Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xinghai Yang"'
Autor:
Xinghai Yang, Pingting Zhou, Haifeng Wei, Tianrui Chen, Jianru Xiao, Bo Li, Jian Jiao, Xu Kehan, Wei Xu, Wei Wan
Publikováno v:
International Journal of Biological Sciences
Metformin, an ancient drug commonly used for treating type II diabetes, has been associated to anti-cancer capacity in a variety of developing cancers, though the mechanism remains elusive. Here, we aimed to examine the inhibitory effect of metformin
Autor:
Xiaopan Cai, Wei Xu, Jianru Xiao, Xinghai Yang, Cong Jiang, Lei Li, Tianhui Hou, Haifeng Wei, Jialin Li, Tielong Liu
Publikováno v:
Stem Cells. 37:582-592
The tumor-initiating cells (TICs) are a cell population that can initiate tumor occurrence, mediate drug resistance, and give rise to metastasis. FOXD3 is a forkhead box (Fox) transcription factor family that regulates the pluripotency of embryonic s
Autor:
Ming Qian, Chenglong Zhao, Zhixiang Wu, Jianru Xiao, Haifeng Wei, Zhenxi Li, Jian Zhao, Xinghai Yang, Mingyao Liu, Dongsheng Wang
Publikováno v:
Pharmacological research. 171
Rheumatoid arthritis (RA) is an autoimmune disease mainly characterized as chronic inflammation of joint. Both genetic and environmental factors play important roles in RA progression. G protein-coupled receptor 54 (GPR54) and Kisspeptins (KPs), the
Autor:
Xinghai Yang, Yan Li, Zhou Zhenhua, Jianru Xiao, Xu Yan, Haifeng Wei, Xudong Wang, Cheng Yang
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 143:1959-1969
Osteosarcoma is one of the most common malignancies in bones and is often found in limbs. Until now, it is not clear why osteosarcoma is rare in the spine. On the other hand, previous biological characteristics study about osteosarcoma of spine was a
Autor:
Chen Huaizhu, Yang Shouzhen, Zudong Sun, Xinghai Yang, Tang Xiangmin, Zeng Weiying, Jiangrong Tao, Lai Zhenguang
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2966 (2019)
Volume 20
Issue 12
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2966 (2019)
Soybean is one of the most important oil crops in the world. Bean pyralid is a major leaf-feeding insect of soybean. In order to screen out the functional genes and regulatory pathways related to the resistance for bean pyralid larvae, the small RNA
Autor:
Xinghai Yang, Jian Wang, Zhitao Han, Ting Wang, Haiyi Gong, Bai Guangjian, Guanghui Chen, Tielong Liu, Wang Zhou, Jianru Xiao, Shuai Han
Publikováno v:
International Journal of Molecular Medicine
Bone metastasis occurs in ~40% patients with non-small cell lung cancer (NSCLC), resulting in serious morbidity and mortality. Sclerostin domain-containing protein 1 (SOSTDC1) has been demonstrated to be associated with the development and progressio
Autor:
Xin Gao, Shaohui He, Jian Jiao, Tielong Liu, Bai Guangjian, Yujie Liu, Guanghui Chen, Wei Xu, Liu Weibo, Jianru Xiao, Zhengyu Gao, Xinghai Yang, Haifeng Wei
Publikováno v:
Gene. 665
Background Lung cancer leads to the largest number of cancer-related deaths worldwide and is usually accompanied with metastasis which is the primary cause of those death and correlated with poor prognosis. However, the mechanism of lung cancer metas
Autor:
Xinghai Yang, Jianru Xiao, Tielong Liu, Zhi’an Liu, Dianwen Song, Zhipeng Wu, Jing Wang, Wangjun Yan, Zhenxi Li, Wang Zhou, Huabin Yin, Ting Wang, Quan Huang, Haifeng Wei
Publikováno v:
Oncotarget
// Ting Wang 1,* , Huabin Yin 1,* , Jing Wang 1,2,* , Zhenxi Li 1 , Haifeng Wei 1 , Zhi’an Liu 2 , Zhipeng Wu 1 , Wangjun Yan 1 , Tielong Liu 1 , Dianwen Song 1 , Xinghai Yang 1 , Quan Huang 1 , Wang Zhou 1 and Jianru Xiao 1 1 Department of Bone Tu
Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR
Autor:
Xinghai Yang, Jinsong Li, Huayun Deng, Song Wu, Yuanzhang Fang, Leqin Xu, Shijie Chen, Zhenxi Li, Xiaopan Cai, Amanda Vaughn, Jianru Xiao, Meichun Hu, Wei Wan
Publikováno v:
Oncotarget
The epidermal growth factor receptor (EGFR) is a therapeutic target (oncotarget) in NSCLC. Using in vitro EGFR kinase activity system, we identified a novel small molecule, WB-308, as an inhibitor of EGFR. WB-308 decreased NSCLC cell proliferation an
Autor:
Tielong Liu, Huabin Yin, Ting Wang, Wei Xu, Wangjun Yan, Jia Chen, Zhenxi Li, Haiyan Chen, Wang Zhou, Jianru Xiao, Dianwen Song, Xinghai Yang, Zhipeng Wu
Publikováno v:
Bone. 66:267-276
Parathyroid hormone-related protein (PTHrP) has been identified to play a crucial role in osteolysis formation and stromal cell (GCTSC) proliferation in giant cell tumor (GCT). MiR-126-5p is an intronic miRNA identified as tumor suppressor in many tu