Stroncek, Kristin Baird, Melinda S. Merchant, Aradhana M. Venkatasan
Publikováno v:
Clin Cancer Res
Purpose: Patients with metastatic or relapsed pediatric sarcomas receive cytotoxic regimens that induce high remission rates associated with profound lymphocyte depletion, but ultimately few survive long term. We administered adjuvant immunotherapy t
Publikováno v:
Pediatric Clinics of North America. 57:83-96
One major advance in T-cell-based immunotherapy in the last 20 years has been the molecular definition of numerous viral and tumor antigens. Adoptive T-cell transfer has shown definite clinical benefit in the prophylaxis and treatment of viral infect