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pro vyhledávání: '"Kana Yasufuku"'
Autor:
Tsutomu Suzuki, Hirokazu Mishima, Mika Kobayashi, Masahide Fujita, Yasuhide Morioka, Motoji Kitaura, Katsumi Koike, Kana Yasufuku, Shino Takenouchi, Hiroki Chiba, Minoru Hasegawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1746-1751
Tramadol is a weak opioid that produces analgesic effect via both the μ-opioid receptor (MOR) and non-opioid targets. Constipation is the most common opioid-related side effect in patients with cancer and non-cancer pain. However, the contribution o