Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Razq Hakem"'
Autor:
Paul R Lakin, Mary Speir, Heather Patsiouras, Ben A. Croker, Roman Othmar Braun, Shu Wang, Rowena S. Lewis, Razq Hakem, Akshay A. D’Cruz, Nathan E. Lewis, Andrew W. Roberts, Kate E. Lawlor, Anca I. Stoica, Louise H. Cengia, Isaac Shamie, Joanne A. O’Donnell, Edie Weller, Inbar Shlomovitz, Motti Gerlic, Meghan Bliss-Moreau, Jeffrey J. Babon, Lorraine A. O'Reilly, Alyce A. Chen, Cameron J. Nowell, Michelle A. Kelliher
Publikováno v:
Nature immunology
Ptpn6 is a cytoplasmic phosphatase that functions to prevent autoimmune and interleukin-1 (IL-1) receptor-dependent, caspase-1-independent inflammatory disease. Conditional deletion of Ptpn6 in neutrophils (Ptpn6∆PMN) is sufficient to initiate IL-1
Autor:
Mathilde Gavillet, Shu Wang, Ben A. Croker, David A. Williams, Michelle A. Kelliher, Meghan Bliss-Moreau, Sylvia Dietrich, Manolis Pasparakis, Alyce A. Chen, Akshay A. D’Cruz, Mary Speir, James E Vince, Arshed Al-Obeidi, Kate E. Lawlor, Maria Ericsson, Razq Hakem
Publikováno v:
Science signaling. 11(546)
Neutrophil extracellular trap (NET) formation can generate short-term, functional anucleate cytoplasts and trigger loss of cell viability. We demonstrated that the necroptotic cell death effector mixed lineage kinase domain–like (MLKL) translocated