Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victoria Majam"'
Autor:
Gabrielle Walsh, Wenshuo Zhou, Alexei Medvedev, Barbara K. Felber, Sanjai Kumar, Jasper Perry-Anderson, Victoria Majam, Konstantin Virnik, Ira Berkower
Publikováno v:
Biochem Biophys Res Commun
There is an urgent need for a malaria vaccine that can prevent severe disease in young children and adults. Despite earlier work showing an immunological mechanism for preventing infection and reducing disease severity, there is currently no reliable
Autor:
Martha Sedegah, Richard L. Shimp, Miranda S. Oakley, Victoria Majam, Arnel Belmonte, Bhavna Chawla, David C. Kaslow, Babita Mahajan, Sanjai Kumar
The development of effective malaria vaccines is hampered by incomplete understanding of the immunological correlates of protective immunity. Recently, the moderate clinical efficacy of the Plasmodium falciparum circumsporozoite protein (CSP)-based R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed838bd34e158368b145ec58064403bc
https://europepmc.org/articles/PMC6759290/
https://europepmc.org/articles/PMC6759290/
Autor:
Sanjai Kumar, Tanjir Islam, Sharareh Eskandari, Michael R. Batzloff, Istvan Toth, Mei Fong Ho, Victoria Majam, Danielle I. Stanisic, Ali Zaid, Hanan A Al-Nazal, Waleed M. Hussein, Mariusz Skwarczynski, Michael F. Good, Emily Cooper, Ashwini Kumar Giddam
Publikováno v:
Cell Host & Microbe. 29:894-903.e5
Babesia spp. are tick-transmitted intra-erythrocytic protozoan parasites that infect humans and animals, causing a flu-like illness and hemolytic anemia. There is currently no human vaccine available. People most at risk of severe disease are the eld
Autor:
Victoria Majam, Christian F. Ockenhouse, Anjali Yadava, Sanjai Kumar, Michael A Washington, Hong Zheng, Lisa A. Ware, Jetsumon Sattabongkot
Publikováno v:
Infection and Immunity. 75:1177-1185
A successful vaccine againstPlasmodium vivaxmalaria would significantly improve the health and quality of the lives of more than 1 billion people around the world. A subunit vaccine is the only option in the absence of long-term culture ofP. vivaxpar
Autor:
Victoria Majam, Chris F. Ockenhouse, Thomas L. Richie, Daniel J. Carucci, Mara P. Berzins, Judith E. Epstein, Kent E. Kester, Stephen L. Hoffman, Joe Cohen, Harini Ganeshan, Jennifer Ng, Trevor R. Jones, Ruobing Wang, Rhonda Newcomer, D. Gray Heppner, Yupin Charoenvit, Nadia Tornieporth, Esteban Abot, Steve Fitzpatrick, Carolyn A. Holland, Jon Norman, C.Nicole Freydberg
Publikováno v:
Vaccine. 22:1592-1603
Optimal protection against malaria may require induction of high levels of protective antibody and CD8(+) and CD4(+) T cell responses. In humans, malaria DNA vaccines elicit CD8(+) cytotoxic T cells (CTL) and IFNgamma responses as measured by short-t
Autor:
Martha Sedegah, John B. Sacci, Kalpana Gowda, Sanjai Kumar, Victoria Majam, John A. Tine, Peter Hobart, Richard C. Hedstrom, Yupin Charoenvit, Stephen L. Hoffman, Walter R. Weiss
Publikováno v:
The Journal of Immunology. 164:5905-5912
Intramuscular immunization with a naked DNA plasmid expressing the Plasmodium yoelii circumsporozoite protein (pPyCSP) protects mice against challenge with P. yoelii sporozoites. This protection can be improved either by coadministration of a plasmid
Autor:
Fanny Guzman, Esteban Abot, Giampietro Corradin, John B. Sacci, Denise L. Doolan, Stephen L. Hoffman, Victoria Majam, Trevor R. Jones, Manuel E. Patarroyo, Ruobing Wang, Yupin Charoenvit
Publikováno v:
Infection and Immunity. 67:5604-5614
Most work on protective immunity against the pre-erythrocytic stages of malaria has focused on induction of antibodies that prevent sporozoite invasion of hepatocytes, and CD8 + T-cell responses that eliminate infected hepatocytes. We recently report
Autor:
Jay A. Berzofsky, Babita Mahajan, Robert A. Boykins, J. David Haynes, Hong Zheng, Patricia De La Vega, J. Kathleen Moch, Rana Chattopadhyay, Victoria Majam, Sanjai Kumar, Igor M. Belyakov, Hira L. Nakhasi
The multiple antigen peptide (MAP) approach is an effective method to chemically synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunogen. Here we report on the design, chemical synthesis, and immunogenicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eb5d9507a7be031efd389319e2ab6d
https://europepmc.org/articles/PMC2976343/
https://europepmc.org/articles/PMC2976343/
Autor:
Stephen L. Hoffman, Joao C. Aguiar, William O. Rogers, Victoria Majam, Richard C. Hedstrom, Yupin Charoenvit, David E. Lanar, John B. Sacci, Richard Stout
Publikováno v:
Vaccine. 20(1-2)
We compared the needle free jet device device Biojector with syringe/needle as a method to administer a DNA vaccine encoding the Plasmodium falciparum circumsporozoite protein (PfCSP) in albino rabbits. A group of three rabbits was injected by the in