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Publikováno v:
Behavioral Neuroscience. 135:359-368
We previously reported that the dorsal raphe nucleus (DRN) was involved in the regulation of maternal care in lactating female mice. The DRN receives multiple innervations from a variety of the brain regions. Corticotropin-releasing factor (CRF) Type
Publikováno v:
Physiol Res
The pathogenesis of hepatic encephalopathy (HE) has been generally linked to blood ammonia, gamma-aminobutyric acid and serotonin. However, the exact mechanism remains unclear. In the present study, we aimed to explore the role of hippocampal dopamin
Autor:
Maurizio Casarrubea, Giuseppe Di Giovanni, Gabriele Deidda, Massimo Pierucci, Roberto Colangeli, Roberto Di Maio
Publikováno v:
Neurobiology of Disease, Vol 125, Iss, Pp 135-145 (2019)
Endocannabinoids (eCBs) and serotonin (5-HT) play a neuromodulatory role in the central nervous system. Both eCBs and 5-HT regulate neuronal excitability and their pharmacological potentiation has been shown to control seizures in pre-clinical and hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4b456ca16581e0886cf83806502b4e
http://hdl.handle.net/10447/339133
http://hdl.handle.net/10447/339133
Publikováno v:
Pharmacology, biochemistry, and behavior. 175
Maternal behavior is a highly motivated and well-organized social behavior. Although previous studies have shown that 5‑hydroxytryptamine 2A/2C (5-HT2A/2C) receptors play an important role in mediating the expression of normal maternal behavior, th
Autor:
Ana Paula Dambros Taschetto, Rafael Appel Flores, Brunno Rocha Levone, Larissa Kochenborger, Eduardo Simão da Silva, Moacir Serralvo Faria, Marta Aparecida Paschoalini
Publikováno v:
Behavioural pharmacology. 29(5)
The present study investigated the effects of estradiol (E2) on ingestive behavior after activation of 5-HT1A receptors in the lateral hypothalamus (LH) of female rats habituated to eat a wet mash diet. Ovariectomized rats treated with corn oil (OVX)
Autor:
Samira Schultz Mansur, Eduardo Simão da Silva, Moacir Serralvo Faria, Mariana Graciela Terenzi, Brunno Rocha Levone, Elisa Caroline Cella, Marta Aparecida Paschoalini, Ana Paula Dambros Taschetto, Larissa Kochenborger
Publikováno v:
Neuropharmacology. 89:136-145
The present study evaluated the involvement of α-adrenoceptors of the median raphe nucleus (MRN) in satiated rats, in food and water intake and motor behaviour. Control groups were treated with saline (SAL) or adrenaline (ADR), injected into the MRN
Publikováno v:
Neurogastroenterology & Motility. 27:30-39
Background Corticotropin-releasing hormone (CRH) and its receptor 1 (CRH-R1) play an important role in the colonic response to stress. The central nucleus of the amygdala (CeA) is a major extrahypothalamic site that contains a large number of neurons
Publikováno v:
Neuroscience Bulletin. 30:401-408
Status epilepticus (SE) is a life-threatening neurological emergency associated with a high mortality rate. The serotonin 1A (5-HT1A) receptor is a possible target for the treatment of SE, but its role in animal models and the precise area of brain i
Autor:
Agnieszka Zelek-Molik, Grzegorz Hess, Bartosz Bobula, Krzysztof Tokarski, Irena Nalepa, Grzegorz Satała, Magdalena Kusek, Piotr Chmielarz, Beata Duszyńska
Publikováno v:
Pharmacological Reports. 64:256-265
Background SB 269970, a 5-HT 7 receptor antagonist may produce a faster antidepressant-like effect in animal models, than do antidepressant drugs, e.g., imipramine. The present work was aimed at examining the effect of single and repeated (14 days) a
Autor:
Tomiki Sumiyoshi, Takashi Uehara, Dan Rujescu, Tomonori Seo, Tadasu Matsuoka, Just Genius, Hiroko Itoh
Publikováno v:
Synapse. 66:408-417
Decreased activity of the medial prefrontal cortex (mPFC) has been considered a basis for core symptoms of schizophrenia, an illness associated with a neurodevelopmental origin. Evidence from preclinical and clinical studies indicates that serotonin