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Autor:
Jack F. Shern, Meera Murgai, Terry J. Fry, Alec J. Walker, M. Eric Kohler, Rimas J. Orentas, Crystal L. Mackall, Maria Ingaramo, Rosandra N. Kaplan, Kelsey Wanhainen, Adrienne H. Long, Waleed Haso, Jillian P. Smith, George H. Patterson, Vikas R Venkateshwara
Publikováno v:
Nature medicine
Chimeric antigen receptors (CARs) targeting CD19 have mediated dramatic antitumor responses in hematologic malignancies, but tumor regression has rarely occurred using CARs targeting other antigens. It remains unknown whether the impressive effects o