Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Yuji Suzuki"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2544
The liver has a remarkable regenerative capacity with different modes of regeneration according to the type and extent of an injury. It has been reported that mature hepatocytes could transdifferentiate into a cholangiocyte phenotype. Sry HMG box pro
Publikováno v:
FEBS Letters. 595:1313-1321
The molecular mechanisms generating the mania-like abnormal behaviors caused by diacylglycerol (DG) kinase (DGK) η deficiency remain unclear. Here, we found that DGKη knockout markedly increased dopamine (DA) levels in the midbrain (DA-producing re
Autor:
Naoki Segi, Tomoya Ozaki, Yuji Suzuki, Jun Ouchida, Shiro Imagama, Kenji Kadomatsu, Kazuma Sakamoto
Publikováno v:
Experimental neurology. 354
The autophagy-lysosome pathway is a cellular clearance system for intracellular organelles, macromolecules and microorganisms. It is indispensable for cells not only to maintain their homeostasis but also to achieve more active cellular processes suc
Autor:
Jo Kanazawa, Keisuke Kakisaka, Yuji Suzuki, Takehiro Yonezawa, Hiroaki Abe, Ting Wang, Yasuhiro Takikawa
Publikováno v:
The Journal of Nutritional Biochemistry. 107:109052
Non-alcoholic fatty liver disease (NAFLD), the hepatic phenotype of metabolic syndrome, has been identified as a major health concern as the number of cirrhosis and deaths associated with NAFLD is expected to increase. Although fructose intake has be
Autor:
Kazuhiro Horii, Takahiko Shiina, Shouichiro Saito, Yuuki Horii, Yuji Suzuki, Hiroki Shimaoka, Yasutake Shimizu, Sawa Onouchi
Publikováno v:
The Journal of Veterinary Medical Science
The aim of the present study was to clarify roles of ATP-dependent potassium channels (KATP channels) in motility of the striated muscle portion in the esophagus. An isolated segment of the rat esophagus was placed in an organ bath and mechanical res
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Details of the posterior eye water dynamics are unclear. Aquaporin-4 (AQP4), a water channel, plays an important role in water dynamics in the central nervous system and is also present in the ocular tissue. The purpose of this study was to r
Autor:
Kyohei Higashi, Toshihiko Toida, Risa Nonaka, Taihei Yamada, Aurelien Kerever, Frederic Mercier, Yusuke Yoshimura, Eri Arikawa-Hirasawa, Yuji Suzuki
Publikováno v:
Journal of Neurochemistry. 142:534-544
Adult neurogenesis in the subventricular zone of the lateral ventricle decreases with age. In the subventricular zone, the specialized extracellular matrix structures, known as fractones, contact neural stem cells and regulate neurogenesis. Fractones
Autor:
Kohei Kume, Yasuhiro Takikawa, Hirokatsu Katagiri, Satoshi Nishizuka, Yuji Suzuki, Ting Wang, Keisuke Kakisaka
Publikováno v:
Laboratory Investigation. 96:1211-1222
Partial hepatectomy models in mice have been widely used for liver regeneration studies. A typical procedure removes ~2/3 of the liver by lobular ligation without tissue dissection. However, hepatectomy in humans involves physical damage (ie, physica
Publikováno v:
Advances in experimental medicine and biology. 1103
Cellular compensation from extrahepatic resources is expected to improve the prognosis of liver diseases. Currently, liver dysfunction is treated by a variety of modalities including drugs, cytokines, vascular interventions, energy devices, surgery,
Autor:
Hiroki Shimaoka, Yasutake Shimizu, Hiroyuki Nakamori, Takahiko Shiina, Kazuhiro Horii, Yuuki Sano, Yuji Suzuki, Kiyotada Naitou
Publikováno v:
Neurogastroenterology & Motility. 28:1641-1648
Background Serotonin (5-hydroxytryptamine, 5-HT) is a regulatory factor in motility of the gastrointestinal tract including the esophagus. Although we proposed that vagal cholinergic and mast cell-derived non-cholinergic components including serotoni