Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julia Jellusova"'
Autor:
Amélie Bonaud, Laetitia Gargowitsch, Simon M. Gilbert, Elanchezhian Rajan, Pablo Canales-Herrerias, Daniel Stockholm, Nabila F. Rahman, Mark O. Collins, Hakan Taskiran, Danika L. Hill, Andres Alloatti, Nagham Alouche, Stéphanie Balor, Vanessa Soldan, Daniel Gillet, Julien Barbier, Françoise Bachelerie, Kenneth G. C. Smith, Julia Jellusova, Pierre Bruhns, Sebastian Amigorena, Karl Balabanian, Michelle A. Linterman, Andrew A. Peden, Marion Espéli
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (2), pp.e2213056120. ⟨10.1073/pnas.2213056120⟩
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (2), pp.e2213056120. ⟨10.1073/pnas.2213056120⟩
Despite the essential role of plasma cells in health and disease, the cellular mechanisms controlling their survival and secretory capacity are still poorly understood. Here, we identified the soluble N-ethylmaleimide-sensitive factor attachment prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f62eb6890c17956c3a9822f5a059b5a
https://hal.science/hal-04064289v1/document
https://hal.science/hal-04064289v1/document
Autor:
Ju Liu, Yukai Jing, Lu Yang, Jiang Chang, Julia Jellusova, Na Li, Panpan Jiang, Lisa S. Westerberg, Anwei Chen, Cong-Yi Wang, Qiuyue Chen, Danqing Kang, Xi Luo, Chaohong Liu, Heather Miller, Quan Gong
Publikováno v:
Cellular and Molecular Life Sciences. 77:4379-4395
As an important chemokine receptor, the role of CX3CR1 has been studied extensively on the migration of lymphocytes including T and B cells. Although CX3CR1+ B cells have immune suppressor properties, little is known about its role on the regulation
Autor:
Melanie Boerries, Sebastian N. Steiner, Michael Reth, Bernd Wollscheid, Jonas B. Albinus, Reinhard E. Voll, Kathrin Kläsener, Marco Cavallari, Julia Jellusova, Geoffroy Andrieux, Ulrich Salzer, Beatrix Süß, Chiara Böhler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118 (7)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies for B cell depletion therapies, the biological function of their target remains unclear. Here,
Autor:
Kathrin Kläsener, Geoffroy Andrieux, Julia Jellusova, Michael Reth, Bernd Wollscheid, Chiara Boehler, Reinhard E. Voll, Beatrix Suess, Ulrich Salzer, Jonas B Albinus, Sebastian N Steiner, Marco Cavallari, Melanie Boerries
CD20 is a B cell specific membrane protein and a target of therapeutic antibodies such as rituximab (RTX). In spite of the prominent usage of anti-CD20 antibodies in the clinic little is known about the biological function of CD202. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2182b8137422d9d1685dd21328c54193
https://doi.org/10.1101/2020.07.31.230110
https://doi.org/10.1101/2020.07.31.230110
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes
Autor:
Markus Köhler, Laura Hoenig, Anja E. Hauser, Kathrin Brenker, Ellen McAllister, Deniz Saltukoglu, Marieta Caganova, Huda Jumaa, Xiaocui He, Michael Reth, Ruth Leben, Klaus Rajewsky, Raluca A. Niesner, Julia Jellusova
Publikováno v:
Life Science Alliance
Immunoglobulins shape mitochondrial function by driving ER expansion, this form of metabolic control is independent of the role the immunoglobulins play as part of the antigen receptor on the cell surface.
The major function of B lymphocytes is
The major function of B lymphocytes is
Publikováno v:
The Journal of Immunology. 199:2998-3003
B cells contribute critically to an effective immune response by producing antigen-specific antibodies. During the immune response to so-called thymus dependent antigens, activated B cells seek T cell help and form germinal centers. In contrast, thym
Autor:
Numana Bhat, Ashima Shukla, Wai W Lin, Cindi Chen, Robert C. Rickert, Elaine Kao, Charlotte R Leung, John R Apgar, Julia Jellusova
Publikováno v:
JCI Insight. 4
Immune homeostasis in the gut-associated lymphoid tissues (GALT) is critical to prevent the development of inadvertent pathologies. B cells, as the producers of antibodies and cytokines, play an important role in maintaining the GALT homeostasis. How
Autor:
Erika Lattová, Vic Spicer, Julia Jellusova, Dorota Bartusik, Hélène Perreault, Boguslaw Tomanek
Publikováno v:
Molecularcellular proteomics : MCP. 10(9)
The therapeutic humanized monoclonal antibody IgG1 known as Herceptin® has shown remarkable antitumor effects. Although this type of therapy has increased the cancer-free survival of patients, not all tumors respond to this treatment and cancers oft
Autor:
Sheena C. Kerr, Jiquan Zhang, Anja Hoffmann, Florian Weisel, Paul R. Crocker, Lars Nitschke, Thomas Winkler, Julia Jellusova, Burkhard Kneitz, Ute Wellmann
Publikováno v:
Nature immunology. 8(7)
B1 cells are an important cell population for the production of natural antibodies and for antibacterial immunoglobulin responses. Here we identified the mouse protein Siglec-G as a B1 cell inhibitory receptor. Siglec-G was expressed in a B cell–re