Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Katia Scotlandi"'
Publikováno v:
Seminars in Cancer Biology. 60:57-71
Overexpression of ATP-binding cassette (ABC) transporters is a cause of drug resistance in a plethora of tumors. More recent evidence indicates additional contribution of these transporters to other processes, such as tumor cell dissemination and met
Autor:
Mauro Magnani, Alessandro Parra, Pier Luigi Lollini, Davide Maria Donati, Marianna L. Ianzano, Arianna Palladini, Alberto Righi, Lorena Landuzzi, Piero Picci, Katia Scotlandi, Francesca Ruzzi, Michela Pasello, Maria Cristina Manara, Patrizia Nanni, Giordano Nicoletti, Marianna Carrabotta, Manuela Ferracin, Camilla Cristalli, Veronica Giusti
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Standard therapy of osteosarcoma (OS) and Ewing sarcoma (EW) rests on cytotoxic regimes, which are largely unsuccessful in advanced patients. Preclinical models are needed to break this impasse. A panel of patient-derived xenografts (PDX) was establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddeb6f5c0f5645ab337a870087639320
http://hdl.handle.net/11585/696462
http://hdl.handle.net/11585/696462
Autor:
Maria Elena Laguardia, Mauro Magnani, Katia Scotlandi, Clara Guerzoni, Sabrina Dominici, Valentina Fiori, Michela Pasello, Maurizio Cianfriglia, Maria Cristina Manara, Damiano Cosimo Carbonella, Diego Moricoli, Maria Cristina Balducci
Publikováno v:
Applied Microbiology and Biotechnology. 100:3949-3963
Ewing's sarcoma (EWS) is the second most common primary bone tumor in pediatric patients characterized by over expression of CD99. Current management consists in extensive chemotherapy in addition to surgical resection and/or radiation. Recent improv
Autor:
José Rubio-Briones, Selena Ventura, Cecilia Garofalo, Ana Calatrava, José Antonio López-Guerrero, Irene Casanova-Salas, Katia Scotlandi, Maria Cristina Manara, Vera Magistroni, Caterina Mancarella
Publikováno v:
Europe PubMed Central
Oncotarget
Oncotarget
// Caterina Mancarella 1 , Irene Casanova-Salas 2 , Ana Calatrava 3 , Selena Ventura 1 , Cecilia Garofalo 1 , Jose Rubio-Briones 4 , Vera Magistroni 5 , Maria Cristina Manara 1 , Jose Antonio Lopez-Guerrero 2, * , Katia Scotlandi 1, * 1 CRS Developme
Autor:
Michela Pierini, Enrico Lucarelli, Barbara Dozza, Katia Scotlandi, Marina Orlandi, Alessio Papi, Giuseppina Tresca, Davide Maria Donati
Publikováno v:
Toxicology in Vitro. 26:142-149
Natural derivatives of vitamin A, including all- trans -retinoic acid (ATRA), commonly known as retinoids, currently produce favorable results in the treatment of many types of tumors. The rexinoid 6-OH-11-O-hydroxyphenantrene (IIF) is a synthetic de
Autor:
Massimo Serra, Katia Scotlandi
Publikováno v:
Cancer Letters. 284:113-121
Caveolins, essential scaffold proteins of caveolae, have emerged as versatile molecules that can influence numerous signaling pathways and disease processes. This brief review is focused on the role of caveolins in the physiology and pathology of mus
Autor:
Isabella Scionti, Francesca Michelacci, Marilù Fanelli, Massimo Serra, Katia Scotlandi, Giuseppina Stoico, Piero Picci, Michela Pasello, Daniel Remondini, Claudia Maria Hattinger, Gastone Castellani
Publikováno v:
Genes, Chromosomes and Cancer. 48:289-309
Gene amplification and copy number changes play a pivotal role in malignant transformation and progression of human tumor cells by mediating the activation of genes and oncogenes, which are involved in many different cellular processes including deve
Autor:
Piero Picci, Anna Maria Caccuri, Michela Pasello, Francesca Michelacci, Isabella Scionti, Claudia Maria Hattinger, Katia Scotlandi, Monia Zuntini, Massimo Serra
Publikováno v:
Cancer Research. 68:6661-6668
Cisplatin (cis-diamminedichloroplatinum, CDDP) is one of the most used drugs for osteosarcoma chemotherapy. By using a series of CDDP-resistant variants, which were established from the U-2OS and Saos-2 human osteosarcoma cell lines, we found that CD
Autor:
Katia Scotlandi, Piero Picci
Publikováno v:
Current Opinion in Oncology. 20:419-427
PURPOSE OF REVIEW The present review examines the rationale for targeting insulin-like growth factor-I receptor in sarcoma therapy and highlights some key issues that need to be addressed as clinical trials targeting insulin-like growth factor-I rece
Autor:
Stefania Benini, Katia Scotlandi, Maria Cristina Manara, Piero Picci, Giordano Nicoletti, Pinchas Cohen, Monia Zuntini, Youngman Oh, Patrizia Nanni
Publikováno v:
International Journal of Cancer. 119:1039-1046
The IGF/IGF-IR system plays a major role in the pathogenesis and progression of Ewing's sarcoma. In this article, the authors evaluated whether the insulin-like growth factor binding protein-3 (IGFBP-3), a molecule with growth-inhibitory and proapopt