Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Onno W. Akkerman"'
Autor:
Reihaneh Abolhassani-Chimeh, Onno W. Akkerman, Antonia M. I. Saktiawati, Nieko C. Punt, Mathieu S. Bolhuis, Yanri W. Subronto, null Sumardi, Tjip S. van der Werf, Jos G. W. Kosterink, Jan-Willem C. Alffenaar, Marieke G. G. Sturkenboom
Publikováno v:
Antimicrobial Agents and Chemotherapy, 66(7). AMER SOC MICROBIOLOGY
Antimicrob Agents Chemother
Antimicrob Agents Chemother
Pyrazinamide is one of the first-line antituberculosis drugs. The efficacy of pyrazinamide is associated with the ratio of 24-h area under the concentration–time curve (AUC(24)) to MIC. The objective of this study was to develop and validate a limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1126546cd7b6e5cf72651f668cf3980
https://research.rug.nl/en/publications/1c4601e3-d753-4844-9dc2-9bb3ae8df6f7
https://research.rug.nl/en/publications/1c4601e3-d753-4844-9dc2-9bb3ae8df6f7
Autor:
Tjip S. van der Werf, Dick van Soolingen, Marieke G G Sturkenboom, Onno W. Akkerman, Richard M. Anthony, Wiel C M de Lange, Mathieu S. Bolhuis, Vanessa B Vogensen, Huib A. M. Kerstjens, Jan-Willem C. Alffenaar
Publikováno v:
Antimicrobial Agents and Chemotherapy, 66(2):e01829-21. AMER SOC MICROBIOLOGY
Antimicrob Agents Chemother
Antimicrob Agents Chemother
Moxifloxacin is an attractive drug for the treatment of isoniazid-resistant rifampicin-susceptible tuberculosis (TB) or drug-susceptible TB complicated by isoniazid intolerance. However, co-administration with rifampicin decreases moxifloxacin exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a9f9ff8a8cc9d29e04b52704049c4b
https://research.rug.nl/en/publications/19364a90-b913-4be9-a073-401e4b3a043b
https://research.rug.nl/en/publications/19364a90-b913-4be9-a073-401e4b3a043b
Autor:
Onno W. Akkerman, Simon Tiberi, Hannah Yejin Kim, Giovanni Battista Migliori, Jan-Willem C. Alffenaar
Publikováno v:
International Journal of Infectious Diseases, Vol 92, Iss, Pp S5-S9 (2020)
International Journal of Infectious Diseases, 92, S5-S9. ELSEVIER SCI LTD
International Journal of Infectious Diseases, 92, S5-S9. ELSEVIER SCI LTD
Therapeutic Drug Monitoring (TDM) is increasingly recommended to ensure the correct drug dose thereby minimizing adverse events and maximizing regimen efficacy. To facilitate implementation in TB programs, a framework for TDM is urgently needed. TDM
Autor:
Jan-Willem C. Alffenaar, Ivan S. Pradipta, Natasha van't Boveneind-Vrubleuskaya, Onno W. Akkerman, Eelko Hak
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 8, Iss 1, Pp 1-12 (2019)
Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control, 8:115. BioMed Central Ltd.
Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control, 8:115. BioMed Central Ltd.
Background Since in low incidence TB countries population migration and complex treatment of drug-resistant tuberculosis (DR-TB) patients are major issues, we aimed to analyse patient risk factors associated with the incidence of poor outcome of TB t
Publikováno v:
International Journal of Tuberculosis and Lung Disease, 25(6), 419-420. International Union against Tubercul. and Lung Dis.
The International Journal of Tuberculosis and Lung Disease
The International Journal of Tuberculosis and Lung Disease
SUMMARY BACKGROUND: There are no data comparing the 6–9 month oral three-drug Nix regimen (bedaquiline, pretomanid and linezolid [BPaL]) to conventional regimens containing bedaquiline (B, BDQ) and linezolid (L, LZD). METHODS: Six-month post end-of
Autor:
Onno W. Akkerman, Mireille A. Wessels, Samiksha Ghimire, Daan J Touw, Jan-Willem C. Alffenaar, Erwin M Jongedijk, Simone H J van den Elsen, Mathieu S. Bolhuis, Tjip S. van der Werf
Publikováno v:
European Respiratory Journal, 56(4):2000803. EUROPEAN RESPIRATORY SOC JOURNALS LTD
The persisting worldwide burden of tuberculosis (TB) is worrisome. In 2018, an estimated 10 million individuals developed TB and 1.45 million deceased [1]. The increase in drug resistance is an important point of concern. Resistance can be acquired b
Autor:
J F M van Boven, Fajri Gafar, Ivan S. Pradipta, Onno W. Akkerman, J-W C Alffenaar, Eelko Hak, R A Chimeh
Publikováno v:
International Journal of Tuberculosis and Lung Disease, 24(8), 811-819. International Union against Tubercul. and Lung Dis.
BACKGROUND: Despite considerable efforts to globally eradicate TB, and the availability of effective antibiotics, TB elimination goals are falling behind. While non-adherence to TB drug regimens may compromise effective treatment, its full impact is
Autor:
Natasha van't Boveneind-Vrubleuskaya, Fajri Gafar, Onno W. Akkerman, Jan-Willem C. Alffenaar, Bob Wilffert
Publikováno v:
European Respiratory Journal, 54(4):1901402. EUROPEAN RESPIRATORY SOC JOURNALS LTD
BackgroundAs a vulnerable population, children and adolescents with tuberculosis (TB) are faced with many challenges, even those who live in low TB incidence countries. We aimed to evaluate factors associated with TB treatment outcomes allowing more
Autor:
Mathieu S. Bolhuis, Onno W. Akkerman, Tjip S. van der Werf, Wiel C M de Lange, Jan-Willem C. Alffenaar, Huib A. M. Kerstjens
Publikováno v:
European Respiratory Journal, 54(6):1900580. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Despite all our efforts, the disease burden of tuberculosis (TB) is not falling fast enough to reach the 2030 milestone of the End TB strategy [1]. Multidrug-resistant tuberculosis (MDR-TB) remains a public health crisis, with low treatment success r
Autor:
Simone H J van den Elsen, Tjip S. van der Werf, Mireille A. Wessels, Samiksha Ghimire, Daan J Touw, Mathieu S. Bolhuis, Erwin M Jongedijk, Jan-Willem C. Alffenaar, Onno W. Akkerman
Publikováno v:
European Respiratory Journal, 55(5):1901903. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Therapeutic drug monitoring using saliva as matrix is a suitable alternative for serum therapeutic drug monitoring of linezolid, but not for moxifloxacin due to a high variability in saliva-plasma ratioshttp://bit.ly/2NIYdz7