Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hans M.G. Princen"'
Autor:
Patrick C.N. Rensen, Geurt Stokman, Hans M.G. Princen, Michael Feigh, Marta Iruarrizaga-Lejarreta, José W.A. van der Hoorn, Ditte Denker Thorbekk, John J.P. Kastelein, Sanne Skovgård Veidal, Elsbet J. Pieterman, Lars Verschuren, David A. Fraser, Cristina Alonso, Scott L. Friedman, Brittany Basta, Tore Skjaeret, Anita M. van den Hoek, Jimmy F.P. Berbée
Publikováno v:
Liver International
Liver International, 40(11), 2860-2876. WILEY
Liver International, 40(11), 2860-2876. WILEY
Background & Aims While fibrosis stage predicts liver‐associated mortality, cardiovascular disease (CVD) is still the major overall cause of mortality in patients with NASH. Novel NASH drugs should thus ideally reduce both liver fibrosis and CVD. I
Autor:
Marcus Henricsson, Ralf Nilsson, Anders Cavallin, V. Sashi Gopaul, Eva Hurt-Camejo, Hans M.G. Princen, Linnéa Bergenholm, Steven E. Nissen, Rahul Agrawal, Annica Jarke, Elsbet J. Pieterman
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
We investigated the effects of chronic oral administration of mineral oil, versus corn oil as control, on intestinal permeability, inflammatory markers, and plasma lipids in APOE*3-Leiden.CETP mice. Mice received mineral oil or corn oil 15 or 30 μL/
Autor:
Margareta Behrendt, Arianne van Koppen, Suvi E. Heinonen, Ann-Cathrine Jönsson-Rylander, Anne-Christine Andréasson, Aswin L. Menke, Hans M.G. Princen, Brendan Leighton, Marianne G. Pouwer, Anita M. van den Hoek, J. Wouter Jukema, Elsbet J. Pieterman
Publikováno v:
Journal of Diabetes Research. 2019:1-13
Background. There is a lack of predictive preclinical animal models combining atherosclerosis and type 2 diabetes. APOE∗3-Leiden (E3L) mice are a well-established model for diet-induced hyperlipidemia and atherosclerosis, and glucokinase+/− (GK+/
Autor:
Tsai-Sang Dederichs, Peter Kohl, Katja Krebs, Clinton S. Robbins, Dennis Wolf, Bianca Dufner, Jiadai Zou, E.J. Pieterman, Timo Heidt, Christopher Starz, Rafael Kaeser, Natalie Hoppe, Peter Stachon, Tobias Boettler, Carmen Härdtner, Benoît Ho-Tin-Noé, Hans M.G. Princen, Florian Willecke, Andreas Zirlik, Diana Sharipova, Carolin A. Ehlert, Filip K. Swirski, Constantin von zur Mühlen, Alina Jander, Ingo Hilgendorf, Christoph Bode, Josef Madl, Simon Rauterberg, Jan Kornemann
Publikováno v:
Basic Research in Cardiology
Statins induce plaque regression characterized by reduced macrophage content in humans, but the underlying mechanisms remain speculative. Studying the translational APOE*3-Leiden.CETP mouse model with a humanized lipoprotein metabolism, we find that
Autor:
G. Stokman, M. Oudshoorn-Dickmann, Astrid Valles-Sanchez, C. Vendrell Tornero, Hans M.G. Princen, M. Golinska, N. Keijzer, M. De Haan, M. Van Veen, H. Wattimury, K. Van Rooijen, V. Zancanella, Ying Poi Liu
Publikováno v:
Web of Science
Autor:
Lars Verschuren, Nicole Worms, Martien P. M. Caspers, Aswin L. Menke, Anita M. van den Hoek, Hans M.G. Princen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Non-alcoholic steatohepatitis (NASH) is the most rapidly growing liver disease that is nevertheless without approved pharmacological treatment. Despite great effort in developing novel NASH therapeutics, many have failed in clinical trials. This has
Autor:
Bianca Dufner, Dennis Wolf, Ingo Hilgendorf, Jan Kornemann, Natalie Hoppe, Peter Stachon, Andreas Zirlik, Hans M.G. Princen, C. Haerdtner, C. Bode, Katja Krebs
Publikováno v:
European Heart Journal. 40
Background Guidelines recommend cholesterol lowering for primary and secondary prevention of cardiovascular disease. While lipid lowering has been reported to induce plaque regression, the underlying mechanisms have remained speculative. Purpose We h
Autor:
A.E. Kozijn, Reinout Stoop, Yvonne van Gemert, N. Kruisbergen, Peter L E M van Lent, Harrie Weinans, Martijn H J van den Bosch, E.J. Pieterman, Arjen B. Blom, Marianne G. Pouwer, Hans M.G. Princen
Publikováno v:
Cartilage, synovium and bone.
Background High systemic cholesterol levels have been associated with osteoarthritis (OA) development and lowering cholesterol using statins has been suggested as a potential treatment for OA1. Recently, novel therapeutic high-intensive cholesterol-l
Autor:
Hans M.G. Princen, R. Kleemann, A.E. Kozijn, Susan Kühnast, Simon C. Mastbergen, F.P.J.G. Lafeber, Harrie Weinans, Reinout Stoop, Lobke Gierman, E.J. Pieterman, R.A. van der Heijden, F. van der Ham, Anne-Marie Zuurmond, A.M. van den Hoek, Martine C. Morrison, A. Van Koppen, I. Bobeldijk, P.M. Stavro, Petra Mulder
Publikováno v:
Osteoarthritis and Cartilage, 26(1), 95. W.B. Saunders Ltd
Osteoarthritis and cartilage, 26(1), 95-107. ELSEVIER SCI LTD
Osteoarthritis and Cartilage, 1, 25, 95-107
Osteoarthritis and cartilage, 26(1), 95-107. ELSEVIER SCI LTD
Osteoarthritis and Cartilage, 1, 25, 95-107
Objective: Human cohort studies have demonstrated a role for systemic metabolic dysfunction in osteoarthritis (OA) pathogenesis in obese patients. To explore the mechanisms underlying this metabolic phenotype of OA, we examined cartilage degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b65a74b2fe861890953043093838cf6
https://dspace.library.uu.nl/handle/1874/363420
https://dspace.library.uu.nl/handle/1874/363420
Publikováno v:
Atherosclerosis Supplements. 32:8-9