Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Crystal L Mackall"'
Autor:
Johanna Theruvath, Marie Menard, Benjamin A. H. Smith, Miles H. Linde, Garry L. Coles, Guillermo Nicolas Dalton, Wei Wu, Louise Kiru, Alberto Delaidelli, Elena Sotillo, John L. Silberstein, Anna C. Geraghty, Allison Banuelos, Molly Thomas Radosevich, Shaurya Dhingra, Sabine Heitzeneder, Aidan Tousley, John Lattin, Peng Xu, Jing Huang, Nicole Nasholm, Andy He, Tracy C. Kuo, Emma R. B. Sangalang, Jaume Pons, Amira Barkal, Rachel E. Brewer, Kristopher D. Marjon, Jose G. Vilches-Moure, Payton L. Marshall, Ricardo Fernandes, Michelle Monje, Jennifer R. Cochran, Poul H. Sorensen, Heike E. Daldrup-Link, Irving L. Weissman, Julien Sage, Ravindra Majeti, Carolyn R. Bertozzi, William A. Weiss, Crystal L. Mackall, Robbie G. Majzner
Publikováno v:
Nature medicine, vol 28, iss 2
Nat Med
Nat Med
The disialoganglioside GD2 is overexpressed on several solid tumors, and monoclonal antibodies targeting GD2 have substantially improved outcomes for children with high-risk neuroblastoma. However, approximately 40% of patients with neuroblastoma sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aad3910b686c28eafa24813f728551c
https://escholarship.org/uc/item/5nz6n240
https://escholarship.org/uc/item/5nz6n240
Autor:
Lauren Little, Nirali N. Shah, Crystal L. Mackall, Haneen Shalabi, Daniel W. Lee, Seth M. Steinberg, John C. Molina, Bonnie Yates
Publikováno v:
Transplant Cell Ther
Hematopoietic stem cell transplantation (HSCT) may be used to consolidate chimeric antigen receptor (CAR) T cell therapy-induced remissions for patients with relapsed/refractory B cell acute lymphoblastic leukemia (B-ALL), but little is known about t
Autor:
Aidan Tousley, Sabine Heitzeneder, Johanna Theruvath, Robbie G. Majzner, Skyler P. Rietberg, Elena Sotillo, Volker Wiebking, Ronald D. Vale, Rui Dong, Rebecca Richards, Peng Xu, Evan W. Weber, Alexander R. Dunn, Rachel C. Lynn, Louai Labanieh, Vipul T. Vachharajani, Sang M. Nguyen, Meena Kadapakkam, Crystal L. Mackall, June Helen Myklebust
Publikováno v:
Cancer Discov
Cancer discovery, vol 10, iss 5
Cancer discovery, vol 10, iss 5
Insufficient reactivity against cells with low antigen density has emerged as an important cause of chimeric antigen receptor (CAR) T-cell resistance. Little is known about factors that modulate the threshold for antigen recognition. We demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37be618bc24a6cfd2084ac1ba61efbba
https://europepmc.org/articles/PMC7939454/
https://europepmc.org/articles/PMC7939454/
Autor:
Katherine K. Matthay, Crystal L. Mackall, Phillip Barnette, Richard B. Womer, Steven G. DuBois, Douglas S. Hawkins, Elizabeth Sinclair, Stephen L. Lessnick, Richard Gorlick, Katherine A. Janeway, Jeremy V. Edwards, Donald A. Barkauskas, Kieuhoa T. Vo, Holcombe E. Grier, C. Lorrie Epling, Mark Krailo, Elizabeth McIlvaine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 22, iss 14
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma. Experimental Design: Newly diagnose
Autor:
D. Williams Parsons, Paul S. Meltzer, Sharon E. Plon, Douglas S. Hawkins, Crystal L. Mackall, Steven G. DuBois, Lisa Mirabello, R. Lor Randall, Katherine A. Janeway, Poul H. Sorensen, Ching C. Lau, Rajen Mody, Malcolm A. Smith, Carol J. Bult, Pooja Hingorani, Sharon A. Savage, Javed Khan, Richard Gorlick, Stephen X. Skapek, Cigall Kadoch, Damon R. Reed, Peter C. Adamson, Philip J. Lupo, Marc Ladanyi, Jack F. Shern, Brian D. Crompton, Stephen L. Lessnick, Joshua D. Schiffman, Chand Khanna
Publikováno v:
Cancer genetics, vol 209, iss 5
Sarcomas are a rare subgroup of pediatric cancers comprised of a variety of bone and soft-tissue tumors. While significant advances have been made in improving outcomes of patients with localized pediatric sarcomas since the addition of systemic chem
Autor:
Terry J. Fry, Crystal L. Mackall
Publikováno v:
Hematology Am Soc Hematol Educ Program
Substantial progress has been made in the treatment of precursor B-cell acute lymphoblastic leukemia (B-ALL), but recurrent disease remains a leading cause of death in children due to cancer and outcomes for adults with B-ALL remain poor. Recently, c
Publikováno v:
Current Opinion in Pediatrics. 22:2-11
Most children with cancer can be cured with combination regimens of chemotherapy, radiation, surgery, or all. However, standard therapies are toxic to normal tissues, cancer cells commonly develop resistance to chemotherapy, and relapsed malignancy i
Publikováno v:
Expert Opinion on Biological Therapy. 10:163-178
Although most children with cancer are cured, there remain significant limitations of standard treatment, most notably chemotherapy resistance and non-specific toxicities. Novel immune-based therapies that target pediatric malignancies offer attracti
Autor:
Donna Bernstein, Lauren Long, Joanne Derdak, Crystal L. Mackall, Haven Battles, Lori Wiener, Patrick J. Mansky
Publikováno v:
Psycho-Oncology. 15:898-910
The long-term psychological impact of pediatric sarcoma is largely unknown. As part of a cross-sectional study examining the late effects of pediatric sarcoma therapy, we examined whether psychological distress or posttraumatic stress symptoms are pr
After decades of research, immunotherapies for cancer are demonstrating increasing success. These agents can amplify existent antitumour immunity or induce durable antitumour immune responses in a wide array of cancers. The spectrum of immunotherapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c0d5e93463d7ecaeef18ea0e534b21
https://europepmc.org/articles/PMC6953414/
https://europepmc.org/articles/PMC6953414/