Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Schiff, R"'
Autor:
Britta Weigelt, Resel Pereira, C. Kent Osborne, Rinath Jeselsohn, Jiangang Liu, Vidyalakshmi Sethunath, Jamunarani Veeraraghavan, Rachel Schiff, Lanfang Qin, Luca Malorni, Pier Selenica, Carmine De Angelis, Xiaoyong Fu, Ilenia Migliaccio, David N Brown, Susan G. Hilsenbeck, Sarmistha Nanda, Joshua Donaldson, Valerie M. Jansen, Sara A. Hurvitz, Agostina Nardone, Dennis J. Slamon, Ben Ho Park, Tao Wang, Jorge S. Reis-Filho, Lacey M. Litchfield, C. Guarducci, Matteo Benelli, Maria Letizia Cataldo, Mothaffar F. Rimawi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17
Purpose: Cyclin-dependent kinase 4 (CDK4) and CDK6 inhibitors (CDK4/6i) are highly effective against estrogen receptor–positive (ER+)/HER2− breast cancer; however, intrinsic and acquired resistance is common. Elucidating the molecular features of
Cancer immunology is the most rapidly expanding field in cancer research, with the importance of immunity in cancer pathogenesis now well accepted including in the endocrine-related cancers. The immune system plays an essential role in the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d0edccc5d69e4f464abc44f3066a1e
http://hdl.handle.net/11588/879945
http://hdl.handle.net/11588/879945
Autor:
Chandandeep Nagi, Hariprasad Thangavel, Mario Giuliano, Lacey E. Dobrolecki, Agostina Nardone, Carmine De Angelis, Meghana V. Trivedi, Michael T. Lewis, Rachel Schiff, Jackie L. Stilwell, C. Kent Osborne, Debashish Sahay, Sina Hedayatpour, Raksha Bhat, Eric P. Kaldjian, Mothaffar F. Rimawi, Arturo Ramirez
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Background Breast cancer patient-derived xenograft (BC-PDX) models represent a continuous and reproducible source of circulating tumor cells (CTCs) for studying their role in tumor biology and metastasis. We have previously shown the utility of BC-PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688296ce56fe9a1f54200af1da1bcffe
http://hdl.handle.net/11588/771300
http://hdl.handle.net/11588/771300
Autor:
C. Kent Osborne, Carmine De Angelis, Jorge S. Reis-Filho, Jamunarani Veeraraghavan, Aleix Prat, Mothaffar F. Rimawi, Rachel Schiff, Tomás Pascual
Overexpression and/or gene amplification of HER2, a crucial member of the HER family of four receptors, occur in about 15-20% of breast cancers and define an aggressive subtype of the disease. Activated HER homo and heterodimers govern a complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fc5b38c62a2a02712292d649c32db7
https://europepmc.org/articles/PMC6050048/
https://europepmc.org/articles/PMC6050048/
Autor:
Ilenia Migliaccio, Robin Ward, Meng-Fen Wu, Susan G. Hilsenbeck, Carolina Gutierrez, Grazia Arpino, Yen-Chao Wang, Rachel Schiff, C. Kent Osborne, Mothaffar F. Rimawi, Suleiman Massarweh, Catherine Huang, Robert D Soliz, Lisa Wiechmann
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 17(6)
Purpose: We have shown that incomplete blockade of the human epidermal growth factor (HER) pathway is a mechanism of resistance to treatment with trastuzumab (T) in HER2-overexpressing tumor xenografts. We now investigate whether the addition of lapa