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Autor:
Stefan Klein, Isabella Gashaw, Paul Marsden, Christian Friedrich, Lorcan McGarvey, Alyn H. Morice, Klaus Francke, J W K Van Den Berg, Surinder S. Birring, Alice M Turner, Pascal Wielders
Publikováno v:
Airway pharmacology and treatment.
Background: ATP activates purinergic P2X receptors and is considered an important mediator in refractory chronic cough (RCC). We report a Phase 2a trial of BAY 1902607, a P2X3 receptor antagonist with high selectivity, in RCC. Methods: This double-bl