Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Razq Hakem"'
Autor:
Neil MacLean, Shawn Brennan, Adam C. Smith, Rose Hurren, Allison Berger, Xiaoming Wang, Razq Hakem, Marcela Gronda, Mark D. Minden, Sara Farshchi Zarabi, Simon Kavanagh, Tary Traore, G. Wei Xu, Aaron D. Schimmer, Emil F. Pai, Samir H. Barghout, Ondrej Halgas, Michael Milhollen, Marc L. Hyer, Parasvi S. Patel, Danny V. Jeyaraju
Publikováno v:
Leukemia. 33:37-51
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy for which new therapeutic approaches are required. One such potential therapeutic strategy is to target the ubiquitin-like modifier-activating enzyme 1 (UBA1), the initiating enzyme
Autor:
Jennifer L. Gommerman, Dania Haddad, Ahmad Zaheen, Olga L. Rojas, Bryant Boulianne, Alberto Martin, Razq Hakem, Thanh Nguyen, Anat Kapelnikov, Conglei Li
Publikováno v:
The Journal of Immunology. 191:5840-5847
Germinal centers (GCs) are clusters of activated B cells that form in secondary lymphoid organs during a T-dependent immune response. B cells enter GCs and become rapidly proliferating centroblasts that express the enzyme activation-induced deaminase
Autor:
Philipp J. Jost, Thomas Kaufmann, Andreas Strasser, Raffi Gugasyan, Tak W. Mak, Marc Pellegrini, Philippe Bouillet, Mark J. Smyth, Vishva M. Dixit, John Silke, Hamsa Puthalakath, Erika Cretney, Steve Gerondakis, Razq Hakem
Publikováno v:
Immunity
Apoptotic death of hepatocytes, a contributor to many chronic and acute liver diseases, can be a consequence of overactivation of the immune system and is often mediated by TNFalpha. Injection with lipopolysaccharide (LPS) plus the transcriptional in