Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Wayne B. Anderson"'
Publikováno v:
Proceedings of the National Academy of Sciences. 110:15800-15805
The dorsal raphe nucleus (DR) controls forebrain serotonin neurotransmission to influence emotional states. GABA neurotransmission in the DR has been implicated in regulating sleep/wake states and influencing anxiety and aggression. To gain insight i
Publikováno v:
Neuroscience Letters. 383:155-159
Previous studies have observed increased tachykinin NK 1 receptor immunoreactivity (NK 1 -IR) in the prefrontal cortex in subjects with schizophrenia. Since the subjects were medicated the possibility of a treatment effect could not be excluded. Thus
Publikováno v:
Journal of Biological Chemistry. 280:16772-16783
Amphotropic murine leukemia virus (A-MuLV) utilizes the PiT2 sodium-dependent phosphate transporter as its cell surface receptor to infect mammalian cells. The process of A-MuLV infection requires cleavage of the R peptide from the envelope protein.
Autor:
Michael J. Gould, Christopher W. Vaughan, Wayne B. Anderson, Romeo D. Torres, Vanessa A. Mitchell
Publikováno v:
Neuropharmacology. 81
The analgesic efficacy of cannabinoids in chronic pain models is limited by side-effects. It has been proposed that this might be overcome by using agents which indirectly activate the endocannabinoid system. We examined the analgesic and side-effect
Publikováno v:
Biochemical and Biophysical Research Communications. 261:779-783
Glutathione transferase zeta (GSTZ) catalyzes the biotransformation of α-haloalkanoic acids. Treatment of rats or humans with dichloroacetic acid prolongs its elimination half-life, and preliminary studies in this laboratory show that fluorine-lacki
Publikováno v:
Archives of Biochemistry and Biophysics. 363:121-128
In fibroblasts, the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) stimulates phospholipase D (PLD)-mediated hydrolysis of both phosphatidylcholine (PtdCho) and phosphatidylethanolamine (PtdEtn) by PKC-alpha-mediated nonphosph
Publikováno v:
Archives of Biochemistry and Biophysics. 363:246-258
Since tumor promoter benzoyl peroxide (BPO) mimics phorbol esters in some aspects, its effects on protein kinase C (PKC) were previously studied. However, in those studies due to the presence of thiol agents in the PKC preparations, the sensitive rea
Autor:
Danièle Evain-Brion, Wayne B. Anderson, Isabelle Gorin, Denis Marciano, Pascale Gerbaud, Françoise Raynaud, Charis Liapi
Publikováno v:
Free Radical Biology and Medicine. 22:623-632
Previous studies have established that cyclic AMP-dependent protein kinase (PKA) activity, as well as 8-azido-[32P]-cAMP binding to the RI and RII regulatory subunits, are decreased in cells from psoriatic patients compared to cells from normal patie
Autor:
Alma F. Ferrier, Douglas R. Lowy, Giovanna Benvenuto, Deborah K. Morrison, Jeffrey E. DeClue, Wayne B. Anderson, Michael Lee
Publikováno v:
Journal of Biological Chemistry. 272:2136-2142
The Raf-1 serine/threonine protein kinase plays a central role in many of the mitogenic signaling pathways regulating cell growth and differentiation. The regulation of Raf-1 is complex, and involves protein-protein interactions as well as changes in
Publikováno v:
Biochemical and Biophysical Research Communications. 223:98-103
Subcellular redistribution (translocation) was initiated by treatment of NIH 3T3 cells overexpressing different epitope-tagged fragments of PKC epsilon with PMA, and was analyzed by immunocytochemistry. The PMA-induced translocation of holo PKC epsil