Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xianliang Zhang"'
Publikováno v:
Molecular neurobiology. 60(1)
Although treadmill exercise is effective against Alzheimer's disease (AD), the molecular mechanisms underlying these effects are not fully understood. Recent literature has linked the accumulation of damaged mitochondria and defective mitophagy to AD
Publikováno v:
Carbohydrate Polymers. 216:45-53
Herein the construction of a strong gelatin hydrogel is presented by using pullulan dialdehyde (PDA) as a macromolecular crosslinker. The resultant PDA crosslinked gelatin hydrogels (G-PDA) exhibit extremely high mechanical strength, manifested in th
Publikováno v:
Brain research bulletin. 165
Although previous studies showed that exercise can improve cognitive dysfunction in type 2 diabetes (T2DM), the underlying mechanism remains unclear. Sirtuin 1 (SIRT1) has been shown to play a role in regulating inflammatory responses in the brain an
Publikováno v:
Neuroreport. 31(5)
Recent study has demonstrated that high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) have the same effect to alleviate β-amyloid pathology in the hippocampus of APPswe/PS1dE9 (APP/PS1) mice. Activation of nucl
Publikováno v:
NeuroReport. 29:819-825
The β-amyloid (Aβ) deposition is one of the major pathological hallmark of Alzheimer's disease. Dysfunction in autophagy has been reported to lead to the Aβ deposition. The current study aimed to investigate the effects of treadmill exercise on au
Publikováno v:
Neurochemical research. 45(5)
Mitochondrial dysfunction is a hallmark of Alzheimer’s disease (AD), which may be related to mitophagy failure. Previous reports suggest that treadmill exercise protects against mitochondrial dysfunction in AD. However, few studies have investigate
Autor:
Yongcai Zhao, Yidong Bai, Baixia Li, Xianliang Zhang, Xiaoyan Ding, Tao Huang, Qing-Wei Yan, Bo Xu, Fei Liang
Publikováno v:
Behavioural brain research. 376
Exercise is a non-pharmacological strategy that may help to protect against cognitive decline and reduce the risk of Alzheimer's disease. However, the optimal exercise modes for cognitive benefits are controversial. Mitochondrial function has been re
Publikováno v:
Neuroreport. 30(7)
The deposition of amyloid-β (Aβ) is one of the major pathological hallmarks of Alzheimer's disease (AD), and a higher cholesterol level is involved in the deposition of Aβ. Previous evidence suggested that exercise exerts neuroprotective effects i
Publikováno v:
The EMBO journal. 36(17)
Neuronal cilia that are formed at the dendritic endings of sensory neurons are essential for sensory perception. However, it remains unclear how the centriole‐derived basal body is positioned to form a template for cilium formation. Using fluoresce
Autor:
Zhiwen Zhu, Wei Li, Yihong Yang, Lianwan Chen, Long Miao, Yan Zhang, Guangshuo Ou, Xianliang Zhang, Hao Zhu
Publikováno v:
Cell research. 27(3)