Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zhijun Zhao"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Esophageal squamous cell carcinoma (ESCC) is a common malignant diagnosed cancer with increasing incidence rate and few treatment options. As a specific small-molecule inhibitor of the Wee1 tyrosine kinase, AZD1775 has previously shown potent antitum
Externí odkaz:
https://doaj.org/article/81762fed92e54b52b8cd7b9923ade8b0
Autor:
Yifan Song, Dong Fang, Chaojie Wang, Huishan Zeng, Songqiang Xie, Zhijun Zhao, Huiru Yang, Liang Chen
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Metastasis is one of most lethal causes that confer a poor prognosis of patients with esophageal squamous cell carcinoma (ESCC), whereas there is no available target drug for metastatic ESCC currently. In this study, we aimed to determine whether the
Autor:
Xiangchong Wang, Zhiyun Niu, Xuan Zhang, Gaohua Zhang, Zhijun Zhao, Lin Zhu, Jianping Zhang, Honglin Li, Yucong Xue, Pingping Chen
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 472:1457-1467
An increasing amount of evidence suggests that transmembrane member 16A (TMEM16A)-encoded Ca2+-activated Cl− channels play a crucial role in regulating tumorigenesis. Therefore, specific and potent TMEM16A inhibitors have been proposed to potential
Publikováno v:
Journal of Cellular and Molecular Medicine
Oesophageal squamous cell carcinoma (ESCC), the most common form of oesophageal malignancies in the Asia‐Pacific region, remains a major clinical challenge. In this study, we found that ivermectin, an effective antiparasitic drug that has been appr
Publikováno v:
DNA and cell biology. 40(10)
Breast invasive carcinoma (BRCA) is becoming the most common malignant disease worldwide, and there is intense interest in identifying diagnostic biomarkers that can be targeted for treatment of BRCA. Recent evidence has shown that calcyclin binding
Autor:
Pingping Chen, Jie Jia, Jianfeng Yi, Gaohua Zhang, Yanshuang Liu, Zhijun Zhao, Xuan Zhang, Yuanyuan Wang, Ruilian Xiu
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1868(12)
Anoctamin-1 (ANO1), also known as transmembrane protein 16A (TMEM16A), is identified as a Ca2+-activated Cl− channel that is expressed in many organs and tissues. It is involved in numerous major physiological functions and especially in tumor grow
Publikováno v:
SSRN Electronic Journal.
Anoctamin-1 (ANO1), also known as transmembrane protein 16A (TMEM16A), is identified as a Ca2+-activated Cl− channel that is expressed in many organs and tissues. It is involved in numerous major physiological functions and especially in tumor grow
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Sirtuin1 (SIRT1), one of NAD(+)-dependent protein deacetylases, is proved to be neuroprotective in aging diseases, but its effect on neuronal apoptosis has not been clarified. To investigate the role of SIRT1 in inhibiting neuronal apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93534b285feaa0d22407123c3ed9162c
https://europepmc.org/articles/PMC7704980/
https://europepmc.org/articles/PMC7704980/
Publikováno v:
Pharmacological research. 156
Transmembrane member 16A (TMEM16A) encoded Ca
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
Esophageal squamous cell carcinoma (ESCC) is a common malignant diagnosed cancer with increasing incidence rate and few treatment options. As a specific small-molecule inhibitor of the Wee1 tyrosine kinase, AZD1775 has previously shown potent antitum