Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xiawei Wei"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Myeloid-derived suppressor cells (MDSCs) are one of the major components of the tumor microenvironment. Evidence has shown differences in the functions and fates of MDSCs in the tumor tissue and the periphery. However, the exact mechanism that regula
Externí odkaz:
https://doaj.org/article/732452dd28b94d758094778c94f2c76b
Autor:
Xiawei Wei, An Tong, Yang Yang, Ruyu Pi, Xia Zhao, Tianqi Lu, Xiaoyi Hu, Houhui Shi, Hongyi Li, Yuquan Wei, Xi Wang, Yu Liu
Publikováno v:
Cancer Letters. 523:72-81
Mechanistic target of rapamycin (mTOR) forms two distinct complexes, mTOR complex 1 (mTORC1) and mTORC2. Here we investigated the antitumor effect of dual mTORC1/2 inhibitor AZD2014 on epithelial ovarian cancer (EOC) and its potential effect on immun
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-12 (2021)
Molecular Biomedicine
Molecular Biomedicine
Acute liver injury is a common but urgent clinical condition, and its underlying mechanism remains to be further elucidated. Concanavalin A (ConA)-induced liver injury was investigated in the study. Different from the caspase-dependent cell apoptosis
Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin
Autor:
Yuan Cheng, Xuejiao Han, Qingfang Li, Fei Mo, Xiawei Wei, Yuquan Wei, Houhui Shi, Siyuan Chen
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer
Molecular Cancer
Background Drug-resistance and severe side effects of chemotherapeutic agents result in unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role in progression of cancer including lung cancer. However, the specific
Autor:
Xin He, Fan Tang, Chongqi Tu, Yi Luo, Xiawei Wei, Jingyun Yang, Yong Zhou, Li Min, Houhui Shi, Siyuan Chen, Yan Tie, Weiqi Hong
Publikováno v:
Annals of Surgical Oncology. 28:6453-6463
Tenosynovial giant cell tumor (TGCT) is a locally aggressive tumor with colony-stimulating factor 1 receptor (CSF1R) signal expression. However, there is a lack of better in vivo and ex vivo models for TGCT. This study aims to establish a favorable p
Autor:
Meimei Xiong, Meijuan Huang, Yong Wang, Maling Gou, Shuai Wang, Ling Yang, Tianyi Kang, Jiao Zhu, Jinlu Liu, Yang Li, Yulan Huang, Xiawei Wei
Publikováno v:
ACS Applied Materials & Interfaces. 11:36371-36382
Combination of chemotherapeutics and immunomodulators can generate synergistic anticancer efficacy, exerting efficient chemoimmunotherapy for cancer treatment. Nanoparticulate delivery systems hold great promise to promote synergistic anticancer effi
Autor:
Wei Wang, Xuemei He, Canhua Huang, Hongxin Deng, Yu Liu, Cai He, Zhenfei Bi, Jingyun Yang, Xiawei Wei, Lunzhi Dai, Tianqi Lu, Xiangyu Pan, Hong Lei, Weiqi Hong
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Mesenchymal stem cell (MSC)-mediated immunomodulation has been harnessed for the treatment of human diseases, but its underlying mechanism has not been fully understood. Dead cells, including apoptotic cells have immunomodulatory properties. It has b
Autor:
Edouard C. Nice, Li Zhou, Wei Gao, Changlong Li, Yujia He, Junhong Han, Yunlong Lei, Zhe Zhang, Lu Zhang, Hai-Ning Chen, Xiawei Wei, Canhua Huang, Siyuan Qin, Zong-Guang Zhou, Jiayang Liu, Yan Chen
Publikováno v:
Theranostics
Rationale: The sustained and severe endoplasmic reticulum (ER) stress in cancer cells may contribute to apoptotic cell death, thus representing a potential target for cancer therapy. Brigatinib is an anaplastic lymphoma kinase (ALK) inhibitor approve
Publikováno v:
Nano Letters. 19:2905-2913
Multidrug resistance (MDR) is still a formidable obstacle for the majority of anticancer drugs during chemotherapy. MDR is generally divided into the pump and nonpump resistances, which significantly and simultaneously reduce drug accumulation and po
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-27 (2019)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Carbon nanomaterials are a growing family of materials featuring unique physicochemical properties, and their widespread application is accompanied by increasing human exposure. Main body Considerable efforts have been made to characterize