Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Angela R. Corrigan"'
Autor:
Nicole A. Doria-Rose, Cheng Cheng, Tyler Stephens, Shuishu Wang, Steven J. Chen, Peter D. Kwong, John Paul Todd, Christopher A. Gonelli, Amarendra Pegu, Sijy O'Dell, Richard A. Koup, Vrc Production Program, Kai Xu, Baoshan Zhang, John R. Mascola, Adrian B. McDermott, Hongying Duan, Jelle van Schooten, Li Ou, Jeffrey C. Boyington, Manjula Basappa, Angela R. Corrigan, Sarah O’Connell, Sandeep Narpala, Kathryn E. Foulds, Megan E. DeMouth, Marit J. van Gils, Yaroslav Tsybovsky, Tongqing Zhou, Hui Geng
Publikováno v:
Cell reports, 35(1):108937. Cell Press
Cell Reports, Vol 35, Iss 1, Pp 108937-(2021)
Cell reports
Cell Reports, Vol 35, Iss 1, Pp 108937-(2021)
Cell reports
SUMMARY Soluble “SOSIP”-stabilized envelope (Env) trimers are promising HIV-vaccine immunogens. However, they induce high-titer responses against the glycan-free trimer base, which is occluded on native virions. To delineate the effect on base re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25456efa28d5031ea6efc66dceedf09
https://pure.amc.nl/en/publications/fusion-peptide-priming-reduces-immune-responses-to-hiv1-envelope-trimer-base(8874d9ca-be54-4482-9c96-b1171a7bdf93).html
https://pure.amc.nl/en/publications/fusion-peptide-priming-reduces-immune-responses-to-hiv1-envelope-trimer-base(8874d9ca-be54-4482-9c96-b1171a7bdf93).html
Autor:
Li Ou, Jeffrey C. Boyington, Michael Chambers, Yongping Yang, John R. Mascola, Adam S. Olia, Stephen D. Schmidt, Peter D. Kwong, Shuishu Wang, Anita Changela, Rui Kong, Cheng Cheng, Angela R. Corrigan, Edward K Sarfo, Gwo-Yu Chuang, Nicole A. Doria-Rose, Yaroslav Tsybovsky, Raffaello Verardi, Winston Wu, Reda Rawi, Hui Geng, Adrian B. McDermott, Sandeep Narpala, Baoshan Zhang, Yen-Ting Lai, Kai Xu
Publikováno v:
J Virol
HIV-1 envelope (Env) trimers, stabilized in a prefusion-closed conformation, can elicit humoral responses capable of neutralizing HIV-1 strains closely matched in sequence to the immunizing strain. One strategy to increase elicited neutralization bre
Autor:
Edward K Sarfo, Nicole A. Doria-Rose, Diana G. Scorpio, Raffaello Verardi, Sijy O'Dell, Michael Worobey, Yaroslav Tsybovsky, Kathryn E. Foulds, Gwo-Yu Chuang, Frank J. Arnold, Cheng Cheng, Tongqing Zhou, Li Ou, Hui Geng, Winston Wu, Kevin Liu, John Paul Todd, Alexander J. Jafari, Michael Chambers, Richard A. Koup, Adrian B. McDermott, Peter D. Kwong, Xuejun Chen, Kurt R. Hill, Hongying Duan, Rui Kong, Shuishu Wang, Vrc Production Program, Yiran Wang, Anita Changela, Lawrence Shapiro, Angela R. Corrigan, Kai Xu, John R. Mascola
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107981-(2020)
Summary: The HIV fusion peptide (FP) is a promising vaccine target. FP-directed monoclonal antibodies from vaccinated macaques have been identified that neutralize up to ∼60% of HIV strains; these vaccinations, however, have involved ∼1 year with
Autor:
Rui Kong, Hongying Duan, Zizhang Sheng, Kai Xu, Priyamvada Acharya, Xuejun Chen, Cheng Cheng, Adam S. Dingens, Jason Gorman, Mallika Sastry, Chen-Hsiang Shen, Baoshan Zhang, Tongqing Zhou, Gwo-Yu Chuang, Cara W. Chao, Ying Gu, Alexander J. Jafari, Mark K. Louder, Sijy O’Dell, Ariana P. Rowshan, Elise G. Viox, Yiran Wang, Chang W. Choi, Martin M. Corcoran, Angela R. Corrigan, Venkata P. Dandey, Edward T. Eng, Hui Geng, Kathryn E. Foulds, Yicheng Guo, Young D. Kwon, Bob Lin, Kevin Liu, Rosemarie D. Mason, Martha C. Nason, Tiffany Y. Ohr, Li Ou, Reda Rawi, Edward K. Sarfo, Arne Schön, John P. Todd, Shuishu Wang, Hui Wei, Winston Wu, James C. Mullikin, Robert T. Bailer, Nicole A. Doria-Rose, Gunilla B. Karlsson Hedestam, Diana G. Scorpio, Julie Overbaugh, Jesse D. Bloom, Bridget Carragher, Clinton S. Potter, Lawrence Shapiro, Peter D. Kwong, John R. Mascola
Publikováno v:
Cell. 178:567-584.e19
The vaccine-mediated elicitation of antibodies (Abs) capable of neutralizing diverse HIV-1 strains has been a long-standing goal. To understand how broadly neutralizing antibodies (bNAbs) can be elicited, we identified, characterized, and tracked fiv
Autor:
Barton F. Haynes, Cheng Cheng, Gwo-Yu Chuang, Edward K Sarfo, Nicole A. Doria-Rose, Stephen D. Schmidt, Kevin O. Saunders, Lawrence Shapiro, Sijy O'Dell, Angela R. Corrigan, Kai Xu, Peter D. Kwong, John R. Mascola, Ariana P. Rowshan, Shuishu Wang, Li Ou, Baoshan Zhang, Reda Rawi, Rui Kong, Alexander J. Jafari, Winston Wu, Kurt R. Hill, Hui Geng, Mallika Sastry, Diana G. Scorpio
Publikováno v:
PLOS ONE. 14:e0215163
The vaccine elicitation of broadly neutralizing responses is a central goal of HIV research. Recently, we elicited cross-clade neutralizing responses against the N terminus of the fusion peptide (FP), a critical component of the HIV-entry machinery.