Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chunai Gong"'
Autor:
Juanjuan Li, Chunai Gong, Xinlu Chen, Huanhuan Guo, Zongguang Tai, Nan Ding, Shen Gao, Yuan Gao
Publikováno v:
Journal of Nanobiotechnology. 21
Background Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of-care treatment of breast cancer. However, Dox therapy faces challenges such as hypoxia, acidosis, H2O2-rich conditions and condensed extracellular matrix in
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Enzalutamide (Enz) has shown limited bioavailability via oral administration. Castration-resistant prostate cancer (CRPC) is frequent among patients receiving 18–24 months of androgen deprivation therapy. The nonsteroidal anti-androgen e
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Background Biomimetic nanotechnology-based RNA interference (RNAi) has been successful in improving theranostic efficacy in malignant tumors. Its integration with hybrid biomimetic membranes made of natural cell membranes fused with liposomal membran
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Graphical Abstract In addition to early detection, early diagnosis, and early surgery, it is of great significance to use new strategies for the treatment of hepatocellular carcinoma (HCC). Studies showed that the combination of sorafenib (SFN) and t
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds great promise for effective suppression of tumor growth and invasion. In this study, a pH-responsive co-delivery platform was developed for metformin (Met), a know
Autor:
Chunai Gong, Yan Wu, Lu Han, Yujie Wang, Rong Wang, Xiaoyan Yu, Yongfang Yuan, Benming You, Shen Gao
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane
Autor:
Tai Zongguang, Yuan Gao, Jiyong Liu, Zheng Cai, Shen Gao, Guorui Li, Wenjun Jiang, Lei Qiang, Chunai Gong
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tumor site remain the main obstac
Autor:
Xin Wu, Xueying Ding, Chunai Gong, Guorui Li, Shen Gao, Zhuo Wang, Zhimin Han, Tian Jing, Lei Qiang, Yuan Gao, Yongfang Yuan
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipient cell types. We developed a strategy to isolate Exo e