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Autor:
Ulrich Gatzemeier, Michael Boyer, Paolo Paoletti, Salih Emri, Christian Manegold, Claude Denham, Nicholas J. Vogelzang, James J. Rusthoven, James T. Symanowski, Clet Niyikiza, E. Kaukel, Pierre Ruffié
Publikováno v:
Journal of Clinical Oncology. 41:2125-2133
PURPOSE Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Autor:
Achim Lusch, Carolin Buddensieck, Yue Che, P. Albers, Andreas Hiester, C. Winter, Robert Große Siemer
Publikováno v:
Journal of Urology. 207:617-626
Purpose The oncological benefit of postchemotherapy residual tumor resection (PC-RTR) in patients with germ cell tumors and elevated serum tumor markers (STMs) remains unclear. This analysis was performed to better define patients who benefit from su
Publikováno v:
European Journal of Surgical Oncology. 48:666-671
Background Oophorectomy is a common procedure in women with peritoneal metastasis (PM) undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), which has unique consequences on hormonal balance and fertility befor
Autor:
Andrew Weaver, Steve Bandula, Ewan Brown, Alfonso Yubero Esteban, Philip Sinclair, Armeen Mahvash, Mary F. Mulcahy, Etienne Garin, Constantinos T. Sofocleous, William P. Harris, Paul Ross, Robert C.G. Martin, Amir H Montazeri, Siddharth A. Padia, Marc Pracht, Darryl Zuckerman, Ken Herrmann, Matthew S. Johnson, Gregory C. Wilson, Janet Graham, Riad Salem, Tae-You Kim, Robert J. Lewandowski, Jamie Mills
Publikováno v:
Journal of Clinical Oncology. 39:3897-3907
PURPOSE To study the impact of transarterial Yttrium-90 radioembolization (TARE) in combination with second-line systemic chemotherapy for colorectal liver metastases (CLM). METHODS In this international, multicenter, open-label phase III trial, pati
Autor:
Stéphanie Becker, Pierre Vera, Pierre Pinochet, Edgar Texte, Aspasia Stamatoullas-Bastard, Sorina-Dana Mihailescu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Our aim was to evaluate the prognostic value of initial total metabolic tumour volume (TMTV) in a population of patients with advanced-stage Hodgkin’s lymphoma (HL). We retrospectively included 179 patients with stage IIb-III-IV Hodgkin’s disease
Autor:
Horst Müller, Heinz Haverkamp, Peter Borchmann, Andreas Viardot, Jan-Michel Heger, Christine Schmitz, Bastian von Tresckow, Michael Fuchs, Dennis A. Eichenauer, Vladan Vucinic, Andreas Engert, Stephanie Sasse, Max S. Topp, Paul J Bröckelmann, Annette Plütschow, Sarah Gillessen, Boris Böll, Sven Borchmann, Carsten Kobe, Andreas Hüttmann
Publikováno v:
British Journal of Haematology. 196:606-616
Reinduction chemotherapy followed by high-dose chemotherapy and autologous stem cell transplant (HDCT + ASCT) is second-line standard of care for transplant-eligible patients with relapsed/refractory classical Hodgkin lymphoma (r/r cHL) but has a hig
Autor:
Yinhua Liu, Xuening Duan, Shuang Zhang, Yimin Cui, Zhuo Zhang, Wenjia Zhang, Hanxu Zhang, Qian Xiang, Xiaocong Pang, Qianxin Liu, Ling Xu, Hong Zhang, Chao Li
Publikováno v:
Thoracic Cancer, Vol 12, Iss 24, Pp 3396-3406 (2021)
Thoracic Cancer
Thoracic Cancer
Purpose Circulating microRNAs (miRNAs) have been indicated as predictive biomarker for the response to neoadjuvant chemotherapy (NAC) and the prognosis of breast cancer (BC); however, to date the conclusions have been controversial. The biological ch
Autor:
Qiong Lyu, Jian Zhang, Peng Luo, Ting Wei, Weimin Ding, Linlang Guo, Weiliang Zhu, Qiongyao Wang, Manming Cao
Publikováno v:
Cancer Medicine, Vol 10, Iss 21, Pp 7863-7876 (2021)
Cancer Medicine
Cancer Medicine
Background The majority of patients with small‐cell lung cancer (SCLC) show a good response in the early stages of treatment, but more than 90% of patients will develop drug resistance. Therefore, biomarkers are urgently needed to identify patients
Autor:
Seock-Ah Im, Jee Hyun Kim, Jin-Young Jang, Do-Youn Oh, Sae-Won Han, Yung-Jue Bang, Sung W. Ha, Sun Whe Kim, Jihyun Kwon, Eui Kyu Chie, Jae Sung Kim, Tae-You Kim, Kyung-Hun Lee
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Despite curative resection, the 5-year survival for patients with resectable pancreatic cancer is less than 20%. Recurrence occurs both locally and at distant sites and effective multimodality adjuvant treatment is needed.Materials and Method