Zobrazeno 1 - 10
of 268
pro vyhledávání: '"François Nosten"'
Autor:
Nicholas J. White, Mary Ellen Gilder, Kamonchanok Konghahong, Verena I. Carrara, François Nosten, Claudia Turner, Aung Myat Min, Germana Bancone, Aung Pyae Phyo, Pratap Singhasivanon, Jureeporn Duanguppama, Moo Kho Paw, Mupawjay Pimanpanarak, Makoto Saito, Cindy S. Chu, Warat Haohankhunnatham, Nay Win Tun, Sue J. Lee, Mallika Imwong, Stephane Proux, Jacher Viladpai-nguen, Rose McGready
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
BMC Medicine
BMC Medicine
Background Artemisinin and artemisinin-based combination therapy (ACT) partner drug resistance in Plasmodium falciparum have spread across the Greater Mekong Subregion compromising antimalarial treatment. The current 3-day artemether-lumefantrine reg
Autor:
Ricardo Aguas, Lisa J. White, François Nosten, Shwe Sin Kyaw, Wirichada Pan-Ngum, Olivier Celhay, Sasithon Pukrittayakamee, Yoel Lubell, Gilles Delmas, Richard J. Maude, Tom Drake
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Public Health
BMC Public Health
Background Mass drug administration (MDA) has received growing interest to accelerate the elimination of multi-drug resistant malaria in the Greater Mekong Subregion. Targeted MDA, sometimes referred to as focal MDA, is the practice of delivering MDA
Autor:
Raahil S. Patel, Brice Campo, Jetsumon Sattabongkot, Steven P. Maher, Chris Palmiotti, Chiara Andolina, Rays H. Y. Jiang, Alison Roth, Phillip Cualing, Dennis E. Kyle, Jessica Turgeon, Robert Carter, John H. Adams, Swamy R. Adapa, Wajeeh M. Saadi, Virginia Van Grod, François Nosten, Amy J. Conway, Myles E. Johnson, Samantha J. Barnes, Naresh Singh, H-C Steve Sun, Victor Chaumeau, James C. Hsiao
Publikováno v:
Lab on a Chip. 20:1124-1139
Advanced cell culture methods for modeling organ-level structure have been demonstrated to replicate in vivo conditions more accurately than traditional in vitro cell culture. Given that the liver is particularly important to human health, several ad
Autor:
Jureeporn Duanguppama, James A Watson, Nicholas J. White, Caroline O. Buckee, Nicholas P. J. Day, François Nosten, Daniel E. Neafsey, Cindy S. Chu, Mallika Imwong, Aimee R. Taylor, Kanokpich Puaprasert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection following treatment can be hypnozoite-derived (relapse), a blood-stage
Autor:
Kanokpich Puaprasert, Htun Htun Win, François Nosten, Suradet Thinraow, Widi Yotyingaphiram, Pornpimon Wilaisrisak, Joel Tarning, Aye Aye Aung, Mallika Imwong, James A Watson, Cindy S. Chu, Daniel Blessborn, Stephane Proux, Nicholas J. White, Aung Pyae Phyo, Nay Lin Soe, Clare L. Ling, Warunee Hanpithakpong
Publikováno v:
Antimicrobial agents and chemotherapy
BackgroundPrimaquine is the only widely available drug for radical cure of Plasmodium vivax malaria. There is uncertainty whether the pharmacokinetic properties of primaquine are altered significantly in childhood or not.MethodsGlucose-6-phosphate de
Autor:
Adeline C. Y. Chua, Saorin Kim, Bruce Russell, Eakpor Piv, Sivkeng Ouk, Rays H. Y. Jiang, Zaira Rizopoulos, Dennis E. Kyle, Sivchheng Phal, Pablo Bifani, Bros Doeurk, Amélie Vantaux, Julie Péneau, Nana Akua Awuku, Sangrawee Suriyakan, Brice Campo, Benoit Witkowski, Chansophea Chhin, Mélanie Rouillier, Sreyvouch Phen, Chantrea Vong, Praphan Kittiphanakun, Steven P. Maher, François Nosten, Chiara Andolina, Amy J. Conway, Caitlin A. Cooper, Baura Tat, Victor Chaumeau
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.19905. ⟨10.1038/s41598-021-99152-9⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several compound lib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d351b9c26631b1545f18c69ca7cb66
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03491954/document
Autor:
Jordi Landier, Thomas J. Peto, Frank Smithuis, Mavuto Mukaka, Mark Debackere, Walter R. J. Taylor, Lorenz von Seidlein, Arnaud Tarantola, Tran Tinh Hien, Arjen M. Dondorp, Rupam Tripura, Arantxa Roca-Feltrer, Koukeo Phommasone, Pimnara Peerawaranun, Sim Kheng, François Nosten, Nicholas J. White, Philippe Buchy, Joel Tarning, Sinoun Muth, Lek Dysoley, Soy Ty Kheang, Thuy Nguyen, Didier Menard, Ngak Song, Chy Say, Leang Rithea, Mayfong Mayxay, Kak Neeraj, Rick M. Fairhurst, Richard M. Hoglund
Publikováno v:
Malaria journal, 20(1):366. BioMed Central
Malaria Journal
Malaria Journal, 2021, 20 (1), pp.366. ⟨10.1186/s12936-021-03886-w⟩
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Malaria Journal, BioMed Central, 2021, 20 (1), pp.366. ⟨10.1186/s12936-021-03886-w⟩
Malaria Journal
Malaria Journal, 2021, 20 (1), pp.366. ⟨10.1186/s12936-021-03886-w⟩
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Malaria Journal, BioMed Central, 2021, 20 (1), pp.366. ⟨10.1186/s12936-021-03886-w⟩
Background In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed target doses of 0.25 or 0.5 mg/kg/day of primaquine for 14 days in gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e290e5a1b236134f2743a06296dc950
https://doi.org/10.1186/s12936-021-03886-w
https://doi.org/10.1186/s12936-021-03886-w
Autor:
François Nosten, Bernett Lee, Wenn-Chyau Lee, Aung Pyae Phyo, Bruce Russell, Laurent Rénia, Cindy S. Chu, Kanlaya Sriprawat, Yee Ling Lau
Publikováno v:
EBioMedicine
Background: Artemisinin (ART) resistance in Plasmodium falciparum is thought to occur during the early stage of the parasite's erythrocytic cycle. Here, we identify a novel factor associated with the late stage parasite development that contributes t
Autor:
Jordi Landier, Abdullah Abu Sayeed, Seila Suon, Kim-Tuyen Nguyen, Kate Rowlands, Frank Smithuis, Chanon Kunasol, Chanaki Amaratunga, Sasithon Pukrittayakamee, Keobouphaphone Chindavongsa, Jacob Almagro Garcia, Richard D. Pearson, Mozam Ali, Xin Hui S Chan, Katie Love, Naomi Park, Pascal Ringwald, Richard J. Maude, Cristina V. Ariani, Mehul Dhorda, Marie A. Onyamboko, Daniel M. Parker, Tin Maung Hlaing, Scott Goodwin, Namfon Kotanan, Thang Ngo Duc, Gilles Delmas, Huy Rekol, Rick M. Fairhurst, Victoria Simpson, Arjen M. Dondorp, Le Thanh Dong, Bouasy Hongvanthong, Tran Tinh Hien, Rapeephan R. Maude, Thomas J. Peto, Shavanthi Rajatileka, Roberto Amato, Thanat Chookajorn, Ben Jeffery, Anna E. Jeffreys, Nicole Zdrojewski, Caterina I. Fanello, Eleanor Drury, Mihir Kekre, Myo Thant, John Sillitoe, Olivo Miotto, Aung Myint Thu, James J Callery, Subrata Baidya, Paul N. Newton, Ranitha Vongpromek, Prativa K Behera, Borimas Hanboonkunupakarn, Rob W. van der Pluijm, Jim Stalker, Anupkumar R. Anvikar, Sonexay Phalivong, Dawn Muddyman, Nguyen Thuy-Nhien, Christina Hubbart, Rithea Leang, Lorenz von Seidlein, Nicholas P. J. Day, Phrutsamon Wongnak, Jonathan Keatley, Hoa Nguyen, Cinzia Malangone, Parthasarathi Satpathi, Abul Faiz, Dysoley Lek, François Nosten, Christopher G Jacob, Rupam Tripura, Sara E. Canavati, Huynh Hong Quang, Kirk A. Rockett, Neena Valecha, Thuy Nguyen, Kimberly J. Johnson, Tran Minh Nhat, Didar Uddin, Caroline O. Buckee, Akhter ul Islam, Podjanee Jittamala, Mayfong Mayxay, Amir Hossain, Viengxay Vanisaveth, Elizabeth A. Ashley, Dominic P. Kwiatkowski, Sanghamitra Satpathi, Aung Pyae Phyo, Amar Tripura, Nguyen Hoang Chau, Sónia Gonçalves, Khin Lin, Cheah Huch
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2021, 10, pp.e62997. ⟨10.7554/elife.62997⟩
eLife, 2021, 10, pp.e62997. ⟨10.7554/elife.62997⟩
eLife, Vol 10 (2021)
eLife, eLife Sciences Publication, 2021, 10, pp.e62997. ⟨10.7554/elife.62997⟩
eLife, 2021, 10, pp.e62997. ⟨10.7554/elife.62997⟩
eLife, Vol 10 (2021)
Author(s): Jacob, Christopher G; Thuy-Nhien, Nguyen; Mayxay, Mayfong; Maude, Richard J; Quang, Huynh Hong; Hongvanthong, Bouasy; Vanisaveth, Viengxay; Ngo Duc, Thang; Rekol, Huy; van der Pluijm, Rob; von Seidlein, Lorenz; Fairhurst, Rick; Nosten, Fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5316f82b160e00468fb81cc7d9f11976
https://www.hal.inserm.fr/inserm-03451958
https://www.hal.inserm.fr/inserm-03451958
Autor:
Nicholas J. White, François Nosten
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-4 (2021)
Malaria Journal
Malaria Journal
Single Encounter Radical Cure and Prophylaxis (SERCAP) describes an ideal anti-malarial drug that cures all malaria in a single dose. This target product profile has dominated anti-malarial drug discovery and development over the past decade. The ope