Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ulf R, Rapp"'
Autor:
Friedrich Grimminger, Baktybek Kojonazarov, Samantha Storn, Werner Seeger, Stefan Gattenlöhner, Ralph T. Schermuly, Rajkumar Savai, Soni Savai Pullamsetti, Andreas Weigert, Ulf R. Rapp, Nefertiti El-Nikhely, Ludger Fink, Gabriele A. Krombach, Henning Gall, Janine Wolf, Hossein Ardeschir Ghofrani, Ylia Salazar
Publikováno v:
Science Translational Medicine. 9
Dyspnea is a frequent, devastating, and poorly understood symptom of advanced lung cancer. In our cohort, among 519 patients who underwent a computed tomography scan for the diagnosis of lung cancer, 250 had a mean pulmonary artery diameter of >28 mm
Autor:
Ulf R. Rapp, Tripat Kaur Oberoi-Khanuja, Krishnaraj Rajalingam, Christiaan Karreman, Sarit Larisch
Publikováno v:
Journal of Biological Chemistry. 287:28445-28455
Inhibitor of apoptosis (IAPs) proteins are characterized by the presence of evolutionarily conserved baculoviral inhibitor of apoptosis repeat (BIR) domains, predominantly known for their role in inhibiting caspases and, thereby, apoptosis. We have s
Publikováno v:
Advances in Enzyme Regulation. 50:147-159
Autor:
Esther Asan, Semra Ceteci, Christiaan Karreman, Fatih Ceteci, Boris W Kramer, Rudolf Götz, Ulf R. Rapp
Publikováno v:
Cancer Cell. 12:145-159
SummaryProgression of non-small-cell lung cancer (NSCLC) to metastasis is poorly understood. Two genetic approaches were used to evaluate the role of adherens junctions in a C-RAF driven mouse model for NSCLC: conditional ablation of the cdh1 gene an
Autor:
Izabella T Silva, Annelise Carvalho, Karen L Lang, Sabine E Dudek, Dörthe Masemann, Fernando J Durán, Miguel S B Caro, Ulf R Rapp, Viktor Wixler, Eloir P Schenkel, Cláudia M O Simões, Stephan Ludwig
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)
Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer showing high resistance to radiation and chemotherapy. Despite the outstanding progress made i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2beac715ec4a967bce3606af0dbc441d
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117794
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117794
Autor:
Ulf R. Rapp, Jakob Troppmair
Publikováno v:
Biochemical Pharmacology. 66:1341-1345
Research of the last years has demonstrated the absolute requirement of mitogenic signaling pathways for the control of cell survival. As reviewed here for the members of the Raf kinase family, apoptosis suppression proceeds through diverse mechanism
Autor:
Rolf Müller, Tatjana V. Achenbach, Quek Choon Lau, Thomas Stübig, Emily P. Slater, Ulf R. Rapp
Publikováno v:
International Journal of Cancer. 104:425-432
The Raf serine-threonine kinase is upregulated in many human tumors and plays a pivotal role in tumor cell proliferation and survival. Abrogation of c-Raf expression by specific antisense oligonucleotides (Raf-AS-ODN) efficiently blocks tumor cell gr
Autor:
Izabella T, Silva, Annelise, Carvalho, Karen L, Lang, Sabine E, Dudek, Dörthe, Masemann, Fernando J, Durán, Miguel S B, Caro, Ulf R, Rapp, Viktor, Wixler, Eloir P, Schenkel, Cláudia M O, Simões, Stephan, Ludwig
Publikováno v:
PLoS ONE
Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer showing high resistance to radiation and chemotherapy. Despite the outstanding progress made i
Autor:
Michael Sendtner, Ludmilla Wixler, Jakob Troppmair, Ulf R. Rapp, Veronique LeMellay, Dragomir Dinev, Bruce W.M. Jordan, Stephan Ludwig, Rudolf Götz
Publikováno v:
Journal of Biological Chemistry. 276:39985-39989
The inhibitor of apoptosis proteins (IAPs) have been shown to interact with a growing number of intracellular proteins and pathways to fulfil their anti-apoptotic role. In the search for novel IAP-interacting proteins we identified the neurotrophin r
Publikováno v:
Oncogene. 20:4807-4816
Bcl-2 family proteins play a critical role in the regulation of cell survival by controlling the activation of the cell death executing caspase machinery. Recent work demonstrated that they also provide a link between growth factor signaling and cell