Zobrazeno 1 - 10
of 25
pro vyhledávání: '"ZHAO LI"'
Autor:
Aie Xu, Yangyang Ma, Mengyan Zhu, Jiaqi Wang, Wenzhong Yu, Yongping Xu, Xiaoyan Zhang, Ping Wang, Yong Li, Zhao Li
Publikováno v:
Journal of Investigative Dermatology. 141:374-384
Ubiquitin-conjugating enzyme E2S (UBE2S) is involved in protein degradation and signal transduction, but its function in the development of melanoma is unclear. We focused on the role of UBE2S in melanoma development both in vitro and in vivo. UBE2S
Autor:
Chuanyong Liu, Yuntao Ma, Runze Xu, Guanyu Chen, Honghui Zeng, Jianbo Liu, Bing Xue, Zhao Li, Xinyun Li
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 11, Pp 1-15 (2021)
Cell Death and Disease, Vol 12, Iss 11, Pp 1-15 (2021)
Chemotherapy-induced intestinal mucositis (CIM) is a common adverse reaction to antineoplastic treatment with few appropriate, specific interventions. We aimed to identify the role of the G protein coupled estrogen receptor (GPER) in CIM and its mech
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
RationaleDisruption of intracellular calcium (Ca2+) homeostasis is implicated in inflammatory responses. Here we investigated endoplasmic reticulum (ER) Ca2+ efflux through the Inositol 1,4,5-trisphosphate receptor (IP3R) as a potential mechanism of
Autor:
Xuemei Deng, Yong-Xing He, Weifan Jiang, Tao Shi, Zhen Wang, Hanzhong Feng, Dan Liu, Honghua Zhang, Yingmei Lu, Yiyue Feng, Jian Zhang, Junfang Li, Zhao Li
Publikováno v:
European journal of medicinal chemistry. 227
Although gastric cancer has become a major public health problem, oral agents applied in clinics for gastric cancer therapy are scarce. Therefore, to explore new oral chemical entities with high efficiency and low toxicity, 41 o-aminobenzamide deriva
Publikováno v:
Oncology Reports
Bone marrow‑derived mesenchymal stem cells (MSCs), are the basic cellular components that make up the bone marrow microenvironment (BMM). In acute myeloid leukemia (AML), the morphology and function of MSCs changes in accordance with the transforma
Publikováno v:
Archives of Oral Biology. 99:183-189
Objective Oral lichen planus (OLP) is a chronic inflammatory mucosal lesion and systemic disease. In OLP, reticular type is the most common presentation of the disease. However, little is known about it. The aim of this study was to analyze the path
Publikováno v:
Pancreas. 47:1040-1049
OBJECTIVE The aim of the study was to investigate the biochemical and functional properties of a rat acellular pancreatic bioscaffolds (APBs). METHODS Fresh pancreata from 10 rats were soaked and perfused through portal veins using Easy-Load Digital
Autor:
Zhi Xing Fan, Jia Wang Ding, Di Liu, Yun Zhao Li, Jian Yang, Jing Zhang, Gang Zhou, Hui Wu, Jun Yang, Xin-An Wang
Publikováno v:
Nutrition, metabolism, and cardiovascular diseases : NMCD. 31(6)
Background and aims Myocardial ischemia/reperfusion injury (MI/RI) is a result of coronary revascularization, and often increases cell apoptosis and autophagy. Downregulated cellular FADD-like-IL-1β-converting enzyme-inhibitory protein (cFLIP) was a
Autor:
Yiyue Feng, Xiaoling Hu, Tao Shi, Zhen Wang, Zhao Li, Honghua Zhang, Weifan Jiang, Junfang Li, Yingmei Lu
Publikováno v:
European Journal of Medicinal Chemistry. 227:113908
Highly efficacious and tolerable agents for the treatment of glioblastoma (GBM), the most common and aggressive primary brain tumor, are urgently needed. Herein, we reveal the design, synthesis and biological evaluation of several piperazine based be
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1174
Previous research has demonstrated that Herba Lysimachiae (HL) exerts the dual effects on platelet aggregation in the synovium, which may contribute to its protection against synovial lesions under different situations. However, the mechanism is uncl