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of 12 347
pro vyhledávání: ''
Autor:
Junjiao Yang, Yinghong Xiao, Peter V. Lidsky, Chien-Ting Wu, Luke R. Bonser, Shiming Peng, Miguel A. Garcia-Knight, Michel Tassetto, Chan-I Chung, Xiaoquan Li, Tsuguhisa Nakayama, Ivan T. Lee, Jayakar V. Nayak, Khadija Ghias, Kirsten L. Hargett, Brian K. Shoichet, David J. Erle, Peter K. Jackson, Raul Andino, Xiaokun Shu
Publikováno v:
Nat Microbiol
Nature microbiology, vol 8, iss 1
Nature microbiology, vol 8, iss 1
The coronavirus SARS-CoV-2 causes the severe disease COVID-19. SARS-CoV-2 infection is initiated by interaction of the viral spike protein and host receptor angiotensin-converting enzyme 2 (ACE2). We report an improved bright and reversible fluorogen
Autor:
Joicymara S. Xavier, Monika Moir, Houriiyah Tegally, Nikita Sitharam, Wasim Abdool Karim, James E. San, Joana Linhares, Eduan Wilkinson, David B. Ascher, Cheryl Baxter, Douglas E. V. Pires, Tulio de Oliveira
Publikováno v:
Nat Microbiol
The SARS-CoV-2 Africa dashboard is an interactive tool that enables visualization of SARS-CoV-2 genomic information in African countries. The customizable app allows users to visualize the number of sequences deposited in each country, and the varian
Autor:
Choudhary, Manish C, Chew, Kara W, Deo, Rinki, Flynn, James P, Regan, James, Crain, Charles R, Moser, Carlee, Hughes, Michael D, Ritz, Justin, Ribeiro, Ruy M, Ke, Ruian, Dragavon, Joan A, Javan, Arzhang Cyrus, Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L, Fletcher, Courtney V, Daar, Eric S, Wohl, David A, Eron, Joseph J, Currier, Judith S, Parikh, Urvi M, Sieg, Scott F, Perelson, Alan S, Coombs, Robert W, Smith, Davey M, Li, Jonathan Z, ACTIV-2/A5401 Study Team
Publikováno v:
Nature microbiology, vol 7, iss 11
Nat Microbiol
Nat Microbiol
SARS-CoV-2 mutations that cause resistance to monoclonal antibody (mAb) therapy have been reported. However, it remains unclear whether in vivo emergence of SARS-CoV-2 resistance mutations alters viral replication dynamics or therapeutic efficacy in
Autor:
Daniel F. Rojas-Tapias, Eric M. Brown, Emily R. Temple, Michelle A. Onyekaba, Ahmed M. T. Mohamed, Kellyanne Duncan, Melanie Schirmer, Rebecca L. Walker, Toufic Mayassi, Kerry A. Pierce, Julián Ávila-Pacheco, Clary B. Clish, Hera Vlamakis, Ramnik J. Xavier
Publikováno v:
Nat Microbiol
Colonization of the intestine by oral microbes has been linked to multiple diseases such as inflammatory bowel disease and colon cancer, yet mechanisms allowing expansion in this niche remain largely unknown. Veillonella parvula, an asaccharolytic, a
Autor:
Boeck, Lucas, Burbaud, Sophie, Skwark, Marcin, Pearson, Will H, Sangen, Jasper, Wuest, Andreas W, Marshall, Eleanor KP, Weimann, Aaron, Everall, Isobel, Bryant, Josephine M, Malhotra, Sony, Bannerman, Bridget P, Kierdorf, Katrin, Blundell, Tom L, Dionne, Marc S, Parkhill, Julian, Andres Floto, R
Publikováno v:
Nature Microbiology. 7:1431-1441
Funder: Wellcome Trust (Wellcome); doi: https://doi.org/10.13039/100004440
Funder: Cystic Fibrosis Trust (CF); doi: https://doi.org/10.13039/501100000292
Funder: Fondation Botnar; doi: https://doi.org/10.13039/501100011318
Funder: Euro
Funder: Cystic Fibrosis Trust (CF); doi: https://doi.org/10.13039/501100000292
Funder: Fondation Botnar; doi: https://doi.org/10.13039/501100011318
Funder: Euro
Autor:
Connor J. Beebout, Gabriella L. Robertson, Bradley I. Reinfeld, Alexandra M. Blee, Grace H. Morales, John R. Brannon, Walter J. Chazin, W. Kimryn Rathmell, Jeffrey C. Rathmell, Vivian Gama, Maria Hadjifrangiskou
Publikováno v:
Nat Microbiol
Urinary tract infections are among the most common human bacterial infections and place a significant burden on healthcare systems due to associated morbidity, cost, and antibiotic use. Despite being a facultative anaerobe, uropathogenic Escherichia
Autor:
Siva Sankari, Vignesh M. P. Babu, Ke Bian, Areej Alhhazmi, Mary C. Andorfer, Dante M. Avalos, Tyler A. Smith, Kwan Yoon, Catherine L. Drennan, Michael B. Yaffe, Sebastian Lourido, Graham C. Walker
Publikováno v:
Nat Microbiol
Symbiotic partnerships with rhizobial bacteria enable legumes to grow without nitrogen fertilizer because rhizobia convert atmospheric nitrogen gas into ammonia via nitrogenase. After Sinorhizobium meliloti penetrate the root nodules that they have e
Autor:
Adam J. Kanack, Antonios Bayas, Gemlyn George, Mouhamed Yazan Abou-Ismail, Bandana Singh, Mindy C. Kohlhagen, Noah P. Splinter, Monika Christ, Markus Naumann, Karen A. Moser, Kristi J. Smock, Alison Grazioli, Renren Wen, Demin Wang, David L. Murray, Anand Padmanabhan
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Background COVID-19 vaccines have been associated with a rare thrombotic and thrombocytopenic reaction, Vaccine-induced immune thrombotic thrombocytopenia (VITT) characterized by platelet-activating anti-PF4 antibodies. This study sought to assess cl
Autor:
Lifeng Xiong, Shifeng Wang, Joseph W. Dean, Kristen N. Oliff, Christian Jobin, Roy Curtiss, Liang Zhou
Publikováno v:
Nat Microbiol
Group 3 innate lymphoid cells (ILC3s) produce interleukin (IL)-22 and orchestrate with other cells in the gut, to mount productive host immunity against bacterial infection. However, the role of ILC3s in Salmonella enterica serovar Typhimurium (S. Ty
Autor:
Yuqing, Zhang, Rolf A, Brekken
Publikováno v:
J Leukoc Biol
Vascular endothelial growth factor-A (VEGF) is the predominant angiogenic factor that is expressed in solid tumors. Besides its critical function in mediating tumor angiogenesis, multiple studies have demonstrated that VEGF also contributes to tumor